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Die Lokalisation von atemsynchron entladenden Neuronen in der retikulären Formation des Hirnstammes der Katze unter verschiedenen experimentellen Bedingungen

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Naunyn Schmiedebergs Archiv für Pharmakologie

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Summary

Localization and discharge pattern of respiratory neurons in the pontine and the medullary reticular formation were studied in both pentobarbital anesthetized cats and in cats immobilized with Flaxedil.

  1. 1.

    In both preparations inspiratory, expiratory and another broader group of neurons not so clearly related to respiratory phases were scattered and intermingled throughout the medullary reticular formation.

  2. 2.

    Respiratory neurons in the pontine reticular formation were detected in vagotomized and immobilized cats but not in cats under pentobarbital anesthesia.

  3. 3.

    Expiratory neurons and another broader group of respiratory neurons were found more frequently in immobilized cats than in anesthetized cats.

  4. 4.

    Comparisons of discharge patterns of respiratory neurons in both preparations indicated that the activity patterns of neurons were influenced by the experimental conditions.

Localization of respiratory neurons in the medulla and the pons in relation to the localization of respiratory centers are discussed.

Zusammenfassung

Es wurden die Lokalisation und das Aktivitätsmuster respiratorischer Einheiten in der Substantia reticularis bulbi et pontis an Pentobarbital-narkotisierten, spontan atmenden und an Gallamin-immobilisierten, künstlich beatmeten Katzen unter Lokalanaesthesie untersucht.

  1. 1.

    An beiden Präparationen waren in der Substantia reticularis bulbi die respiratorischen Einheiten diffus verteilt und untereinander gemischt.

  2. 2.

    In der Substantia reticularis pontis ließen sich zahlreiche respiratorische Einheiten an der immobilisierten und vagotomierten Katze, jedoch nicht am narkotisierten Tier ableiten.

  3. 3.

    Exspiratorische und zwei Typen von „phase-spanning“-Einheiten wurden wesentlich häufiger in der Medulla immobilisierter Katzen als bei narkotisierten Katzen gefunden.

  4. 4.

    Der Vergleich der Aktivitätsmuster von Einheiten immobilisierter und narkotisierter Katzen zeigte, daß das Entladungsmuster der respiratorischen Einheiten durch diese unterschiedlichen Versuchsbedingungen weitgehend beeinflußt werden kann.

Die Verteilung respiratorischer Einheiten in der Substantia reticularis der Medulla und des Pons sowie die Zusammenhänge zwischen Funktion und spontanem Entladungsmuster respiratorischer Neurone werden besonders im Hinblick auf die Lokalisation des „Atemzentrums“ diskutiert.

Herrn Prof. Dr. L. Lendle zum 70. Geburtstag gewidmet.

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Author information

Authors and Affiliations

  1. Pharmakologisches Institut, Universität Tokyo, Tokyo, Japan

    Prof. Dr. T. Hukuhara Jr., Y. Saji, N. Kumadaki, H. Kojima, H. Tamaki, R. Takeda & F. Sakai

  2. Department of Pharmacology Faculty of Medicine, University of Tokyo, Tokyo, Japan, Bunkyo-ku

    Prof. Dr. T. Hukuhara Jr.

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  1. Prof. Dr. T. Hukuhara Jr.
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  2. Y. Saji
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  3. N. Kumadaki
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  4. H. Kojima
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  5. H. Tamaki
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  6. R. Takeda
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  7. F. Sakai
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Editor information

Editors and Affiliations

  1. Gießen, Deutschland

    E. Habermann

  2. Berlin, Deutschland

    H. Herken

  3. Frankfurt/M., Deutschland

    P. Holtz

  4. Graz, Österreich

    F. Lembeck

  5. Würzburg, Deutschland

    U. Trendelenburg

  6. Ulm, Deutschland

    L. Heilmeyer

  7. Göttingen, Deutschland

    L. Lendle

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© 1969 Springer-Verlag Berlin Heidelberg

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Hukuhara, T. et al. (1969). Die Lokalisation von atemsynchron entladenden Neuronen in der retikulären Formation des Hirnstammes der Katze unter verschiedenen experimentellen Bedingungen. In: Habermann, E., et al. Naunyn Schmiedebergs Archiv für Pharmakologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-39718-3_163

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  • DOI: https://doi.org/10.1007/978-3-662-39718-3_163

  • Publisher Name: Springer, Berlin, Heidelberg

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