Abstract
Carbon disulfide inhibits the activity of various enzymes in serum and in tissue both in vivo and in vitro [1,3–7]. We have examined the effect of small concentrations of CS2 on the metabolism of various drugs by the liver, since there has been a suggestion of interference [2]. We used hexobarbital-Na, aminophenazone, and procaine-HCl.
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Cohen, A.E., L.D. Scheel, J.F. Kopp, F.R. Stockell, R.G. Keenan, J.T. Mountain, and H.J. Paulus: Amer. Ind. Hyg. Ass. J. 20, 303 (1959).
Lazarev, N.V., Z. Labramovau. Z.C. Černy: Gig. Tr. prof. Zabol. 8, 24 (1965).
Mádlo, Z., and B. Soucek: Pracov. Lék. 5, 312 (1953).
Magistretti, M., e E. Peirone: Med. d. Lavoro 52, 1 (1961).
Peizker, Z.: Pracov. Lék. 6, 17 (1954).
Soucek, B., Z. Madlo u. H. Holeysovska: Arch. Gewerbepath. Gewerbehyg. 15, 531 (1957).
Wronska-Nofer, T., u. B. Kudlicka: Med. Pracy 16, 82 (1965).
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© 1969 Springer-Verlag Berlin Heidelberg
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Freundt, K.J., Dreher, W. (1969). Inhibition of Drug Metabolism by small Concentrations of Carbon Disulfide / Hemmung des Arzneimittelstoffwechsels durch geringe Schwefelkohlen-Stoffkonzentrationen. In: Habermann, E., et al. Naunyn Schmiedebergs Archiv für Pharmakologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-39718-3_75
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DOI: https://doi.org/10.1007/978-3-662-39718-3_75
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