Samenvatting
In dit hoofdstuk komt aan de orde op welke wijze het individu zelfregulatie bereikt, hoe ervaringen hierbij een rol spelen, hoe deze ervaringen neurobiologisch worden opgeslagen, en welke plaats het vermogen tot mentaliseren hierin inneemt. Emoties en hun regulatie blijken een cruciale rol te spelen bij het tot expressie brengen van de genetische opmaak door omgevingsinvloeden, de zogenoemde gen-omgevingsinteractie. Op grond van een model wordt verklaarbaar hoe omgevingsinvloeden via het tot expressie brengen van genen blijvende veranderingen teweeg kunnen brengen in het vermogen van het individu zichzelf te reguleren. Het beeld van persoonlijkheidsstoornissen is dus niet compleet zonder aandacht voor het ontstaan van de regulatie van emoties in het vroege leven. Deze moderne inzichten vanuit de neurowetenschappen zijn onzes inziens zeer bruikbaar bij het verkrijgen van een beter begrip van de pathogenese van persoonlijkheidsstoornissen en leiden in de toekomst wellicht tot andere indelingscategorieën en behandelstrategieën.
Literatuur
Bateman, A. W., & Fonagy, P. (1999). The effectiveness of partial hospitalization in the treatment of borderline personality disorder: A randomized controlled trial. American Journal of Psychiatry, 156, 1563–1569.
Bateman, A. W., & Fonagy, P. (2001). Treatment of borderline personality disorder with psychoanalytically oriented partial hospitalization: An 18-month follow-up. American Journal of Psychiatry, 158(1), 36–42.
Bateman, A. W., & Fonagy, P. (2004a). Mentalization-based treatment of BPD. Journal of Personality Disorders, 18(1), 36–51.
Bateman, A. W., & Fonagy, P. (2004b). Psychotherapy for borderline personality disorder: Mentalization-based treatment. Oxford: Oxford University Press.
Beebe, B. (2000). Co constructing mother-infant distress: The microsynchrony of maternal impingement and infant avoidance in the face-to-face encounter. Psychoanalytic Inquiry, 20(3), 421–440.
Beebe, B., & Lachmann, F. M. (1998). Co-constructing inner and relational processes: Self and mutual regulation in infant research and adult treatment. Psychoanalytic Psychology, 15, 1–37.
Beebe, B., & Lachmann, F. M. (2002). Infant research and adult treatment; co-constructing interactions. Hillsdale NJ/London: The Analytic Press.
Beebe, B., Lachmann, F. M., & Jaffe, J. (1997). Mother-infant interaction structures and presymbolic self and object representations. Psychoanalytic Dialoque, 7, 133–182.
Biringen, Z., Robinson, J. L., & Emde, R. N. (2000). Appendix B: The emotional availability scales (3rd ed., an abridged infancy/early childhood version). Attachment & Human Development, 2(2), 256–270.
Bliss, T. V. P., & Lomo, T. (1973). Long lasting potentiation of synaptic transmission in the dentate gyrus of the anesthetized rabbit following stimulation of the perforant path. Journal of Physiology (Lond), 232, 331–356.
Bozarth, M. A., & Wise, R. A. (1981). Intracranial self-administrition of morphine into the ventral tegmental area of rats. Life Sciences, 28, 551–555.
Brown, J. R., & Dunn, J. (1996). Continuities in emotion understanding from three to six years. Child Development, 67, 789–802.
Brown, M. R., Fisher, L. A., Spiess, J., Rivier, C., Rivier, J., & Vale, W. (1982). Corticotrophin-releasing factor: Actions on the sympathetic nervous system and metabolism. Endocrinology, 111, 928–931.
Caspi, A., McClay, J., Moffitt, T. E., Mill, J., Martin, J., Craig, I. W. T. A., et al. (2002). Role of genotype in the cycle of violence in maltreated children. Science, 297, 851–854.
Caspi, A., Sugden, K., Moffitt, T. E., Taylor, A., Craig, I. W., Harrington, H., et al. (2003). Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene. Science, 301, 386–389.
Cole, P. M., Michel, M. K., & Teti, L. O. (1994). The development of emotion regulation and dysregulation: A clinical perspective. Monographs of the Society for Research in Child Development, 240(59), 73–102.
Coplan, J. D., Altemus, M., Mathew, S. J., Smith, E. L., Sharf, B., Coplan, P. M., et al. (2005). Synchronized maternal-infant elevations of primate CSF CRF concentrations in response to variable foraging demand. CNS Spectrums, 10(7), 530–536.
Crockenberg, S. (1981). Infant irritability, mother responsiveness, and social support influences on the security of mother-infant attachment. Child Development, 52, 857–865.
DeGanghi, G. (2000). Pediatric disorders of regulation in affect and behavior. San Diego, London, Boston, New York, Sydney, Tokyo, Toronto: Academic Press.
Demos, V. (1991). Resilience in infancy. In T. F. Dugan & R. Coles (Red.), The child in our times: Studies in the development of resiliency. New York: Brunner/Mazel.
Emde, R. N. (1983). Pre-representational self and its affective core. Psychoanalytic Study of the Child, 38, 165–192.
Emde, R. N. (1999). Moving ahead: Integrating influences of affective processes for development and for psychoanalysis. International Journal of Psychoanalysis, 80, 317–340.
Field, T. (1985). Attachment as psychobiological attunement: Being on the same wavelength. In M. Reite & T. Field (Red.), The Psychobiology of Attachment and Separation. Orlando: Academic Press.
Fogel, A. (1982). Affect dynamics in early infancy. In T. Field & A. Fogel (Red.), Emotion and early interaction. Hillsdale, NJ: Erlbaum.
Foley, D. L., Eaves, L. J., Wormley, B., Silberg, J. L., Maes, H. H., Kuhn, J., et al. (2004). Childhood adversity, monoamine oxidase a genotype, and risk for conduct disorder. Archives of General Psychiatry, 61, 738–744.
Fonagy, P., Gergely, G., Jurist, E. L., & Target, M. (2002). Affect regulation, mentalization, and the development of the self. New York: Other Press.
Fonagy, P., & Target, M. (1996). Playing with reality: I. Theory of mind and the normal development of psychic reality. The International Journal of Psycho-Analysis, 77, 217–234.
Fonagy, P., & Target, M. (2000). Playing with reality: III. The persistence of dual psychic reality in borderline patients. The International Journal of Psycho-Analysis, 81, 853–874.
Fraga, M. F., Ballestar, E., Paz, M. F., Ropero, S., Setien, F., Ballestar, M. L., et al. (2005). Epigenetic differences arise during the lifetime of monozygotic twins. Proceedings National Academy of Sciences USA, 102(30), 10604–10609.
Francis, D., Diorio, J., Liu, D., & Meaney, M. J. (1999). Nongenomic transmission across generations of maternal behavior and stress responses in the rat. Science, 286(5), 1155–1159.
Gabbard, G. O. (2005). Mind, brain, and personality disorders. American Journal of Psychiatry, 162(4), 648–655.
Gael, M. van. (2002). De missing link tussen trauma en borderline problematiek. Een benadering vanuit de hechtingstheorie. Tijdschrift voor Psychotherapie, 28(5), 365–384.
Gallese, V. (2003a). The manifold nature of interpersonal relations: The quest for a common mechanism. Philosophical Transactions of the Royal Society of London. Series B, 358, 517–528.
Gallese, V. (2003b). The roots of empathy: The shared manifold hypothesis and the neural basis of intersubjectivity. Psychopathology, 36, 171–180.
Gallese, V. (2006). Mirror neurons and intentional attunement: commentary on olds. Journal of the American Psychoanalytic Association, 54(1), 47–57.
Gormally, S. M., & Barr, R. G. (1997). Of clinical pies and clinical cues: Proposal for a clinical approach to complaints of early crying and colic. Good Practice Guide, 3, 137–153.
Gottlieb, G. (1997). Synthesizing nature and nurture. Mahwah, New Jersey: Lawrence Erlbaum Associates, Publishers.
Grosjean, B. (2005). From synaps to psychotherapy. American Journal of Psychotherapy, 59(3), 181.
Haldane, J. B. S. (1946). The interaction of nature and nurture. Annuals of Eugenetics, 13, 197–205.
Hamer, D. (2002). Rethinking behavior genetics. Science, 298, 71–72.
Hebb, D. O. (1949). Organization of behavior: A neuropsychological theory. New York: Wiley.
Heim, C., Plotsky, P. M., & Nemeroff, C. B. (2004). Importance of studying the contributions of early adverse experience to neurobiological findings in depression. Neuropsychopharmacology, 29(4), 641–648.
Iacoboni, M., Molnar-Szakacs, I., Gallese, V., Buccino, G., Mazziotta, J. C., & Rizzolatti, G. (2005). Grasping the intentions of others with one’s own mirror neuron system. Plos Biology, 3(3), 529–535.
Iacoboni, M., Woods, R., Brass, M., Bekkering, H., Mazziotta, J. C., & Rizzolatti, G. (1999). Cortical mechanisms of human imitation. Science, 286, 2526–2528.
Iacoboni, M., Woods, R. P., Brass, M., Bekkering, H., Mazziotta, J. C., & Rizzolatti, G. (2000). Mirror properties in a sulcus angularis area. NeuroImage, 5(2), 821.
Kandel, E. R. (2001a). (Keynote Lecture American Psychiatric Association 2001 Annual Meeting, New Orleans) ‘Genes, Synapses, and Long-term Memory’.
Kandel, E. R. (2001b). The molecular biology of memory storage: a dialogue between genes and synapses. Science, 294, 1030–1038.
Kaufman, J., Yang, B. Z., Douglas-Palumberi, H., Houshyar, S., & Lipschitz, D. (2004). Social support and serotonin transporter gene moderate depression in maltreated children. Proceedings of the National Academy of Sciences, 101(49), 17316–17321.
Kloet, E. R. de, Joels, M., & Holsboer, F. (2005). Stress and the brain: From adaptation to disease. Nature Reviews of Neuroscience, 6(6), 463–475.
Kloet, E. R. de, Grootendorst, J., Karssen, A. M., & Oitzl, M. S. (2002). Gene × Environment interaction and cognitive performance: Animal studies on the role of corticosterone. Neurobiology of Learning and Memory, 78, 570–577.
Kohler, E., Keysers, C., Umilta, M. A., Fogassi, L., Gallese, V., & Rizzolatti, G. (2002). Hearing sounds, understanding actions: Action representation in mirror neurons. Science, 297(5582), 846–848.
Laible, D. J., & Thompson, R. A. (1998). Attachment and emotional understanding in preschool children. Development Psychology, 34(5), 1038–1045.
McEwen, B. S. (2003). Early life influences on life-long patterns of behavior and health. Mental Retardation and Development Disability Research Review, 9(3), 149–154.
Meaney, M. J. (2001). Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations, 24, 1161–1192.
Meaney, M. J. (2004). The nature of nurture: maternal affects and chromatine remodeling. In J. T. Cacioppo & G. G. Berntson, (Red.) Essays in social neuroscience. Cambridge Massachusetts; London England: The MIT Press.
Meaney, M. J., & Szyf, M. (2005). Maternal care as a model for experience-dependent chromatic plasticity? Trends in Neurosciences, 28, 456–463.
Moffitt, T. E. (2005). Genetic and environmental influences on antisocial behaviors: evidence from behavioral-genetic research. Advances in Genetics, 55, 41–104.
Moffitt, T. E., Caspi, A., & Rutter, M. (2005). Strategy for investigating interactions between measured genes and measured environments. Archives of General Psychiatry, 62, 473–481.
National Research Counsel. Institute of Medicine. (2000). From neurons to neighbourhoods; The science of early childhood development. Washington DC: National Academic Press.
Newport, D. J., Stowe Zachary, N., & Nemeroff, C. B. (2002). Parental depression: Animal models of an adverse life event. American Journal of Psychiatry, 159(8), 1265–1283.
Ormel, J. (2005). Personal communication (Symposium Gene-Environment Interaction). Groningen.
Papousec, M., & Hofacker, N. von. (1998). Persistent crying in early infancy: a non-trivial condition of risk for the developing mother-infant relationship. Child Care, Health, and Development, 24(5), 395–424.
Perry, B. D., Pollard, R. A., Blakley, T. L., et al. (1995). Childhood trauma, the neurobiology of adaptation, and ‘use-dependent’ development of the brain: How ‘states’ become ‘traits’. Infant Mental Health Journal, 16(4), 271–291.
Plomin, R., & Rutter, M. (1998). Child development, molecular genetics and what to do with genes once they are found. Child Development, 69(4), 1223–1242.
Posner, M. I., & Rothbart, M. K. (2000). Developing mechanisms of self-regulation. Development and Psychopathology, 12, 427–441.
Ramachandran, V. S. (2000). Mirror neurons and imitation learning as the driving force behind ‘the great leap foward’ in human evolution. http://www.edge.org/3rd_culture/ramachandran/ramachandran_p2.html.
Rizzolatti, G., & Craighero, L. (2004). The mirror-neuron system. Annual Review of Neuroscience, 27, 169–192.
Rizzolatti, G., Fadiga, L., Gallese, V., & Fogassi, L. (1996a). Premotor cortex and the recognition of moter actions. Cognitive Brain Research, 3, 131–141.
Rizzolatti, G., Fadiga, L., Matelli, M., Bettinardi, V., Paulesu, E., Perani, D., et al. (1996b). Location of grasp representations in humans by PET: 1. Observation versus execution. Experimental Brain Research, 111, 246–252.
Sanchez, M. M., Ladd, C. O., & Plotsky, P. M. (2001). Early adverse experience as a developmental risk factor for later psychopathology: Evidence from rodent and primate models. Developmental Psychopathology, 13(3), 419–449.
Sapolsky, R. M. (2003). Stress and plasticity in the limbic system. Neurochemical Research, 28(11), 1735–1742.
Sapolsky, R. M. (2004). Mothering style and methylation. Nature Neuroscience, 7(8), 791–792.
Schore, A. N. (1994). Affect regulation and the origin of the self: The neurobiology of emotional development. Hillsdale, NJ: Lawrence Erlbaum.
Schore, A. N. (1996). The experience dependent maturation of a regulatory system in the orbital prefrontal cortex and the origin of developmental psychopathology. Development and Psychopathology, 8, 59–87.
Schore, A. N. (2001). Effects of a secure attachment relationship on right brain development, affect regulation, and infant mental health. Infant Mental Health Journal, 22(1–2), 7–67.
Schore, A. N. (2002). Clinical implications of a psychoneurobiological model of projective identification. In S. Alhanati (Ed.), Primitive mental states. Volume II: Psychobiological and psychoanalytical perspectives on early trauma and personality development. London: Karnac.
Schore, A. N. (2003). Affect dysregulation and disorders of the self. New York/London: Norton.
Stern, D. N. (1985). The interpersonal world of the infant: A view from psychoanalysis and developmental psychology. New York: Basic Books.
Target, M., & Fonagy, P. (1996). Playing with reality: II. The development of psychic reality from a theoretical perspective. The International Journal of Psycho-Analysis, 77, 459–479.
Trojan, S., & Pokorny, J. (1999). Theoretical aspects of neuroplasticity. Physiological Research, 48, 87–97.
Visser, J. C. (2005). DC 0–3 diagnostische classificatie van psychische en ontwikkelingsstoornissen bij infants. Assen: Koninklijke Van Gorcum.
Weaver, I. C., Cervoni, N., Champagne, F. A., D’Alessio, A. C., Sharma, S., Seckl, I. R., et al. (2004). Epigenetic programming by maternal behavior. Nature Neuroscience, 7(8), 847–854.
Zahn-Waxler, C., & Kochanska, G. (1990). The origins of guilt. In R. A. Thomson (red.), Socioemotional development. Lincoln, NE: University of Nebraska Press.
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Schmeets, M., van Reekum, A. (2017). Infantonderzoek en neurowetenschappen. In: Eurelings-Bontekoe, E., Verheul, R., Snellen, W. (eds) Handboek persoonlijkheidspathologie. Bohn Stafleu van Loghum, Houten. https://doi.org/10.1007/978-90-368-0931-3_2
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