Abstract
It has been previously shown that non-specific acute inflammatory reactions are able to modify the activity of lymphocytes and macrophages. In the present work we investigated whether such a reaction could interfere with the development of antibody responses. For this purpose, (C57B1/6xDBA/2)F1 mice were immunized with sheep red blood cells (SRBC) as a thymus dependent antigen or with TNP-LPS as a thymus-independent one, from 1 h to 5 days after the intrapleural injection of calcium pyrophosphate (CaPP) microcrystals or a dextran solution (MW 40 000).
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© 1980 MTP Press Limited
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Florentin, I., Pelletier, M., Mathe, G., Giroud, J.P. (1980). Modification of antibody responses during non-specific acute inflammation (Abstract). In: Willoughby, D.A., Giroud, J.P. (eds) Inflammation: Mechanisms and Treatment. Inflammation: Mechanisms and Treatment, vol 4. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-9423-8_82
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DOI: https://doi.org/10.1007/978-94-010-9423-8_82
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-9425-2
Online ISBN: 978-94-010-9423-8
eBook Packages: Springer Book Archive