Skip to main content
SpringerLink
Log in

Vulvakarzinom

  • Chapter
  • First Online:
Book cover Therapiehandbuch Gynäkologie und Geburtshilfe

  • 4789 Accesses

Zusammenfassung

Das Vulvakarzinom ist als vierthäufigstes weibliches Genitalmalignom eher selten. Daher sind Studien zu den verschiedenen Fragestellungen meist rein retrospektiv an relativ kleinen Fallzahlen durchgeführt worden und damit die Evidenzlevel der therapeutischen Empfehlungen gering. Andererseits sind die therapeutischen Algorithmen im besonderen Maße für seltene Fragestellungen nur gering vertraut.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 119.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Literatur

  • Abang Mohammed DK, Uberoi R, de B Lopes A, Monaghan JM (2000) Inguinal node status by ultrasound in vulva cancer. Gynecol Oncol 77:93–96

    Google Scholar 

  • Ansink A, van der Velden J (1999) Surgical interventions for early squamous cell carcinoma of the vulva. Cochrane Database Syst Rev (1999)4:CD002036

    Google Scholar 

  • Ansink A, van der Velden J, Collingwood M (2005) Surgical interventions for eatly squamous cell carcinoma of the vulva (review). The Cochrane Collaboration, John Wiley & Sons, New York

    Google Scholar 

  • Chan JK, Sugiyama V, Pham H, Gu M, Rutgers J, Osann K, Cheung MK, Berman ML, Disaia PJ (2007) Margin distance and other clinico-pathologic prognostic factors in vulvar carcinoma: a multivariate analysis. Gynecol Oncol 104:636–641

    Article  Google Scholar 

  • Faul CM, Mirmow D, Huang Q, Gerszten K, Day R, Jones MW (1997) Adjuvant radiation for vulvar carcinoma: improved local control. Int J Radiat Oncol Biol Phys 38(2):381–389

    Article  CAS  Google Scholar 

  • FIGO Committee on Gynecologic Oncology (2009) Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium. Int J Gyn Obstet 105:103–104

    Article  Google Scholar 

  • Fox H, Wells M (2003) Recent advances in the pathology of the vulva. Histopathology 42:209–216

    Article  CAS  Google Scholar 

  • Groenen SM, Timmers PJ, Burger CW (2010) Recurrence rate in vulvar carcinoma in relation to pathological margin distance. Int J Gynecol Cancer 20:869–783

    Article  Google Scholar 

  • Hart WR (2001) Vulvar intraepithelial neoplasia: historical aspects and current status. Int J Gynecol Pathol 20:16–30

    Article  CAS  Google Scholar 

  • Heaps JM, FU YS, Montz FJ, Hacker NF, Berek JS (1990) Surgical-pathologic variables predictive of local recurrence in squamous cell carcinoma of the vulva. Gynecol Oncol 38:309–314

    Article  CAS  Google Scholar 

  • Höckel M, Schmidt K, Bornmann K, Horn LC, Dornhöfer (2010) Vulvar field resection: novel approach to the surgical treatment of vulvar cancer based on ontogenetic anatomy. Gynecol Oncol 119(1):106–113

    Article  Google Scholar 

  • Höckel M, Horn LC, Illig R, Dornhöfer N, Fritsch H (2011) Ontogenetic anatomy of the distal vagina: relevance for local tumor spread and implications for cancer surgery. Gynecol Oncol 122(2):313–318

    Article  Google Scholar 

  • Homesley HD, Bundy BN, Sedlis A, Adcock L (1986) Radiation therapy versus pelvic node resection for carcinoma of the vulva with positive groin nodes. Obstet Gynecol 68(6):733–740

    CAS  PubMed  Google Scholar 

  • Iacoponi S, Zapardiel I, Diestro MD, Hernandez A, De Santiago J (2013) Prognostic factors associated with local recurrence in squamous cell carcinoma of the vulva. J Gynecol Oncol 24:242–248

    Article  Google Scholar 

  • Interdisziplinäre S2k-Leitlinie für die Diagnostik und Therapie des Vulvakarzinoms und seiner Vorstufen; Kommission Vulva Vagina der Arbeitsgemeinschaft Gynäkologische Onkologie e. V. (2015) Zuckschwerdt, München

    Google Scholar 

  • Jones RW, Rowan DM, Stewart AW (2005) Vulvar intraepithelial neoplasia: aspects of the natural history and outcome in 405 women. Obstet Gynecol 106:1319–1326

    Article  Google Scholar 

  • Joura EA, Losch A, Haider-Angeler MG, Breitenecker G, Leodolter S (2000) Trends in vulvar neoplasia. Increasing incidence of vulvar intraepithelial neoplasia and squamous cell carcinoma of the vulva in young women. J Reprod Med 45:613–615

    CAS  PubMed  Google Scholar 

  • Katalinic A, Gerdemann U (2011) Aktuelle Zahlen zum Vulvakarzinom, Institut für Krebsepidemiologie e. V. an der Universität Lübeck, März 2011. http://www.krebsregister-sh.de/datenbank/Vulva2011.pdf

  • Kaushik S, Pepas L, Nordin A, Bryant A, Dickinson HO (2011) Surgical interventions for high grade vulval intraepithelial neoplasia. Cochrane Database Syst Rev 2011(1):CD007928

    Google Scholar 

  • Klemm P, Marnitz S, Koehler C, Braig U, Schneider A (2005) Clinical implication of laparoscopic pelvic lymphadenectomy in patients with vulvar cancer and positive groin nodes. Gynecol Oncol 99:101–105

    Article  Google Scholar 

  • Kunos C, Simpkins F, Gibbons H, Tian C, Homesley H (2009) Radiation therapy compared with pelvic node resection for node-positive vulvar cancer: a randomized controlled trial. Obstet Gynecol 114(3):537–546

    Article  Google Scholar 

  • Leiserowitz GS, Russell AH, Kinney WK, Smith LH, Taylor MH, Scudder SA (1997) Prophylactic chemoradiation of inguinofemoral lymph nodes in patients with locally extensive vulvar cancer. Gynecol Oncol 66(3):509–514

    Article  CAS  Google Scholar 

  • Maggino T, Landoni F, Sartori E et al (2000) Patterns of recurrence in patients with squamous cell carcinoma of the vulva. A Multicenter CTF Study. Cancer 89:116–122

    CAS  PubMed  Google Scholar 

  • Pepas L, Kaushik S, Bryant A, Nordin A, Dickinson HO (2011) Medical interventions for high grade vulval intraepithelial neoplasia, Cochrane Database Syst Rev (2011)4:CD007924

    Google Scholar 

  • Robert Koch-Institut (Hrsg) (2010) Krebs in Deutschland 2005/2006. Häufigkeiten und Trends. RKI, Berlin. http://edoc.rki.de/documents/rki_fv/re2vZ21t28Ir8Y/PDF/22aJOdYnmXV0I.pdf

  • Stehman FB, Bundy BN, Thomas G, Varia M, Okagaki T, Roberts J, Bell J, Heller PB (1992) Groin dissection versus groin radiation in carcinoma of the vulva: a gynecologic oncology group study. Int J Radiat Oncol Biol Phys 24(2):389–396

    Article  CAS  Google Scholar 

  • van der Velden J, Fons G, Lawrie TA (2011) Primary groin irradiation versus primary groin surgery for early vulvar cancer. Cochrane Database Syst Rev (2011)5:CD002224

    Google Scholar 

  • Van der Zee AGJ, Oonk MH, De Hullu JA, Ansink AC, Vergote I, Verheijen RH, Maggioni A, Gaarenstroom KN, Baldwin PJ, Van Dorst EB, Van der Velden J, Hermanns RH, Van der Putten H, Drouin P, Schneider A, Sluiter WJ (2008) Sentinel node dissection is safe in the treatment of early-stage vulvar cancer. J Clin Oncol 26:884–889

    Article  Google Scholar 

  • van Doorn HC, Ansink A, Verhaar-Langereis M, Stalpers L (2006) Neoadjuvant chemoradiation for advanced primary vulvar cancer. Cochrane Database Syst Rev (2006)3:CD003752

    Google Scholar 

  • van Seters M, van Beurden M, de Craen AJ (2005) Is the assumed natural history of vulvar intraepithelial neoplasia III based on enough evidence? A systematic review of 3322 published patients. Gynecol Oncol 97:645–651

    Article  Google Scholar 

  • Wittekind C, Meyer H-J (Hrsg) (2010) TNM-Klassifikation maligner Tumoren, 7. Aufl. Wiley-VCH, Weinheim

    Google Scholar 

  • Woelber L, Choschzick M, Eulenburg C, Hager M, Jaenicke F, Gieseking F, Kock L, Ihnen M, Petersen C, Schwarz J, Mahner S (2011) Prognostic Value of Pathological Resection Margin Distance in Squamous Cell Cancer of the Vulva. Ann Surg Oncol 18(13):3811–3818

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Klinik für Frauenheilkunde und Geburtshilfe, Kreiskliniken Altötting-Burghausen, Altötting, Deutschland

    Peer Hantschmann

Authors
  1. Peer Hantschmann
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Peer Hantschmann .

Editor information

Editors and Affiliations

  1. Fürst-Stirum-Klinik Bruchsal Frauenklinik, Bruchsal, Germany

    Jürgen Wacker

  2. Praxisklinik am Rosengarten, Mannheim, Germany

    Martin Sillem

  3. Praxisklinik am Rosengarten, Mannheim, Germany

    Gunther Bastert

  4. Frauenklinik, Universitätsklinikum Erlangen-Nürnberg Frauenklinik, Erlangen, Germany

    Matthias W. Beckmann

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Hantschmann, P. (2020). Vulvakarzinom. In: Wacker, J., Sillem, M., Bastert, G., Beckmann, M. (eds) Therapiehandbuch Gynäkologie und Geburtshilfe. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-59809-2_36

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-59809-2_36

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-59808-5

  • Online ISBN: 978-3-662-59809-2

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics

Search

Navigation