Abstract
The development of rapid methods to identify the etiology of various infectious diseases is an important objective. However, in the development and evaluation of vaccines, caution and prudence rather than rapidity are essential. The acceleration of vaccine development by so-called “crash programs” can prove to be disastrous.
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References
Barker LF, Chisari FV, McGrath PP, et al. (1973) Transmission of type B viral hepatitis to chimpanzees. J Infect Dis 127:648–662
Blumberg BS, Alter HJ, Visnich S (1965) A “new” antigen in leukemia sera. JAMA 191:541–546
Dane DS, Cameron CH, Briggs M (1970) Virus-like particles in serum of patients with Australia antigen-associated hepatitis. Lancet 1:695–698
Francis DP, Hadler SC, Thompson SE, et al. (1982) The prevention of hepatitis B with vaccine. Ann Intern Med 97:362–366
Gallo RC, Salahuddin SZ, Popovic M, et al. (1984) Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS. Science 224:550–552
Hilleman MR, Buynak EB, Roehm RR, et al. (1975) Purified and inactivated human hepatitis B vaccine: progress report. Am J Med Sci 270:401–403
Krugman S, Giles JP, Hammond J (1971) Viral hepatitis, type B (Ms-2 strain): studies on active immunization. JAMA 217:41–45
Maupas P, Goudeau A, Coursaget P, et al. (1976) Immunization against hepatitis B in man. Lancet 1:1367–1370
Prince AM (1968) An antigen detected in the blood during the incubation period of serum hepatitis. Proc Natl Acad Sci USA 60:814–821
Purcell RH, Gerin JL (1975) Hepatitis B subunit vaccine: a preliminary report of safety and efficacy tests in chimpansees. Am J Med Sci 270:395–399
Reesink HW, Brummelhnis EH, van Elven LJT, et al. (1978) The preparation and evaluation of a hepatitis B vaccine in the Netherlands. In: Vyas GN, Cohen SN, Schmidt R (eds) Franklin Institute, Philadelphia, p 714
Szmuness W, Stevens CE, Harley EJ, et al. (1980) Hepatitis B vaccine: demonstration of efficacy in a controlled clinical trial in a high risk population in the United States. N Engl J Med 303:833–841
United States Public Health Service Centers for Disease Control (1982) Hepatitis B vaccine safety: report of an inter-agency group. MMWR 31:465–467
United States Public Health Service Centers for Disease Control (1983) The safety of hepatitis B vaccine. MMWR 32:134–136
Vilmer E, Barre-Sinoussi F, Rouzioux C, et al. (1984) Isolation of new lymphotropic retrovirus from two siblings with hemophilia B, one with AIDS. Lancet 1:753–757
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© 1985 Springer-Verlag Berlin Heidelberg
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Krugman, S. (1985). Evaluation of Hepatitis B Vaccine. In: Habermehl, KO. (eds) Rapid Methods and Automation in Microbiology and Immunology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69943-6_2
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DOI: https://doi.org/10.1007/978-3-642-69943-6_2
Publisher Name: Springer, Berlin, Heidelberg
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