Summary
In conscious, moderately hydrated female rabbits the effect of NaCl, L-alanine, L-serine, L-cysteine, 2, 3-dimercapto-l-propanol, S-(2-aminoethyl)-isothiouronium, Na2S2O3, S-methyl-L-cysteine and D-penicillamine upon renal secretion of water and osmotically active substance was investigated.
All compounds, except NaCl, L-alanine and L-serine, caused a decrease of urine volume and an increase of osmolarity.
The effect is similar to that of the antidiuretic hormone and is dependent upon the presence of the SH-group.
Auszugsweise vorgetragen auf der 9. Frühjahrstagung der Dtsch. Pharmakol. Ges., 10.-13. 3. 1968 in Mainz.
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Schmid, A. (1969). Wirkung von Thiolen auf Harnvolumen und -osmolarität beim Kaninchen. In: Habermann, E., et al. Naunyn Schmiedebergs Archiv für Pharmakologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-39718-3_178
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DOI: https://doi.org/10.1007/978-3-662-39718-3_178
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