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Nanotechnology Characterization Tools for Tissue Engineering and Medical Therapy pp 241–297Cite as

Magneto-Responsive Nanomaterials for Medical Therapy in Preclinical and Clinical Settings

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Abstract

Magneto-responsive nanomaterials proved to be extremely beneficial in a whole bunch of industrial and commercial applications, ranging from catalytic systems, magnetic storage, photonic and electronic devices to biological and biomedical theranostics. In particular, the preparation of magnetic nanoparticles (MNPs), mainly made of iron oxides, for both diagnostics (detection, imaging, biosensing) and therapeutics (hyperthermia, magnetic targeting, and drug delivery) has occupied a privileged position among other nanocomposites. Due to their nanoscale dimensions, unique physiochemical properties, intrinsic magnetic characteristics, biocompatibilities, and abilities to function on the biomolecular and cellular levels, MNPs have been thoroughly investigated in medicine as magnetic imaging contrast-enhancing probes, hyperthermia agents, and magnetic-guided drug delivery carriers for disease theranostics. By avoiding healthy tissues, enabling reduced toxicities, and controlling the delivery of chemotherapeutics to specific locations, MNPs has indeed great potentials to increase drug therapeutic efficacies and minimize their adverse side effects giving promise for next-generation clinical nanomedicines for cancer treatment.

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Acknowledgment

The author would like to thank the continuous support by KSAU-HS, KAIMRC, and Ministry of National Guard Health Affairs. This work was funded by KAIMRC under grant RC13/204/R.

Financial and Competing Interests

The author declares no competing financial interests. No writing assistance was utilized in the production of this book chapter.

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Authors and Affiliations

  1. Department of Basic Sciences, College of Science & Health Professions (COSHP), King Saud bin Abdulaziz University for Health Sciences (KSAU-HS), King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, Saudi Arabia

    Kheireddine El-Boubbou

  2. King Abdullah International Medical Research Center (KAIMRC), King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, Saudi Arabia

    Kheireddine El-Boubbou

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  1. Kheireddine El-Boubbou
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Correspondence to Kheireddine El-Boubbou .

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  1. Integrated Mesoscale Architectures for Sustainable Catalysis (IMASC), Rowland Institute of Science, Harvard University, Cambridge, MA, USA

    Challa S.S.R. Kumar

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El-Boubbou, K. (2019). Magneto-Responsive Nanomaterials for Medical Therapy in Preclinical and Clinical Settings. In: Kumar, C. (eds) Nanotechnology Characterization Tools for Tissue Engineering and Medical Therapy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-59596-1_6

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