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Conservation of the Original X and Homology of the X-linked Genes in Placental Mammals

  • Chapter
Sex Chromosomes and Sex-Linked Genes

Part of the book series: Monographs on Endocrinology ((ENDOCRINOLOGY,volume 1))

Abstract

Comparative DNA values of various vertebrates considered in Chapter 3 have indicated the polyphyletic origin of vertebrate genomes. It appeared that a series of polyploidization of the original vertebrate genome occurred in ancient times. Once the chromosomal sex-determining mechanism was well established, the genome of that lineage was stabilized, and no further gene duplication by polyploidization was possible. Indeed, diverse species of placental mammals gave the identical DNA value of 7.0 × 10−9 mg per diploid nucleus. It then became apparent that in this class extensive speciation from a common ancestor was accomplished almost exclusively by allelic mutation of individual gene loci with little or no change in the total number of gene loci.

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  1. Department of Biology, City of Hope Medical, Duarte, Calif., USA

    Dr. Susumu Ohno

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  1. Dr. Susumu Ohno
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Ohno, S. (1966). Conservation of the Original X and Homology of the X-linked Genes in Placental Mammals. In: Sex Chromosomes and Sex-Linked Genes. Monographs on Endocrinology, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-88178-7_5

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  • DOI: https://doi.org/10.1007/978-3-642-88178-7_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-88180-0

  • Online ISBN: 978-3-642-88178-7

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