Abstract
The spike gene of TGEV TH98 strain was translated into amino sequence by Editseq. The secondary structure and B cell epitope of spike protein of TGEV TH98 strain were predicted by Protean. Combining the results according to these methods, the spike protein of TGEV TH98 strain has complicated secondary structure. There are several epitopes of the B-cells in spike protein, including 43-56aa, 97-104aa, 117-128aa, 132-173aa, 238-257aa, 391-398aa, 535-706aa, 779-799aa, 918-987aa, 1165-1200aa, 1257-1266aa and 1430-1446aa.
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This work is supported by National High-Tech Research and Development Plan of China #2008AA10Z326 to Y Dai and National Natural Science Foundation of China #20776112 to S Jia.
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Yu, Tf., Shao, Sl., Xu, Xj., Lv, Jw., Li, M. (2012). Prediction of TGEV Spike Protein Secondary Structure and B Cell Epitopes. In: Zhu, E., Sambath, S. (eds) Information Technology and Agricultural Engineering. Advances in Intelligent and Soft Computing, vol 134. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27537-1_8
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DOI: https://doi.org/10.1007/978-3-642-27537-1_8
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