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Biochemie und Pathobiochemie pp 813–835Cite as

Endokrine Funktionen II: Zytokine

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Zusammenfassung

Zytokine werden von den meisten Körperzellen nach Stimulation synthetisiert und sezerniert. Sie wirken in der Regel lokal über Oberflächenrezeptoren und aktivieren Signaltransduktionskaskaden, die zu veränderter Genexpression, Stoffwechselaktivität, Zelldifferenzierung, Proliferation, Migration und Apoptose führen können. Unterschiedliche Zytokine können die gleiche Signaltransduktionskaskase aktivieren (Redundanz).Andererseits kann ein bestimmtes Zytokin auf verschiedene Zelltypen einwirken und unterschiedliche Antworten hervorrufen (Pleiotropie).

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Authors
  1. P. C. Heinrich
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  2. F. Schaper
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  3. A. Timmermann
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  4. A. S. Martens
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  5. U. Lehmann
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Editor information

Editors and Affiliations

  1. Institut für Biochemie, Genetik und Mikrobiologie, Universität Regensburg, Universitätsstraße 31, 93053, Regensburg, Deutschland

    Georg Löffler

  2. Hämatologisch-onkologische, Praxis am Isartor, Zweibrückenstraße 2, 80331, München, Deutschland

    Petro E. Petrides

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© 2003 Springer-Verlag Berlin Heidelberg

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Heinrich, P.C., Schaper, F., Timmermann, A., Martens, A.S., Lehmann, U. (2003). Endokrine Funktionen II: Zytokine. In: Löffler, G., Petrides, P.E. (eds) Biochemie und Pathobiochemie. Springer-Lehrbuch. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-06058-2_28

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  • DOI: https://doi.org/10.1007/978-3-662-06058-2_28

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-06059-9

  • Online ISBN: 978-3-662-06058-2

  • eBook Packages: Springer Book Archive

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