Abstract
Erythromelalgia is a rare disorder of the extremities in which there is burning pain that is frequently aggravated by heat or by lowering the extremity. This is the first human disorder in which an ion channel mutation (Na(v) 1.7) is associated with chronic neuropathic pain. This chapter discusses the fundamental pathogenesis, types of Erythromelalgia, clinical findings, and treatment modalities for Erythromelalgia.
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References
Drenth JP, van Genderen PJ, Michiels JJ. Thrombocythemic erythromelalgia, primary erythermalgia, and secondary erythermalgia: three distinct clinicopathologic entities. Angiology. 1994;45(6):451–3.
Alhadad A, Wollmer P, Svensson A, Eriksson KF. Erythromelalgia: incidence and clinical experience in a single centre in Sweden. Vasa. 2012;41:43–8.
Reed KB, Davis MD. Incidence of erythromelalgia: a population-based study in Olmsted County, Minnesota. J Eur Acad Dermatol Venereol. 2009;23:13–5.
Russo R, Caroleo MC, Cione E, Perri M, Paparo MT, et al. Dual effect of ziconotide in primary erythromelalgia. Case Rep Med. 2015;2015:592170.
Matzke LL, Lamer TJ, Gazelka HM. Spinal cord stimulation for treatment of neuropathic pain associated with erythromelalgia. Reg Anesth Pain Med. 2016;41:619–20.
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Gulve, A. (2019). Erythromelalgia. In: Abd-Elsayed, A. (eds) Pain. Springer, Cham. https://doi.org/10.1007/978-3-319-99124-5_271
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DOI: https://doi.org/10.1007/978-3-319-99124-5_271
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