Abstract
In a delightful essay Lwoff (1957), scrutinizing the various types of infection, concludes “that the essence of infection is not the disease, but the introduction into an organism of a foreign entity able to multiply, to produce a disease and to reproduce infectious entities.” In the case of infection by viruses the foreign entity entering the host cell is essentially the genetic material of the virus, i.e. nucleic acid, either naked or very nearly so as with bacteriophages, or bound to protein as with tobacco mosaic virus and polio virus, or associated with protein and surrounded by a coat of mucoprotein and lipid as with fowl plague and influenza viruses.
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Gottschalk, A. (1959). On the Mechanism Underlying Initiation of Influenza Virus Infection. In: Kikuth, W., Meyer, K.F., Nauck, E.G., Pappenheimer, A.M., Tomcsik, J. (eds) Ergebnisse der Mikrobiologie Immunitätsforschung und Experimentellen Therapie. Current Topics in Microbiology and Immunology, vol 32. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-42618-0_1
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