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Multiple Sequenzalignments: eine Einführung

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Zusammenfassung

Dieses Buch beschäftigt sich mit Programmen, die multiple Sequenzalignments (MSAs) erzeugen. Diese Programmklasse ist wahrscheinlich die am meisten genutzte und vielfältigste Programmklasse der Bioinformatik. In den letzten 30 Jahren wurden unzählige Programme und Ansätze entwickelt, um MSAs aus Protein- und DNA-Sequenzen zu erzeugen. Diese Programme belegen üblicherweise die ersten Kapitel der einschlägigen Bioinformatik-Lehrbücher und die ersten Stunden der meisten einführenden Vorlesungen. Dennoch verwenden Biologinnen und Biologen recht wenig Gehirnschmalz auf die Frage, welches der vielen verschiedenen Programme das optimale für das uns im Moment vorliegende Problem ist; wir benutzen einfach das eine Tool, das wir immer schon genutzt haben.

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Sperlea, T. (2019). Multiple Sequenzalignments: eine Einführung. In: Multiple Sequenzalignments. Springer Spektrum, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-58811-6_1

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