Abstract
The effects of cancer upon the host are varied and complex. In addition to direct tumor invasion, obstruction of vital organs and metastatic spread, tumors can elaborate soluble factors and humoral substances which influence the ability of the host to function normally. These remote effects constitute an assortment of ‘paraneoplastic syndromes’ which have perplexed scientists and clinicians for over a century. In this chapter we will review many of the commonly encountered syndromes, discuss their significance, and attempt to integrate them into the modern concept of oncogenesis with specific reference to the emerging understanding of the molecular genetics of cancer. We also refer the interested reader to the many excellent reviews on the topic which have been published in recent years (8, 70, 113, 116, 125, 153, 163, 171).
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Keywords
- Nephrotic Syndrome
- Paraneoplastic Syndrome
- Acanthosis Nigricans
- Hypertrophic Osteoarthropathy
- Ectopic ACTH Production
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Nagourney, R.A., Woolley, P.V. (1989). Paraneoplastic Syndromes. In: Liotta, L.A. (eds) Influence of Tumor Development on the Host. Cancer Growth and Progression, vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2528-1_16
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DOI: https://doi.org/10.1007/978-94-009-2528-1_16
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-7642-5
Online ISBN: 978-94-009-2528-1
eBook Packages: Springer Book Archive