Zusammenfassung
Obwohl die Depression bei älteren Erwachsenen ein weit verbreitetes Leiden ist, stellt sie keinen normalen Teil des Alterungsprozesses dar, sondern muss konsequent diagnostiziert und therapiert werden. Bemerkenswerterweise werden Depressionen bei älteren Patienten oft nicht erkannt, und wenn erkannt dann nicht behandelt. Depression ist im Alter häufig multifaktoriell und beeinflusst negativ Funktionen, Kognition und Lebensqualität. Die Verbesserung der Diagnose und die adäquate, auch nicht-medikamentöse Therapie sollte deshalb gezielt verfolgt werden. In diesem Kapitel werden diagnostische und therapeutische Optionen vorgestellt, die auch im fortgeschrittenen Alter die adäquate Behandlung der Depression erlauben.
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Bien B, Bien-Barkowska K (2016) Objective drivers of subjective well-being in geriatric inpatients: mobility function and level of education are general predictors of self-evaluated health, feeling of loneliness, and severity of depression symptoms. Qual Life Res 25:3047–3056
Bonin Guillaume S, Benoit B (2018) Depression. In: Roller-Wirnsberger R, Singler K, Polidori MC, eds. Learning geriatric medicine. Springer, Cham
Brunton L, Chapner B, Knollman B (2011) Goodman und Gillman’s the pharmacological basis of therapeutics. McGraw Hill, New York
Chang YC, Yao G, Hu SC, Wang JD (2015) Depression affects the scores of all facets of the WHOQOL-BREF and may mediate the effects of physical disability among community-dwelling older adults. PLoS One 10:e0128356
Cole MG, Bellavance F, Mansour A (1999) Prognosis of depression in elderly community and primary care populations: a systematic review and meta-analysis. Am J Psychiatry 156:1182–1189
Davin A, Monti MC, Polito L, Vaccaro R, Abbondanza S, Gnesi M, Villani S, Guaita A (2015) Influence of serotonin transporter gene polymorphisms and adverse life events on depressive symptoms in the elderly: a population-based study. PLoS One 10:e0143395
Davis JC, Bryan S, Li LC, Best JR, Hsu CL, Gomez C, Vertes KA, Liu-Ambrose T (2015) Mobility and cognition are associated with wellbeing and health related quality of life among older adults: a cross-sectional analysis of the vancouver falls prevention cohort. BMC Geriatr 15:75–81
de Araújo AA, Rebouças Barbosa RA, de Menezes MS, de Medeiros II, de Araújo RF Jr, de Medeiros CA (2016) Quality of life, family support, and comorbidities in institutionalized elders with and without symptoms of depression. Psychiatr Q 87:281–291
Falkai P, Wittchen H, Döpfner M et al (2015) Diagnostisches und Statistisches Manual Psychischer Störungen – DSM-5. Hogrefe, Göttingen
Fässberg MM, Cheung G, Canetto SS, Erlangsen A, Lapierre S, Lindner R, Draper B, Gallo JJ, Wong C, Wu J, Duberstein P, Woern M (2016) A systematic review of physical illness, functional disability ans suicidal behavior among older adults. Aging Ment Health 20:166–194
Gallagher D, Kiss A, Lanctot K, Herrmann N (2016) Depressive symptoms and cognitive decline: a longitudinal analysis of potentially modifiable risk factors in community dwelling older adults. J Affect Disord 190:235–240
Giebel CM, Sutcliffe C, Renom-Guteras A, Arve S, Hallberg IR, Soto M, Zabalegui A, Hamers J, Saks K, Challis D (2015) Depressive symptomatology in severe dementia in a European sample: prevalence, associated factors and prescription rate of antidepressants. Int Psychogeriatr 27:657–667
Ho C, Jin A, Nyunt MS, Feng L, Ng TP (2016) Mortality rates in major and subthreshold depression: 10-year follow-up of a Singaporean population cohort of older adults. Postgrad Med 128:642–647
Kok RM, Reynolds CF (2017) 3rd. Management of depression in older adults: a review. JAMA 317:2114–2122
Lund Jensen N, Pedersen HS, Vestergaard M, Mercer SW, Glumer C, Prior A (2017) The impact of socioeconomic status and multimorbidity on mortality: a population-based cohort study. Clin Epidemiol 9:279–289
Mulin E, Leone E, Dujardin K, Delliaux M, Leentjens A, Nobili F, Dessi B, Tible O, Agüera-Ortiz L, Osorio RS, Yessavage J, Dachevsky D, Verhey FR, Cruz Jentoft AJ, Blanc O, Llorca PM, Robert PH (2011) Diagnostic criteria for apathy in clinical practice. Int J Geriatr Psychiatry 26:158–165
Muralidharan A, Klingaman EA, Prior SJ, Molinari V, Goldberg RW (2016) Medical and psychosocial barriers to weight management in older veterans with and without serious mental illness. Psychol Serv 13:419–427
Nolen-Hoeksema S, Ahrens C (2002) Age differences and similarities in the correlates of depressive symptoms. Psychol Aging 17:116–124
Patel KV, Cochrane BB, Turk DC, Bastian LA, Haskell SG, Woods NF, Zaslavsky O, Wallace RB, Kerns RD (2016) Association of pain with physical function, depressive symptoms, fatigue, and sleep quality among veteran and non-veteran postmenopausal women. Gerontologist 56(1):S91–101
Pilotto A, Martin FC (Hrsg) (2018) Employer-Branding-Controlling. Springer, Berlin
Polidori C (2015) Alzheimer’s dementia and mood. In: Sun M-K (Hrsg) Cognition and mood interactions. Nova Science, UK S 105–116
Polidori MC, Menculini G, Senin U, Mecocci P (2001) Dementia, depression and parkinsonism: a frequent association in the elderly. J Alzheimers Dis 3:553–562
Pruchno RA, Wilson-Genderson M, Heid AR (2016) Multiple chronic condition combinations and depression in community-dwelling older adults. J Gerontol A Biol Sci Med Sci 71:910–915
Puvill T, Lindenberg J, de Craen AJ, Slaets JP, Westendorp RG (2016) Impact of physical and mental health on life satisfaction in old age: a population based observational study. BMC Geriatr 16:194
Radakovic R, Harley C, Abrahams S, Starr JM (2015) A systematic review of the validity and reliability of apathy scales in neurodegenerative conditions. Int Psychogeriatr 27:903–923
Reynolds CF III (2017) Evidence-based treatment and prevention of major depressive episodes in later life. In: Hazzard’s Geriatric Medicine and Gerontology. Ali McGraw Hil, New York State
Robert P, Onyke CU, Leentjens AF, Dujardin K, Aalten P, Starkstein S, Verhey FR, Yessavage J, Clement JP, Drapier D, Bayle F, Benoit M, Boyer P, Lorca PM, Thibaut F, Gauthier S, Grossberg G, Vellas B, Byrne J (2009) Proposed diagnostic criteria for apathy in Alzheimer’s disease and other neuropsychiatric disorders. Eur Psychiatry 24:98–104
Ruthirakuhan MT, Herrmann N, Abraham EH, Chan S, Lanctot KL (2018) Pharmacological interventions for apathy in Alzheimer’s disease. Cochrane Database Syst Rev 5:CD012197
Smagula SF, Ancoli-Israel S, Blackwell T, Boudreau R, Stefanick ML, Paudel ML, Stone KL, Cauley JA (2015) Circadian rest-activity rhythms predict future increases in depressive symptoms among community-dwelling older men. Am J Geriatr Psychiatry 23:495–505
Subramaniam M, Abdin E, Sambasivam R, Vaingankar JA, Picco L, Pang S, Seow E, Chua BY, Magadi H, Mahendran R, Shong SA (2016) Prevalence of depression among older adults-results from the well-being of the singapore elderly study. Ann Acad Med Singapore 45:123–133
Theleritis C, Siarkos K, Katirtzoglou E, Politis A (2017) Pharmacological and nonpharmacological treatment for apathy in Alzheimer disease: a systematic review across modalities. J Geriatr Psychiatry Neurol 30:26–49
Theleritis C, Siarkos K, Politis AA, Katirtzoglou E, Politis A (2018) A systematic review of non-pharmacological treatments for apathy in dementia. Int J Geriatr Psychiatry 33:e177–e192
Tisminetzky M, Bayliss EA, Magaziner JS, Allore HG, Anzuoni K, Boyd CM, Gill TM, Go AS, Greenspan SL, Hanson LR, Hornbrook MC, Kitzman DW, Larson EB, Naylor MD, Shirley BE, Tai-Seale M, Teri L, Tinetti ME, Whitson HE, Gurwitz JH (2017) Research priorities to advance the health and health care of older adults with multiple chronic conditions. J Am Geriatr Soc 65:1549–1553
Vialou V, Feng J, Robison AJ, Nestler EJ (2013) Epigenetic mechanisms of depression and antidepressant action. Annu Rev Pharmacol Toxicol 53:59–87
Wee N, Kandiah N, Acharyya S, Chander RJ, Ng A, Au WL, Tan LC (2016) Depression and anxiety are co-morbid but dissociable in mild Parkinson’s disease: a prospective longitudinal study of patterns and predictors. Parkinsonism Relat Disord 23:50–56
Wolter DK (2016a) Depression in old age, part 1: Origin, clinical symptoms, diagnosis and interaction between depression and dementia. Z Gerontol Geriatr 49:335–348
Wolter DK (2016b) Depression in old age, part 2: Comorbidity and treatment. Z Gerontol Geriatr 49:437–452
Zemke J (2018) Die drei großen D: Demenz – Delir – Depression. Geriatr Gerontol Pfl 2(2):78–81
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Polidori, M.C., Meyer, A.M. (2019). Depression. In: Maetzler, W., Dodel, R., Jacobs, A. (eds) Neurogeriatrie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-57358-7_8
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