Skip to main content
SpringerLink
Log in

Treatment Considerations for Cancer Pain Syndromes

  • Chapter
  • First Online:
Essentials of Interventional Cancer Pain Management

  • 1535 Accesses

Abstract

When considering interventional therapeutic options for management of pain in the patient with cancer, active or in remission, thought must be given to the possibility of elevated risk about infection and bleeding complications. Concomitant therapy with anticoagulants or chemotherapeutic agents coupled with frequently frail physiology can elevate risk. When treating pain in those with cancer or a history of cancer – even in patients without active disease – close review of each patient’s laboratory data and medication list is always advisable.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Reference

  1. Deer TR, et al. Comprehensive consensus based guidelines on intrathecal drug delivery systems in the treatment of pain caused by cancer pain. Pain Physician. 2011;14:E283–312.

    PubMed  Google Scholar 

  2. Lin Y, Foltz LM. Proposed guidelines for platelet transfusion Issue. BCMJ. 2005;47(5):245–8.

    Google Scholar 

  3. Boehm S, Rothermundt C, Hess D, Joerger M. Antiangiogenic drugs in oncology: a focus on drug safety and the elderly – a mini-review. Gerontology. 2010;56:303–9.

    Article  CAS  PubMed  Google Scholar 

  4. Streiff MB. Diagnosis and initial treatment of venous thromboembolism in patients with cancer. J Clin Oncol. 2009;27:4889–94.

    Article  PubMed  Google Scholar 

  5. Terese T, Horlocker MD, et al. Regional anesthesia in the patient receiving antithrombotic or thrombolytic therapy-American Society of Regional Anesthesia and Pain Medicine Evidence-Based Guidelines (Fourth Edition). Reg Anesth Pain Med. 2018;43(2):263–309.

    Google Scholar 

  6. Malik B, Stillman M. Chemotherapy-induced peripheral neuropathy. Curr Neurol Neurosci Rep. 2008;8(1):56–65.

    Article  CAS  PubMed  Google Scholar 

  7. Quasthoff S, Hartung HP. Chemotherapy-induced peripheral neuropathy. J Neurol. 2002;249(1):9–17.

    Article  CAS  PubMed  Google Scholar 

  8. Chaudhry V, Eisenberger MA, Sinibaldi VJ, Sheikh K, Griffin JW, Cornblath DR. A prospective study of suramin-induced peripheral neuropathy. Brain. 1996;119(Pt 6):2039–52.

    Article  PubMed  Google Scholar 

  9. Loh J, Gulati A. The use of transcutaneous electrical nerve stimulation (TENS) in a major cancer center for the treatment of severe cancer-related pain and associated disability. Pain Med. 2013;16(6):1204–10.

    Article  PubMed  Google Scholar 

  10. Cata JP, Cordella JV, Burton AW, Hassenbusch SJ, Weng HR, Dougherty PM. Spinal cord stimulation relieves chemotherapy-induced pain: a clinical case report. J Pain Symptom Manag. 2004;27(1):72–8.

    Article  Google Scholar 

  11. Medtronic, Inc. MRI guidelines for Medtronic neurostimulation systems for chronic pain. Minneapolis: Medtronic, Inc; 2013.

    Google Scholar 

  12. Dellon AL, Swier P, Maloney CT Jr, Livengood MS, Werter S. Chemotherapy-induced neuropathy: treatment by decompression of peripheral nerves. Plast Reconstr Surg. 2004;114(2):478–83.

    Article  PubMed  Google Scholar 

  13. Vera Llonch M, Oster G, Hagiwara M, Sonis S. Oral mucositis in patients undergoing radiation treatment for head and neck carcinoma. Cancer. 2006;106(2):329–36.

    Article  PubMed  Google Scholar 

  14. Rosenthal DI, Trotti A. Strategies for managing radiation-induced mucositis in head and neck cancer. In: Seminars in radiation oncology (Vol. 19, No. 1, pp. 29–34). WB Saunders; 2009.

    Google Scholar 

  15. Ruggiero S, Gralow J, Marx RE, Hoff AO, Schubert MM, Huryn JM, et al. Practical guidelines for the prevention, diagnosis, and treatment of osteonecrosis of the jaw in patients with cancer. J Oncol Pract. 2006;2(1):7–14.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Jereczek-Fossa BA, Orecchia R. Radiotherapy-induced mandibular bone complications. Cancer Treat Rev. 2002;28(1):65–74.

    Article  PubMed  Google Scholar 

  17. Erdine S, Racz G, Noe C. Somatic blocks of the head and neck. In: Raj P, et al., editors. Interventional pain management, image-guided procedures. Philadelphia: Saunders; 2008.

    Google Scholar 

  18. Candido K, Batra M. Nerve blocks of the head and neck. In: Benzon H, et al., editors. Raj’s practical management of pain. Philadelphia: Mosby; 2008.

    Google Scholar 

  19. Stubblefield MD. Radiation fibrosis syndrome: neuromuscular and musculoskeletal complications in cancer survivors. PM&R. 2011;3(11):1041–54.

    Article  Google Scholar 

  20. Dolly JO, Aoki KR. The structure and mode of action of different botulinum toxins. Eur J Neurol. 2006;12(Suppl 4):1–9.

    Article  Google Scholar 

  21. Stubblefield MD, Levine A, Custodio CM, Fitzpatrick T. The role of botulinum toxin type A in the radiation fibrosis syndrome: a preliminary report. Arch Phys Med Rehabil. 2008;89(3):417–21.

    Article  PubMed  Google Scholar 

  22. Sarin A, Safar B. Management of radiation proctitis. Gastroenterol Clin N Am. 2013;42(4):913–25.

    Article  Google Scholar 

  23. Kurdali B, Sterban S, Siefferman J. Spinal cord stimulator lead placement via sacral hiatus in the treatment of post radiation proctitis. 16th annual North American neuromodulation society. From innovation to reality. 2012.

    Google Scholar 

  24. Krames E. Spinal cord stimulation: indications, mechanism of action, and efficacy. Curr Rev Pain. 1999;3(6):419–26.

    Article  CAS  PubMed  Google Scholar 

  25. Hunter C, Dave N, Diwan S, Deer T. Neuromodulation of pelvic visceral pain: review of the literature and case series of potential novel targets for treatment. Pain Pract. 2013;13(1):3–17.

    Article  PubMed  Google Scholar 

  26. Delanian S, Lefaix JL, Pradat PF. Radiation-induced neuropathy in cancer survivors. Radiother Oncol. 2012;105(3):273–82.

    Article  PubMed  Google Scholar 

  27. Delanian S, et al. Radiation-induced neuropathy in cancer survivors. Radiother Oncol. 2012;105:273–82.

    Article  PubMed  Google Scholar 

  28. Pfeilschifter J, Diel IJ. Osteoporosis due to cancer treatment: pathogenesis and management. J Clin Oncol. 2000;18(7):1570–93.

    Article  CAS  PubMed  Google Scholar 

  29. Lustberg MB, Reinbolt RE, Shapiro CL. Bone health in adult cancer survivorship. J Clin Oncol. 2012;30(30):3665–74. https://doi.org/10.1200/JCO.2012.42.2097. Epub 2012 Sep 24

    Article  CAS  PubMed  Google Scholar 

  30. Schiff D, Jensen ME. Kyphoplasty in cancer: an encouraging step. Lancet Oncol. 2011;12(3):202–3. https://doi.org/10.1016/S1470-2045(11)70032-8.

    Article  PubMed  Google Scholar 

  31. Burton AW, Mendel E. Vertebroplasty and kyphoplasty. Pain Physician. 2003;6:335–43. I

    PubMed  Google Scholar 

  32. Hoh BL, Rabinov JD, Pryor JC, Hirsch JA. Balloon kyphoplasty for vertebral compression fracture using a unilateral balloon tamp via a uni-pedicular approach: technical note. Pain Physician. 2004;7:111–4.

    PubMed  Google Scholar 

  33. Melvin Hu M, Eskey CJ, Tong SC, Nogueira RG, Pomerantz SR, Rabinov JD, Pryor JC, Hirsch JA. Kyphoplasty for vertebral compression fracture via a uni-pedicular approach. Pain Physician. 2005;8:363–7.

    PubMed  Google Scholar 

  34. Cho CH, Mathis JM, Ortiz O. Sacral fractures and sacroplasty. Neuroimaging Clin N Am. 2010;20:179–86.

    Article  PubMed  Google Scholar 

  35. Shah RV. Sacral kyphoplasty for the treatment of painful sacral insufficiency fractures and metastases. Spine J. 2012;12(2):113–20.

    Article  PubMed  Google Scholar 

  36. Burton AW, Fanciullo GJ, Beasley RD, Fisch MJ. Chronic pain in the cancer survivor: a new frontier. Pain Med. 2007;8(2):189–98.

    Article  PubMed  Google Scholar 

  37. Stubblefield MD, Keole N. Upper body pain and functional disorders in patients with breast cancer. PM&R. 2013;6:170–83.

    Article  Google Scholar 

  38. Rajput K. Painful neuromas. Clin J Pain. 2012;28(7):639–45.

    Article  PubMed  Google Scholar 

  39. Friedman T, Adler R. Sonographically guided cryoneurolysis: preliminary experience and clinical outcomes. Ultrasound Med. 2012;31(12):2025–34.

    Article  Google Scholar 

  40. Rathmell JP. Atlas of image-guided intervention in regional anesthesia and pain medicine. Philadelphia: Lippincott Williams & Wilkins; 2011.

    Google Scholar 

  41. Hardy PA. Anatomical variation in the position of the proximal intercostal nerve. Br J Anaesth. 1988;61:338–9.

    Article  CAS  PubMed  Google Scholar 

  42. Byas-Smith MG, Gulati A. Ultrasound-guided intercostal nerve cryoablation. Anesth Analg. 2006;103(4):1033–5.

    Article  PubMed  Google Scholar 

  43. Karmakar MK. Ultrasound-guided thoracic paravertebral block. In: Atlas of ultrasound-guided procedures in interventional pain management. New York: Springer; 2011. p. 133–48.

    Chapter  Google Scholar 

  44. Freynet A, Falcoz PE. Is transcutaneous electrical nerve stimulation effective in relieving postoperative pain after thoracotomy? Interact Cardiovasc Thorac Surg. 2010;10(2):283–8.

    Article  PubMed  Google Scholar 

  45. Tremont-Lukats IW, Teixeira GM, Backonja MM. Systemic administration of local anesthetic agents to relieve neuropathic pain. Cochrane Database of Systematic Reviews. 2005

    Google Scholar 

  46. Fishman SM. Bonica’s management of pain. Philadelphia: Lippincott Williams & Wilkins; 2012.

    Google Scholar 

  47. Visser E, Schug SA. The role of ketamine in pain management. Biomed Pharmacother. 2006;60(7):341–8.

    Article  CAS  PubMed  Google Scholar 

  48. Graybill J, Conermann T, Kabazie AJ, Chandy S. Spinal cord stimulation for treatment of pain in a patient with post thoracotomy pain syndrome. Pain Physician. 2011;14:441–5.

    PubMed  Google Scholar 

  49. Wininger KL, Bester ML, Deshpande KK. Spinal cord stimulation to treat postthoracotomy neuralgia: non–small-cell lung cancer: a case report. Pain Manag Nurs. 2012;13(1):52–9.

    Article  PubMed  Google Scholar 

  50. Borsje S, Bosmans JC, Vander Schans CP, Geertzen JHB, Dijkstra PU. Phantom pain: a sensitivity analysis. Disabil Rehabil. 2004;26(14–15):905–10.

    Article  CAS  PubMed  Google Scholar 

  51. Cohen SP, Gambel JM, Raja SN, Galvagno S. The contribution of sympathetic mechanisms to postamputation phantom and residual limb pain: a pilot study. J Pain. 2011;12(8):859–67.

    Article  PubMed  Google Scholar 

  52. Ilfeld BM, Moeller-Bertram T, Hanling SR, Tokarz K, Mariano ER, Loland VJ, Wallace MS. Treating intractable phantom limb pain with ambulatory continuous peripheral nerve blocks: a pilot study. Pain Med. 2013;14(6):935–42.

    Article  PubMed  Google Scholar 

  53. Kern U, Martin C, Scheicher S, Müller H. Botulinum toxin type A influences stump pain after limb amputations. J Pain Symptom Manag. 2003;26(6):1069–70.

    Article  Google Scholar 

  54. Wu H, Sultana R, Taylor KB, Szabo A. A prospective randomized double-blinded pilot study to examine the effect of botulinum toxin type A injection versus lidocaine/depomedrol injection on residual and phantom limb pain: initial report. Clin J Pain. 2012;28(2):108.

    Article  CAS  PubMed  Google Scholar 

  55. Nielson KD, Adams JE, Hosobuchi Y. Phantom limb pain: treatment with dorsal column stimulation. J Neurosurg. 1975;42:301–7.

    Article  CAS  PubMed  Google Scholar 

  56. Viswanathan A, Phan PC, Burton AW. Use of spinal cord stimulation in the treatment of phantom limb pain: case series and review of the literature. Pain Pract. 2010;10(5):479–84.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Austin Interventional Pain, Austin, TX, USA

    Devin Peck (Physician)

  2. Eagle Consulting Services, White Plains, NY, USA

    Gendai J. Echezona

Authors
  1. Devin Peck
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Gendai J. Echezona
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Gendai J. Echezona .

Editor information

Editors and Affiliations

  1. Department of Anesthesiology and Critical Care, Memorial Sloan Kettering Cancer Center, New York, NY, USA

    Amitabh Gulati

  2. Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA

    Vinay Puttanniah

  3. Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston, TX, USA

    Brian M. Bruel

  4. Midwest Neuroscience Institute, Center for the Relief of Pain, Kansas City, MO, USA

    William S. Rosenberg

  5. Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA

    Joseph C. Hung

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Peck, D., Echezona, G.J. (2019). Treatment Considerations for Cancer Pain Syndromes. In: Gulati, A., Puttanniah, V., Bruel, B., Rosenberg, W., Hung, J. (eds) Essentials of Interventional Cancer Pain Management. Springer, Cham. https://doi.org/10.1007/978-3-319-99684-4_21

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-99684-4_21

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-99682-0

  • Online ISBN: 978-3-319-99684-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation