Zusammenfassung
Die Cytologie des Magens ist eine Exfoliativcytologie. Die mikroskopische Untersuchung des sog. Magennüchterninhaltes auf Zellen, insbesondere auf Leukocyten, die durch die Magenschleimhaut in das Magenlumen ausgewandert sind, spielt keine diagnostische Rolle mehr. Diese Methode wurde in der 4. Auflage dieses Handbuches kurz dargestellt. Die geschichtliche Entwicklung der Exfoliativcytologie des Magens läßt sich in drei Abschnitte gliedern: 1. die bis ins letzte Jahrhundert zurückreichenden ersten Versuche, Zellmaterial von der Magenschleimhaut unter klinischen Bedingungen zu gewinnen und mikroskopisch zu untersuchen, 2. der systematische Ausbau einer klinischen Magencytologie und 3. die Entwicklung endoskopisch gezielter Entnahmetechniken.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
Literatur
Ackerman, N. B., Haldorsen, D. K., Tendick, F. H., Elslager, E. F.: Preparation and screening of aminoacridines for induction of lung tumor fluorescence in rats. J. med. Chem. 11, 315 (1968)
Arnold, W. T., Hampton, J., Olin, W., Glass, H., Carruth, C.: Gastric lesions including exfoliative cytology. A diagnostic approach. J. Amer. med. Ass. 173, 1117 (1960)
Ayre, J. E., Oren, B. G.: A new rapid method of stomach-cancer diagnosis: the gastric brush. Cancer (Philad.) 6, 1177 (1953)
Bach-Nielsen, P.: The value of gastric cytology in the diagnosis of mesenchymal tumors. Amer. J. dig. Dis. 11, 938 (1966)
Bastos, A. L.: Intravital fluorescence of tumor cells. 2nd int. Congr. exfol. Cytol., Paris 1965
Bastos, A. L., Madeira, F.: A simple device for exfoliative cytology of the stomach. Gut 5, 192 (1964)
Bautista, A., DeLuca, V. A., Jr.: Endoscopic photography, biopsy, and cytology of the esophagus and stomach with the olympus fiberesophagoscope. Gastroenterology 60, 294 (1971)
Bennington, J. L., Porus, R., Ferguson, B., Hannon, G.: Cytology of gastric sarcoid. Report of a case. Acta cytol. (Philad.) 12, 30 (1968)
Bertalanffy, L. v., Masin, M., Masin, F. A.: Use of acridine orange fluorescence technique in exfoliative cytology. Science 124, 1024 (1956)
Bingold, K., Brilmayer, C., Mack, A.: Die Atebrinausscheidung im Harn als Diagnostikum maligner Tumoren. Krebsarzt 10, 1 (1955)
Blanc, W. A.: Cytologic diagnosis of cytomegalic inclusion disease in gastric washings. Amer. J. clin. Path. 28, 46 (1957)
Boddington, M. M., Spriggs, A. I.: The epithelial cells in megaloblastic anaemias. J. clin. Path. 12, 228 (1959)
Brandborg, L. L., Taniguchi, L., Rubin, C. E.: (1) Is exfoliative cytology practical for more general use in the diagnosis of gastric cancer ? A simplified chymotrypsin technique. Cancer (Philad.) 14, 1074 (1961)
Brandborg, L. L., Taniguchi, L., Rubin, C. E.: (2) Exfoliative cytology in non-malignant conditions of the upper intestinal tract. Acta cytol. (Philad.) 5, 187 (1961)
Brandborg, L. L., Tankersley, C. B., Uyeda, F.: “Low” versus “high” concentration chymotrypsin in gastric exfoliative cytology. Gastroenterology 57, 500 (1969)
Cabré-Fiol, V., Garcia, R. O.: La biopsia exfoliativa en el diagnostico de la degeneration maligna del ulcus gástrica. Gastroenterologia (Basel) 86, 521 (1956)
Cabré-Fiol, V., Cladera, E. S., de Luna, J. S., Mota, A. P., Vilardell, F.: La citologie exfoliative par fibroendoscopie dans le diagnostique du cancer gastrique. 2e Congr. europ. endoscop. dig., Paris 1972
Conte, M., Conte-Marti, M.: Le cyto-diagnostic du cancer gastrique. Gastroenterologia (Basel) 85, 257 (1956)
Crespi, M., di Matteo, S.: The diagnosis of the carcinoma of the stomach in its early phase. Arch, franç. Mal. Appar. dig. 61, 285 (1972)
Debray, Ch., Housset, P., Martin, Et.: La gastrobiopsie dirigée par aspiration-section et le cyto-diagnostic dirigé dans le diagnostic du cancer gastrique. Sem. Hôp. Paris 40, 141 (1964)
Dyke, K. van, Lantz, C., Szustkiewicz, C.: Quinacrine: mechanisms of antimalarial action. Science 169, 492 (1970)
Fukuda, T., Shida, S., Takita, T., Sawada, Y.: Cytologic diagnosis of early gastric cancer by the endoscopic method with gastrofiberscope. Acta cytol. (Philad.) 11, 456 (1967)
Gardner, F. H.: Observations on the cytology of gastric epithelium in tropical sprue. J. Lab. clin. Med. 47, 529 (1956)
Georgii, A., Ostertag, H., Atay, Z., Seifert, E.: Komparative Auswertung von Cytologie und Histologie für die Erkennung des Magencarcinoms. Verh. dtsch. Gres. inn. Med. 78, 229 (1972)
Gibbs, D. D.: Exfoliative cytology of the stomach. London: Butterworth 1968
Grable, E., Zamchek, N., Jankelson, O., Shipp, F.: Nuclear size of cells in normal stomach, in gastric atrophy and in gastric cancer. Gastroenterology 32, 1104 (1957)
Graham, R. M., Rheault, M. H.: Characteristic cellular changes in epithelial cells in pernicious anaemia. J. Lab. clin. Med. 43, 235 (1954)
Heinkel, K., Landgraf, J.: Die bioptische Magenschleimhautuntersuchung. Bibl. gastroent. (Basel) 5, 67 (1962)
Henning, N.: Die Cytodiagnostik maligner Tumoren. Fol. haemat. (Lpz.) 70, 198 (1950)
Henning, N., Witte, S.: Über eine neue Methode zur Cytodiagnostik der Magenkrankheiten. Dtsch. med. Wschr. 77, 1 (1952)
Henning, N., Witte, S.: Das Gastrocytogramm und die Möglichkeiten einer mikroskopischen intravitalen Magendiagnostik. In: Der Magen und seine Krankheiten (Boller, R., Hrsg.), S. 244. Wien-Innsbruck: Urban u. Schwarzenberg 1954
Henning, N., Witte, S.: Atlas der gastroenterologischen Cytodiagnostik. Stuttgart: Thieme 1957, 2. Aufl. 1968
Henning, N., Witte, S., Bressel, D.: The cytologic diagnosis of tumors of the upper gastrointestinal tract (esophagus, stomach, duodenum). Acta cytol. (Philad.) 8, 121 (1964)
Inui, Y., Takasu, S., Sakita, T.: A comparative evaluation of histological and cytological diagnosis for detection of stomach carcinoma in its early stage. Proc. 2nd World Congr. gastrointest. Endoscop., Rome 1970
Kalvins, Z. A., Rhyne, A. L., Dixon, I. R., Girsh, S.: Analysis of cytologic findings in patients with gastric carcinoma. Acta cytol. (Philad.) 11, 312 (1967)
Kasugai, T.: Recent instrumental development of fibergastroscopes with a light guide system. Gastrointest. Endoscopy 15, 224 (1969)
Kasugai, T.: Gastric lavage cytology under direct observation with the fibergastroscope. In: Early gastric cancer (Murakami, T., Ed.), p. 207. Univ. Tokyo Press 1971
Kasugai, T., Kato, H., Takase, T., Tubouchi, M., Yagi, M., Yamaoka, Y., Ishibashi, Y., Hattori, T.: Diagnosis of gastric cancer, especially early gastric cancer: combined employment of endoscopic and cytologic examinations, and biopsy. Proc. 9th int.Cancer Congr., Tokyo 1966
Klayman, M. I., Massey, B. W.: Gastric cells in pernicious anemia. J. Lab. clin. Med. 44, 820 (1954)
Klayman, M. I., Massay, B. W., Pleticka, S., Balambos, J. T., Brandborg, L., Kirsner J. B., Palmer, W. L.: Cytologic diagnosis of gastric cancer by chymotrypsin lavage. Gastroenterology 29, 849 (1955)
Klinger, J., Katz, R.: Tetracycline fluorescence in the diagnosis of gastric carcinoma. Gastroenterology 41, 29 (1961)
Kobayashi, S., Prolla, J. C., Yagi, M.: Gastroscopic diagnosis of early gastric carcinoma based on japanese classification. Gastrointest. Endosc. 16, 92 (1969)
Kuru, M.: Atlas of early carcinoma of the stomach. Tokyo: Nakayama-Shoten 1966
Langr, F., Parizek, J., Hradsky, M., Vortel, V.: Die Aktivität der Esterase, der alkalischen Phosphatase und Aminopeptidase in der Magenschleimhaut bei einigen präkanzerösen Zuständen. Gastroenterologia (Basel) 104, 213 (1965)
Leitao, O., Glass, G. B. J.: Enzyme cytochemistry of the abraded gastric surface epithelium. Amer. J. dig. Dis. 16, 769 (1971)
Martinez, A. R.: Technik zur Entnahme von Zellen aus dem Speiseröhren-Magenabschnitt mittels einer neuen Methode der Zellenabschürfung und Ausspülung. In: Intern. Sympos. klin. Cytodiagnostik (Henning, N., Witte, S., Hrsg.), S. 171. Stuttgart: Thieme 1958
Miyake, T., Yamamoto, Y., Ariyoshi, J., Suzaki, T., Hajiro, K., Kuzuya, H.: The significance of class III cells in gastric cytology. Jap. Arch. int. Med. 16, 1 (1969)
Nieburgs, H. E.: Cytologic technics for office and clinic. New York-London: Grune and Stratton 1956
Nieburgs, H. E., Rubio, C., Oppenheim, A.: Early detection of gastric secretory deficiency by tubeless analysis and cytology. Amer. J. dig. Dis. 10, 485 (1965)
Okuda, S., Morii, T., Inui, H., Senda, N., Hosoi, S.: Biopsy and water-jet cytology by color television-fiberscope for diagnosis of early gastric cancer. Proc. 2nd World Congr. gastrointest. Endoscop. 1970. Padova: Piccin med. books 1972
Ostertag, H., Atay, Z., Georgii, A.: Ergebnisse kombinierter cytologisch-histologischer Untersuchung von gezielt entnommenen Biopsien bei malignen Neoplasien des Magens. In: Current status of early diagnosis in stomach cancer (Witte, S., Grunze, H., Grundman, E., Eds.) (im Druck)
Panico, F. G., Papanicolaou, G. N., Cooper, W. H.: Abrasive balloon for exfoliation of gastric cancer cells. J. Amer. med. Ass. 143, 1308 (1950)
Papanicolaou, G. N.: A new procedure for staining vaginal smears. Science 95, 438 (1942)
Papanicolaou, G. N., Cooper, W. H.: The cytology of the gastric fluid in the diagnosis of cancer of the stomach. J. nat. Cancer Inst. 7, 357 (1947)
Planteydt, H. T., Willighagen, R. G.: Enzyme histochemistry of gastric carcinoma. J. Path. Bact. 90, 393 (1965)
Prolla, J. C., Kobayashi, S., Kirsner, J.: Cytology of malignant lymphomas of the stomach. Acta cytol. (Philad.) 14, 291 (1970)
Peolla, J. C., Kobayashi, S., Yoshii, Y., Yamaoka, Y., Kasugai, T.: Diagnostic cytology of the stomach in gastric syphilis. Acta cytol. (Philad.) 14, 333 (1970)
Peolla, J. C., Xaviee, R. G., Kjesnee, J. B.: Morphology of exfoliated cells in benign gastric ulcer. Acta cytol. (Philad.) 15, 128 (1971)
Peolla, J. C., Xaviee, R. G., Kiesnee, J. B.: Exfoliative cytology in gastric ulcer. Gastroenterology 63, 33 (1972)
Peolla, J. C., Yoshii, Y., Xaviee, R. G., Kiesnee, J. B.: Direct vision cytology and biopsy of esophagus and stomach: cytologic and histo-pathologic correlations. Proc. 4th int. Congr. Cytol., London 1971
Rall, D. P., Loo, T., Lane, M., Kelly, M. G.: Appearence and persistence of fluorescent material in tumor tissue after tetracycline administration. J. nat. Cancer Inst. 19, 79(1957)
Raskin, H. F., Kiesnee, J. B., Palmer, W. L.: Exfoliative cytology of the gastro-intestinal tract. In: Modern trends in gastroenterology, 2nd series. London: Butterworth 1958
Raskin, H. F., Kiesnee, J. B., Palmer, W. L.: Role of exfoliative cytology in the diagnosis of cancer of the digestive tract. J. Amer. med. Ass. 169, 789 (1959)
Raskin, H. F., Pleticka, S.: Exfoliative cytology of the stomach. CA. Bull. Cancer Progr. 10, 82 (1960)
Raskin, H. F., Palmer, W. L., Kiesnee, J. B.: Benign and malignant exfoliated gastrointestinal mucosal cells. Morphologic characteristics. Arch. int. Med. 107, 872 (1961)
Reed, P. I., Raskin, H. F., Geaef, P. W.: Malignant melanoma of the stomach. J. Amer. med. Ass. 182, 298 (1962)
Richie, C., Lambling, A.: Analyse critique du cytodiagnostic gastrique à l’occasion de 163 cas personnels. Arch. Mal. Appar. dig. 47, 1163 (1958)
Rosenthal, M., Teaut, H. F.: The mucolytic action of papain for cell concentration in the diagnosis of gastric cancer. Cancer (Philad.) 4, 147 (1951)
Rubin, C. E.: Diagnosis of gastric malignancy in pernicious anaemia. Gastroenterology 29, 563 (1955)
Rubin, C. E., Massey, B. W.: Pre-operative diagnosis of gastric and duodenal malignant lymphoma by exfoliative cytology. Cancer (Philad.) 7, 271 (1954)
Rubin, C. E., Massey, B. W., Kiesnee, J. B., Palmer, W. L., Stonecyphee, D. D.: The clinical value of gastrointestinal cytologic diagnosis. Gastroenterology 25, 119 (1953)
Sabuei, R., Ando, T., Kakihana, M., Tabayashi, A., Yamada, T.: A selective proteolytic lavage method for the cytodiagnosis of early gastric cancer. Acta cytol. (Philad.) 11, 473 (1967)
Sakita, T., Kueoyanagi, S., Sano, R., Ogueo, Y., Takasu, S., Omoei, K., Misu, Y., Fukutomi, H., Tobayashi, K.: Endoscopic diagnosis of early gastric cancer. Proc. 9th int. Cancer Congr., Tokyo 1966
Schade, R. O. K.: Gastric cytology. London: Arnold 1960
Schümmeleedee, N., Ebschnee, K. J., Keogh, H. E.: Die Grundlage der differenten Fluorochromierung von Ribo- und Desoxyribonukleinsäure mit Acridinorange. Naturwissenschaften 44, 467 (1957)
Seeck-Hanssen, A.: Endoscopic brush cytology in the diagnosis of gastric disease. In: Current status of early diagnosis in stomach cancer (Witte, S., Geunze, H., Geundmann, E., Eds.) (im Druck)
Seeck-Hanssen, A., Maecusson, J., Liavag, I.: Endoscopic brush cytology in the diagnosis of gastric disease. Proc. 4th int. Congr. Cytol., London 1971
Shida, S.: Biopsy smear cytology with the fibergastroscope for direct observation. In: Early gastric cancer (Mueakami, T., Ed.), p. 233. Univ. Tokyo Press 1971
Shida, S., Kueosawa, T., Takita, T., Sawada, Y.: Cytological diagnosis of early gastric cancer by cell biopsy method with gastrofiberscope. Proc. 2nd int. Congr. exfoliat. Cytol., Paris 1965
Speengee, E., Witte, S., Schaden, M.: The differential diagnostic role of nuclear DNA content in gastric cytology. In: Current status of early diagnosis in stomach cancer (im Druck)
Stevenson, J.: The accuracy of fluorescence microscopy for the diagnosis of cancer. Acta cytol. (Philad.) 8, 224 (1964)
Taebel, D. W., Peolla, J. C., Kiesnee, J. B.: Exfoliative cytology in the diagnosis of stomach cancer. Ann. Intern. med. 63, 1018 (1965)
Uleeldee, H., Geaham, R. M., Meigs, J. V.: Further studies on the cytologic method in the problem of gastric cancer. Ann. Surg. 128, 422 (1948)
Wattenbeeg, L. W.: Histochemical study of aminopeptidase in metaplasia and carcinoma of the stomach. Arch. Path. 67, 281 (1959)
Wengee, J., Peneold, E.: An improved compressed air apparatus for exfoliative cytology of the stomach. Gastroenterology 59, 358 (1970)
Witte, S.: Die Cytologie des Magens. Verh. dtsch. Ges. inn. Med. 57, 260 (1951)
Witte, S.: Cytodiagnostik mit Hilfe einer Fluorochromierung in vivo. Verh. dtsch. Ges. inn. Med. 61, 254 (1955)
Witte, S.: Die Technik der zytologischen Untersuchung der Speiseröhre und des Magens. Bibl. gastroent. (Basel) 5, 93 (1962)
Witte, S.: Die Cytodiagnostik der chronischen Gastritis. Verh. 2. Weltkongr. Gastroenter., München 1962, Bd. II, 205. Basel: Karger 1963
Witte, S.: Vital- und Fluoreszenzmethoden in der klinischen Zytologie. Dtsch. med. Wschr. 92, 1777 (1967)
Witte, S.: Intravital fluorescent staining with acridine derivatives in cytodiagnosis of the upper gastrointestinal tract. 2nd int. Congr. exfol. Cytol., Paris 1965. Acta cytol. (Philad.) 12, 15 (1968)
Witte S.: Die Zytologie in der Frühdiagnose des gastrointestinalen Karzinoms. Fortbildungsk. prakt. Gastroent. (Erlangen 1969), 2, 12. Basel-München-New York: Karger 1970
Witte, S.: The results of cytology with the technique of the gastroscopic cell brush; in comparison with biopsy, endoscopy, and radiology. In: Current status of early diagnosis in stomach cancer (im Druck)
Witte, S., Beessel, D.: Kritische Auswertung der Tumorzelldiagnostik in Speiseröhre und Magen. In: Praktische Ergebnisse neuer klinischer Forschung (Henning, N., Hrsg.), S. 205. Stuttgart: Schattauer 1962
Witte, S., Bressel, D.: Die zytologische Diagnose des Ulcus ventriculi. Dtsch. med. Wschr. 90, 1100 (1965)
Wunderer, A., Witte, S.: Zur Anwendung der Interferenzkontrastmikroskopie in der Zytologie. Zeiss Informationen 16, 121 (1968)
Yamada, T.: Basic study of the proteolytic enzyme lavage method in the gastric diagnosis, especially in the comparative analysis of the exfoliative tendency of malignant and benign gastric epithelial cells. Acta cytol. (Philad.) 8, 19 (1964)
Yamagata, S., Ishioka, K., Yamagata, J.: The significance of the cytological examination in gastric mass survey. 4th Int. Congr. Cytol., London 1971
Yoshii, Y., Takahasi, J., Yamaoka, Y., Kasugai, T.: Significance of imprint smear in cytologic diagnosis of malignant tumors of the stomach. Acta cytol. (Philad.) 14, 249 (1970)
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1974 Springer-Verlag Berlin · Heidelberg
About this chapter
Cite this chapter
Witte, S. (1974). Cytologie des Magens. In: Berndt, H., et al. Magen. Handbuch der inneren Medizin, vol 3 / 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65881-5_8
Download citation
DOI: https://doi.org/10.1007/978-3-642-65881-5_8
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-65882-2
Online ISBN: 978-3-642-65881-5
eBook Packages: Springer Book Archive