Abstract
The association of new methods of labelling with short-lived radio-isotopes and of visualisation “in vivo” of these labelled molecules by emission tomography allows study of the brain metabolism at different levels : fluid movements (cerebral blood-flow), metabolism (oxygen or glucose consumption), blood-brain barrier permeability, metabolism of drugs (receptor ligand interactions). The success of such investigations depends on the simultaneous availability of three technological development : production of the chosen radio-isotope ; the labelling procedure and the detection device.
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Comar, D., Mazière, M., Saudubray, J.M., Zarifian, E., Naquet, R. (1980). Positron-Emission Tomography and Cerebral Metabolism. In: Caillé, JM., Salamon, G. (eds) Computerized Tomography. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67513-3_32
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DOI: https://doi.org/10.1007/978-3-642-67513-3_32
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