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Electronic Circular Dichroism Spectroscopy in Structural Analysis of Biomolecular Systems

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Optical Spectroscopy and Computational Methods in Biology and Medicine

Part of the book series: Challenges and Advances in Computational Chemistry and Physics ((COCH,volume 14))

Abstract

In this chapter, the use of electronic circular dichroism (CD) in structural analysis of biological molecular systems is discussed. The quantum chemical theory of the phenomenon is briefly presented, and the applications of the CD spectroscopy in determination of spatial structure of proteins and nucleic acids, and of absolute configuration of small molecules of pharmacological significance are summarized. Some attention is also paid to the emerging technique related to CD—circularly polarized luminscence (CPL).

(Dated: 1 February 2013)

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Authors and Affiliations

  1. Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093, Warszawa, Poland

    Magdalena Pecul & Wojciech Dzwolak

Authors
  1. Magdalena Pecul
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  2. Wojciech Dzwolak
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Correspondence to Magdalena Pecul .

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Editors and Affiliations

  1. Faculty of Chemistry, Jagiellonian University, Ingardena 3, Krakow, Poland

    Malgorzata Baranska

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Pecul, M., Dzwolak, W. (2014). Electronic Circular Dichroism Spectroscopy in Structural Analysis of Biomolecular Systems. In: Baranska, M. (eds) Optical Spectroscopy and Computational Methods in Biology and Medicine. Challenges and Advances in Computational Chemistry and Physics, vol 14. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7832-0_6

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