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Aconitase

[4.2.1.3 Citrat (Isocitrat)-Hydrolyase (Aconitat-Hydratase).]

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Enzyme

Part of the book series: Handbuch der Physiologisch- und Pathologisch-Chemischen Analyse ((HOPPE-SEYLER))

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Zusammenfassung

The enzyme which catalyses the equilibrium expressed by the reaction

was discovered by Martitts and Knoop 1 and named aconitase by Breusch 2. It has been suggested that two enzymes are concerned in catalysing this reaction3–8, but although aconitase has not been isolated in the pure state, the available evidence indicates that only a single enzyme is involved9–16. Recently, it has been established that of the four stereo¬isomers of isocitric acid only the dextrorotatory ls isomers occurs naturally17. (Lg corre¬sponds to the configuration of the a carbon of naturally occurring serine.)

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Authors and Affiliations

  1. Department of Biochemistry, John Curtin School of Medical Research, The Australian National University, Canberra, A.C.T., Australia

    John Francis Morrison

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  1. John Francis Morrison
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Editor information

R. A. Alberty G. Bratfisch F. H. Bruns R. Caputto F. Chatagner M. Chiga R. Czok R. Ehrenreich W. Franke H. Gibian D. M. Greenberg H. Hanson W. Hasselbach O. Hoffmann-Ostenhof B. Kassell K. N. v. Kaulla A. S. Keston H. Kröger A. Lajtha M. Laskowski Sr. M. Laskowski Jr. F. Leuthardt S. Lissitzky R. Michel J. F. Morrison R. J. Peanasky G. Pfleiderer G. W. E. Plaut H. Reinauer H. Schievelbein G. Siebert I. Trautschold M. F. Utter H.-H. Weber H. Weil-Malherbe E. Werle

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Morrison, J.F. (1967). Aconitase. In: Alberty, R.A., et al. Enzyme. Handbuch der Physiologisch- und Pathologisch-Chemischen Analyse. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-41177-3_20

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  • DOI: https://doi.org/10.1007/978-3-662-41177-3_20

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