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Sellar Region

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Central Nervous System Intraoperative Cytopathology

Part of the book series: Essentials in Cytopathology ((EICP,volume 13))

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Abstract

Pituitary specimens are frequently submitted for an intraoperative diagnosis being one of the most commonly handled neurosurgical specimens. Common indications for intraoperative assessment of sellar region lesions include the following: (1) ensure an appropriate tissue allocation and processing for accurate diagnosis, (2) confirm the presence of pituitary adenoma, (3) distinguish pituitary adenoma from other regional lesions, and (4) identify an unexpected lesion. Due to the peculiar location of the pituitary gland, just above the sphenoid sinus, a transnasal surgical approach is the rout by which biopsy or excision of most sellar lesions is performed. Because specimens obtained by this technique are slippery tiny fragments, cytologic preparations play a crucial diagnostic role on pituitary intraoperative consultation. In this chapter, the cytomorphologic features and differential diagnosis of neoplastic and nonneoplastic processes involving the pituitary gland/sellar region are revised.

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Authors and Affiliations

  1. Professor of Pathology, Complutense University School of Medicine, Madrid, Spain

    César R. Lacruz

  2. Professor of Pathology, University Hospital Extremadura, Medical School, Badajoz, Spain

    Javier Saénz de Santamaría

  3. Pathologist, Director Ultrasound-guided Fine Needle Aspiration Service, Outpatient Pathology Associates / Precision Pathology, Sacramento, CA, USA

    Ricardo H. Bardales

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  1. César R. Lacruz
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  2. Javier Saénz de Santamaría
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  3. Ricardo H. Bardales
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Lacruz, C.R., Saénz de Santamaría, J., Bardales, R.H. (2018). Sellar Region. In: Central Nervous System Intraoperative Cytopathology. Essentials in Cytopathology, vol 13. Springer, Cham. https://doi.org/10.1007/978-3-319-98491-9_22

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  • DOI: https://doi.org/10.1007/978-3-319-98491-9_22

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-98490-2

  • Online ISBN: 978-3-319-98491-9

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