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Future Trends in Ligament Surgery: The Role of Biology

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Complex Knee Ligament Injuries

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Abstract

Ligament injury is a frequently cited cause of functional disability and affects people participating in a wide range of physical activities and levels of play. There are numerous potential benefits of ligament repair that include restoration of normal joint kinematics and preservation of proprioception, which may lead to improved long-term preservation of joint anatomy and function. The healing potential for certain ligament injuries is not ideal due to anatomic considerations of vascularity and availability of native reparative growth factors and cellular elements. There are several therapeutic options involving biologic treatments that are becoming more widely used. These therapies include bioactive growth factors and multipotent cellular therapies that can be used in isolation or in combination with surgical treatment to augment ligament repair and regeneration.

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Authors and Affiliations

  1. Orthopaedic Arthroscopic Surgery International (OASI) Bioresearch Foundation, Milan, Italy

    Graeme P. Whyte, Katarzyna Herman & Alberto Gobbi

  2. Weill Medical College, Cornell University, New York, NY, USA

    Graeme P. Whyte

  3. New York Presbyterian Hospital/Queens, New York, NY, USA

    Graeme P. Whyte

  4. Unit of Regenerative Therapy and Arthroscopic Surgery, Sanatorio Garay, Santa Fe, Argentina

    Ignacio Dallo

Authors
  1. Graeme P. Whyte
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  2. Ignacio Dallo
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  3. Katarzyna Herman
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  4. Alberto Gobbi
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Corresponding author

Correspondence to Alberto Gobbi .

Editor information

Editors and Affiliations

  1. Orthopaedics and Traumatology, University of Rome “Foro Italico”, Rome, Italy

    Fabrizio Margheritini

  2. Clínica do Dragão, Espregueira-Mendes Sports Centre - FIFA Medical Centre of Excellence, Porto, Portugal

    João Espregueira-Mendes

  3. O.A.S.I. Bioresearch Foundation NPO, Milan, Italy

    Alberto Gobbi

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Whyte, G.P., Dallo, I., Herman, K., Gobbi, A. (2019). Future Trends in Ligament Surgery: The Role of Biology. In: Margheritini, F., Espregueira-Mendes, J., Gobbi, A. (eds) Complex Knee Ligament Injuries. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-58245-9_18

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  • DOI: https://doi.org/10.1007/978-3-662-58245-9_18

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