Summary
This presentation dealt with the contributions of German virologists in the rapid development of virology following the Loeffler-Frosch era. Thereby, only research was included which was undertaken within German institutions, even though guest scientists from other countries or international cooperative efforts have in some cases contributed to the work. Contributions to the field of veterinary virology were not considered here, since this topic was treated separately during this centennial symposium.
The overview includes contributions of the very early period when interest was focussed mainly on the determination of the physicochemical properties of the fast growing number of newly detected viruses, and of the pioneering period when fundamental discoveries of the nature of viruses were made. The concepts that derived from those studies made the development of modern virology possible. Some highlights of the present period were presented describing the findings of selected virus families. This part was followed by a description of the results which were relevant to problems of how viruses become pathogens, and the role of the immune response to virus infections. Finally, attention was drawn to the contributions of molecular studies which became important not only for the field of virology but also for life sciences in general.
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Keywords
- Influenza Virus
- Tobacco Mosaic Virus
- Epidermodysplasia Verruciformis
- Laryngeal Papilloma
- Herpesvirus Saimiri
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
References
Löwenstein A (1919) Mün Med Wochenschr 66: 769
Schneweis KE (1962) Z Immunforsch 124: 24
Siegelt R, Shu H-L, Slenczka W, Peters D, Müller G (1967) Dtsch Med Wochenschr 51: 2341
zur Hausen, Gissmann L (1979) Med Microbiol Immunol 167: 137
Zwick W, Seifried O, Witte J (1926) Z Inf Krankh Haustiere 30: 42
Rott, R, Herzog S, Bechter K, Frese K (1991) Arch Virol 118: 295
zur Hausen H, de Villiers EM (1994) Ann Rev Microbiol 48: 427
Mrowka (1912) Zbl Bakt Parasitkd 67: 249
Schlesinger M (1933) Biochem Z 273: 306
Kausche GA, Pfankuch E, Ruska H (1939) Naturwissenschoften 27: 292
Ruska H (1941) Arch Virusforsch 2: 345
Kleinschmidt AK, Lang D, Jacherts D, Zahn RK (1962) Biochim Biophys Acta 61: 131
Schlesinger M (1932) Z Hyg Infektkrankh 114: 149
Weidel W (1958) Ann Rev Microbiol 12: 27
Koch G, Dreyer WJ (1958) Virology 6: 291
Stanley WM (1935) Science 81: 644
Thomssen R (1963) Nature 198: 613
Eggers HJ (1982) In: Handbook of Experimental Pharmacology 61: 377
Schneweis KE, Brado M, Ebers B, Friedrich A, Olbrich M, Schüler W (1988) Med Microbiol Immunol 177: 1
Kandolf R(1993) Intervirology 35: 140
Bergold G (1947) Z Naturforsch 2b: 122
Bergold G (1948) Z Naturforsch 3b: 338
Schramm G (1943) Naturwissenschaften 31: 94
Anderer FA, Uhlig H, Weber E, Schramm G (1960) Nature 186: 922
Wittmann HG (1962) Z Vererbungslehre 93: 491
Gierer A, Schramm G (1956) Z Naturforsch 1 1b: 138
Wecker E (1959) Virology 7: 241
Schuster H (1960) Biochem Biophys Res Commun 2: 320
Schuster H (1961) J Mol Biol 3: 447
Gierer A, Mundry KW (1958) Nature 182: 1457
Anderer FA (1963) Biochim Biophys Acta 71: 246
Schäfer W (1963) Bacteriol Rev 27: 1
Schäfer W (1955) Z Naturforsch 10b: 81
Klenk E, Faillard H, Lempfried H (1995) Z Physiol Chem 301: 235
Schäfer W, Zillig W (1954) Z Naturforsch 9b: 779
Breitenfeld PM, Schäfer W (1957) Virology 4: 328
Wecker E (1957) Z Naturforsch 12b: 208
Scholtissek C, Rott R (1963) Nature 199: 200
Mueller GC, v Zahn-Ullmann S, Schäfer W (1960) J Biol Chem 235: 660
Rott R (1997) Berl Münch Tierärztl Wochenschr 110: 241
Klenk H-D, Garten W (1994) Trends Microbiol 2: 39
Schwarz RT, Datema R (1980) Trends Biochem Sci 5: 65
Veit M, Schmidt MFG (1998) Methods Mol Biol 88: 227
Klenk HD, Rott R, Orlich M, Blödorn J (1975) Virology 68: 426
Herrler G, Rott R, Klenk H-D, Müller H-P, Schukla AK, Schauer R (1985) EMBO J 4: 1503
Graffi A, Bielka H, Frey F, Scharsch F, Weiss R (1955) Wien Klin Wochenschr 105: 61
Schäfer W, Bolognesi DP, de Noronha F, Fischinger PJ, Hunsmann G, Ihle JN, Moennig V, Schwarz H, Thiel H-J (1977) Med Microbiol Immunol 164: 217
Möiling K, Bolognesi DP, Bauer H, Busen W, Plassmann HW, Hausen P (1971) Nature New Biol 234: 240
Sänger HL (1969) J Virol 3: 304
Sänger HL (1972) Adv Biosci 8: 103
Sänger HL, Klotz G, Riesner D, Gross HJ, Kleinschmidt AK (1976) Proc Natl Acad Sci USA 73: 3852
Domdey H, Jank P, Sänger HL, Gross HJ (1978) Nucleic Acids Res 5: 1221
Burell CJ, Mackay P, Greenaway PJ, Hofschneider HP, Murray K (1979) Nature 279: 43
Pasak M, Goto T, Gilbert W, Zink B, Schaller H et al. (1979) Nature 282: 575
Will H, Cattaneo R, Koch HG, Darai G, Schaller H et al. (1982) Nature 299: 740
Cattaneo R, Will H, Schaller H (1984) EMBO J 3: 2191
Heermann KH, Goldmann U, Schwartz W et al. (1984) J Virol 52: 396
Uy A, Bruss V, Gerlich WH, Köchel HG, Thomssen R (1986) Virology 155: 89
Zahn P, Hofschneider PH, Koshy R (1988) Oncogene 3: 169
Höhne M, Schaefer S, Seifer M et al. (1990) EMBO J 9: 1 137
Schlüter V, Meyer M, Hof-Schneider PH et al. (1994) Oncogene 9: 3 335
Gissmann L, zur Hausen H (1976) Proc Natl Acad Sci USA 73: 1 310
Gissman L, Pfister H, zur Hausen H (1976) Virology 76: 569
Durst M, Gissmann L, Kenberg H, zur Hausen H (1983) Proc Natl Acad Sci USA 80: 3812
Pfister H (1992) Semin Cancer Biol 3: 263
zur Hausen H (1994) Curr Topics Microbiol Immunol 186: 131
Pfister H (1996) Obstet Gynecol Clinics 23: 579
Graf T, Beug H (1983) Cell 34: 7
Donner P, Greiser-Wilke I, Moelling K (1982) Nature 296: 262
Donner P, Bunte T, Greiser-Wilke I, Moelling K (1983) Proc Natl Acad Sci USA 80: 2 861
Moelling K, Heimann, B, Beimling P, Rapp UR, Sander T (1984) Nature 312: 558
Grassmann R, Dengler C, Müller-Fleckenstein I et al. (1989) Proc Natl Acad Sci USA 86: 3 351
Jung JU, Trimble JJ, King NW et al. (1991) Proc Natl Acad Sci USA 88: 7 051
Biesinger B, Tsygankov A, Fickenscher H et al. (1995) J Biol Chem 270: 4 729
Wiesmüller C, Cammenga J, Deppert W (1986) J Virol 70: 737
Mummenbrauer T, Janus F, Müller B et al. (1996) Cell 85: 1089
Rott R, Orlich M, Scholtissek C (1979) J Gen Virol 44: 471
Rott R, Klenk H-D, Nagay Y, Tashiro M (1995) Am J Resp Crit Care Med 152: 516
Volchkov VE, Feldmann H, Volchkova VA, Klenk H-D (1998) Proc Natl Acad Sci USA 95: 5762
Lieben VG, Baczko K, Budka H, ter Meulen V (1986) J Gen Virol 67: 2435
Cattaneo R, Schmidt A, Spielhofer P et al. (1989) Virology 173: 415
Schlesinger RW, Bradshaw GL, Barbone F et al (1989) J Virol 63: 1 695
Watanabe R, Wege H, ter Meulen V (1983) Nature 305: 150
Liebert VG, Lington, CC, ter Meulen V (1988) J Neuroimmunol 29: 139
Rott O, Herzog S, Cash E (1994) Med Microbiol Immunol 183: 195
Drzeniek R, Rott R (1969) Arch Allergy 36: 146
Kochs G, Trost M, Janzen G, Haller O (1998) Methods: A companion of Methods in Enzymology 15: 255
Koszinowski U, Thomssen R (1975) Eur J Immunol 5: 246
Koszinowski UH, Gething AH, Waterfield MD, Klenk HD (1980) J Exp Med 151: 945
Kurrle R, Wagner H, Röllinghoff M, Rott R (1979) Eur J Immunol 9: 107
Lehmann-Grube F (1984) Intervirology 22: 121
Lehmann-Grube F, Moskophidis D, Löhler J (1988) Ann NY Acad Sci 532: 238
Narayan O, Herzog S, Frese K, Rott R (1983) Science 220: 1401
Vallbracht A, Maier K, Stierhof YD et al. (1989) J Infect Dis 160: 209
Pirquet Cv (1908) Dtsch Med Wochenschr 30: 1297
Schlender J, Schnorr J-J, Spielhofer P et al. (1996) Proc Natl Acad Sci USA 93: 13194
Hengel H, Brune W, Koszinowski U (1998) Trends Microbiol 6: 190
Jaenisch R, Fan H, Croker B (1975) Proc Natl Acad Sci USA 72: 4 008
Jaenisch R (1982) Hoppe-Seyer’s Z Physiol Chem 363: 1 267
Hofschneider PH (1960) Z Naturforsch 15b: 441
Amann J, Delius H, Hof-Schneider PH (1964) J Mol Biol 10: 557
Pfeifer D (1961) Z Vererbungslehre 92: 312
Khatchikian D, Orlich, M, Rott R (1989) Nature 340: 156
Eigen M, McCaskill J, Schuster P (1983) J Physiol Chem 92: 6 881
Sumper M, Luce R (1975) Proc Natl Acad Sci USA 72: 162
Schaller H, Gray C, Herrmann K (1977) Proc Natl Acad Sci USA 74: 737
Messing J, Gronenborn B, Müller-Hill B, Hofschneider PH (1977) Proc Natl Acad Sci USA 74: 3 642
Kuroda K, Hauser C, Rott R, Klenk H-D, Doerfler W (1986) EMBO J 5: 1 359
Boshart M, Weber F, Jahn G et al. (1985) Cell 41: 521
Grosschedl R, Hobom G (1979) Nature 277: 621
Lehrrach H, Frischauf A (1983) J Mol Biol 170: 827
Schnell MJ, Mebastion T, Conzelmann K-K (1994) EMBO J 13: 4 195
Neumann G, Zobel A, Hobom G (1994) Virology 202: 477
Messerle M, Crnkovic I, Hammerschmidt W et al. (1997) Proc Natl Acad Sci USA 94: 14 759
Decluse H, Hilsenberger T, Pich D et al (1998) Proc Natl Acad Sci USA 95: 8 245
Sutter D, Westphal M, Doerfler W (1978) Ann Rev Biochem 52: 93
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Rott, R. (1999). The post-Loeffler-Frosch era: contribution of German virologists. In: Calisher, C.H., Horzinek, M.C. (eds) 100 Years of Virology. Archives of Virology. Supplementa, vol 15. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6425-9_4
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DOI: https://doi.org/10.1007/978-3-7091-6425-9_4
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