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Lumbar En Bloc Resection

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Spinal Tumor Surgery

Abstract

En bloc resection is a surgical procedure aiming to remove a tumor mass in its entirety, fully covered by a continuous shell of healthy tissue. Oncological indications for this procedure are aggressive benign tumors (Enneking stage 3), like osteoblastoma and giant-cell tumor, and low-grade malignant tumors (Enneking stage IA and B), like chordoma and chondrosarcoma. In high-grade malignant tumors like osteosarcoma and Ewing sarcoma, en bloc resection must be combined with protocols of chemotherapy and radiotherapy (RT) in a multidisciplinary approach. En bloc resection can be an option in selected single metastases originating from tumors resistant to chemotherapy and radiation protocols, once the criteria of feasibility are fulfilled without functional sacrifices. The criteria of feasibility of tumor-free margins in the lumbar spine include one pedicle free from tumor and a part of the posterior arch allowing room to release the thecal sac. The Weinstein-Boriani-Biagini (WBB) staging system can be helpful in providing standardized strategies according to tumor extension and location. A strong consideration of the role of margins in the local and systemic prognosis can include in the en bloc resection even relevant anatomical structures (nerve roots, dura, arteries, and veins) when they are infiltrated by the tumor or are running along the tumor margins.

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References

  1. Enneking WF. Muscoloskeletal tumor surgery. New York: Churchill Livingstone; 1983. p. 69–122.

    Google Scholar 

  2. Simon MA. Surgical Margins. In: Simon MA, Springfield D, editors. Surgery for bone and soft tissue Tumors. Philadelphia: Lippincott-Raven; 1998. p. 77–92.

    Google Scholar 

  3. Talac R, Yaszemski MJ, Currier BL, Fuchs B, Dekutoski MB, Kim CW, et al. Relationship between surgical margins and local recurrence in sarcomas of the spine. Clin Orthop Relat Res. 2002;397:127–32.

    Article  Google Scholar 

  4. Rosen G. Pre-operative (neo-adjuvant) chemotherapy for osteogenic sarcoma: a ten years experience. Orthopedics. 1985;8:659–70.

    CAS  PubMed  Google Scholar 

  5. Lador R, Gasbarrini A, Gambarotti M, Bandiera S, Ghermandi R, Boriani S. Surgeon’s perception of margins in spinal en bloc resection surgeries: how reliable is it? Eur Spine J. 2017 Feb 6; https://doi.org/10.1007/s00586-017-4967-0. [Epub ahead of print].

    Article  Google Scholar 

  6. Boriani S, Weinstein JN. The role of “tumor-free margins” in the resection of spinal Tumors: who should be treating spine tumors? Semin Spine Surg. 2009;21:76–85.

    Article  Google Scholar 

  7. Fisher CG, Saravanja DD, Dvorak MF, Rampersaud YR, Clarkson PW, Hurlbert J, et al. Surgical management of primary bone tumors of the spine: validation of an approach to enhance cure and reduce local recurrence. Spine. 2011;36(10):830–6.

    Article  Google Scholar 

  8. Biagini R, Casadei R, Boriani S, Erba F, Sturale C, Mascari C, et al. En bloc vertebrectomy and dural resection for chordoma: a case report. Spine. 2003;28(18):E368–72.

    Article  Google Scholar 

  9. Rhines LD, Fourney DR, Siadati A, Suk I, Gokaslan ZL. En bloc resection of multilevel cervical chordoma with C-2 involvement: case report and description of operative technique. J Neurosurg Spine. 2005;2(2):199–205.

    Article  Google Scholar 

  10. Bailey CS, Fisher CG, Boyd MC, Dvorak MF. En bloc marginal excision of a multilevel cervical chordoma: case report. J Neurosurg Spine. 2006;4(5):409–14.

    Article  Google Scholar 

  11. Keynan O, Fisher CG, Boyd MC, O'Connell JX, Dvorak MF. Ligation and partial excision of the cauda equina as part of a wide resection of vertebral osteosarcoma: a case report and description of surgical technique. Spine. 2005;30(4):E97–E102.

    Article  Google Scholar 

  12. Murakami H, Tomita K, Kawahara N, Oda M, Yahata T, Yamaguchi T. Complete segmental resection of the spine, including the spinal cord, for telangiectatic osteosarcoma: a report of 2 cases. Spine. 2006;31(4):E117–22.

    Article  Google Scholar 

  13. Druschel C, Disch AC, Melcher I, Engelhardt T, Luzzati A, Haas NP, et al. Surgical management of recurrent thoracolumbar spinal sarcoma with 4-level total en bloc spondylectomy: description of technique and report of two cases. Eur Spine J. 2012;21(1):1–9.

    Article  Google Scholar 

  14. Boriani S, Saravanja D, Yamada Y, Varga PP, Biagini R, Fisher CG. Challenges of local recurrence and cure in low grade malignant tumors of the spine. Spine. 2009;34(22 Suppl):S48–57.

    Article  Google Scholar 

  15. Boriani S, Bandiera S, Donthineni R, Amendola L, Cappuccio M, De Iure F, et al. Morbidity of en bloc resections in the spine. Eur Spine J. 2010;19(2):231–41.

    Article  Google Scholar 

  16. Falicov A, Fisher CG, Sparkes J, Boyd MC, Wing PC, Dvorak MF. Impact of surgical intervention on quality of life in patients with spinal metastases. Spine. 2006;31(24):2849–56.

    Article  Google Scholar 

  17. Patchell RA, Tibbs PA, Regine WF, Payne R, Saris S, Kryscio RJ, et al. Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: a randomised trial. Lancet. 2005;366(9486):643–8.

    Article  Google Scholar 

  18. Yao KC, Boriani S, Gokaslan ZL, Sundaresan N. En bloc spondylectomy for spinal metastases: a review of techniques. Neurosurg Focus. 2003;15(5):E6.

    PubMed  Google Scholar 

  19. Tomita K, Kawahara N, Kobayashi T, Yoshida A, Murakami H, Akamaru T. Surgical strategy for spinal metastases. Spine. 2001;26(3):298–306.

    Article  CAS  Google Scholar 

  20. Li H, Gasbarrini A, Cappuccio M, Terzi S, Paderni S, Mirabile L, et al. Outcome of excisional surgeries for the patients with spinal metastases. Eur Spine J. 2009;18(10):1423–30.

    Article  Google Scholar 

  21. Stener B, Johnsen OE. Complete removal of three vertebrae for giant-cell tumour. J Bone Joint Surg Br. 1971;53(2):278–87.

    Article  CAS  Google Scholar 

  22. Stener B. Complete removal of vertebrae for extirpation of tumors. Clin Orthop Relat Res. 1989;245:72–82.

    Google Scholar 

  23. Roy-Camille R, Saillant G, Bisserie´ M, et al. Resection vertebrale totale dans la chirurgie tumorale au niveau du rachis dorsal par voie posterieure pure. Rev Chir Orthop. 1981;67:421–30.

    CAS  PubMed  Google Scholar 

  24. Tomita K, Kawahara N, Baba H, Tsuchiya H, Fujita T, Toribatake Y. Total en bloc spondylectomy. A new surgical technique for primary malignant vertebral tumors. Spine. 1997;22(3):324–33.

    Article  CAS  Google Scholar 

  25. Boriani S, Weinstein JN, Biagini R. Primary bone tumors of the spine. Terminology and surgical staging. Spine. 1997;22(9):1036–44.

    Article  CAS  Google Scholar 

  26. Hart RA, Boriani S, Biagini R, Currier B, Weinstein JN. A system for surgical staging and management of spine tumors. A clinical outcome study of giant cell tumors of the spine. Spine. 1997;22:1773–83.

    Article  CAS  Google Scholar 

  27. Chan P, Boriani S, Fourney DR, Biagini R, Dekutoski MB, Fehlings MG, et al. An assessment of the reliability of the Enneking and Weinstein-Boriani-Biagini classifications for staging of primary spinal tumors by the spine oncology study group. Spine. 2009;34(4):384–91.

    Article  Google Scholar 

  28. Boriani S. Subtotal and total vertebrectomy for tumours. In: Surgical techniques in orthopedics and traumatology. 55-070-A. Paris: Editions Scientifiques et Medicales Elsevier; 2000.

    Google Scholar 

  29. Kawahara N, Tomita K, Baba H, Toribatake Y, Fujita T, Mizuno K, et al. Cadaveric vascular anatomy for total en bloc spondylectomy in malignant vertebral tumors. Spine. 1996;21(12):1401–7.

    Article  CAS  Google Scholar 

  30. Gasbarrini A, Simoes CE, Bandiera S, Amendola L, Barbanti Brodano G, Cappuccio M, et al. Influence of a thread wire saw guide and spinal cord protector device in “en bloc” vertebrectomies. J Spinal Disord Tech. 2012;25(2):E7–12.

    Article  Google Scholar 

  31. Roy-Camille R, Mazel CH, Saillant G, Lapresle PH. Treatment of malignant tumors of the spine with posterior instrumentation. In: Sundaresan N, Schmidek HH, Schiller AL, Rosenthal DI, editors. Tumors of the spine. Diagnosis and clinical management. Philadelphia: W.B.Saunders; 1990. p. 473–92.

    Google Scholar 

  32. Murakami H, Kawahara N, Tomita K, Demura S, Kato S, Yoshioka K. Does interruption of the artery of Adamkiewicz during total en bloc spondylectomy affect neurologic function? Spine. 2010;35(22):E1187–92.

    Article  Google Scholar 

  33. Fujimaki Y, Kawahara N, Tomita K, Murakami H, Ueda Y. How many ligations of bilateral segmental arteries cause ischemic spinal cord dysfunction? An experimental study using a dog model. Spine. 2006;31(21):E781–9.

    Article  Google Scholar 

  34. Kato S, Kawahara N, Tomita K, Murakami H, Demura S, Fujimaki Y. Effects on spinal cord blood flow and neurologic function secondary to interruption of bilateral segmental arteries which supply the artery of Adamkiewicz: an experimental study using a dog model. Spine. 2008;33(14):1533–41.

    Article  Google Scholar 

  35. Ueda Y, Kawahara N, Tomita K, Kobayashi T, Murakami H, Nambu K. Influence on spinal cord blood flow and function by interruption of bilateral segmental arteries at up to three levels: experimental study in dogs. Spine. 2005;30(20):2239–43.

    Article  Google Scholar 

  36. Kawahara N, Tomita K, Kobayashi T, Abdel-Wanis ME, Murakami H, Akamaru T. Influence of acute shortening on the spinal cord: an experimental study. Spine. 2005;30(6):613–20.

    Article  Google Scholar 

  37. Fisher CG, Andersson GB, Weinstein JN. Spine focus issue. Summary of management recommendations in spine oncology. Spine. 2009;34(22 Suppl):S2–6.

    Article  Google Scholar 

  38. Harrop JS, Schmidt MH, Boriani S, Shaffrey CI. Aggressive “benign” primary spine neoplasms: osteoblastoma, aneurysmal bone cyst, and giant cell tumor. Spine. 2009;34(22 Suppl):S39–47.

    Article  Google Scholar 

  39. Schwab J, Gasbarrini A, Bandiera S, Boriani L, Amendola L, Picci P, et al. Osteosarcoma of the mobile spine. Spine. 2012;37(6):E381–6.

    Article  Google Scholar 

  40. Sciubba DM, Okuno SH, Dekutoski MB, Gokaslan ZL. Ewing and osteogenic sarcoma: evidence for multidisciplinary management. Spine. 2009;34(22 Suppl):S58–68.

    Article  Google Scholar 

  41. Marmor E, Rhines LD, Weinberg JS, Gokaslan ZL. Total en bloc lumbar spondylectomy: Case report. J Neurosurg Spine. 2001;95:264–9.

    Article  CAS  Google Scholar 

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Acknowledgment

It would not have been possible to conceive and finalize this chapter without the collaboration of Carlo Piovani. His work as an archivist and his original drawings are absolutely invaluable.

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Correspondence to Stefano Boriani .

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Karim Ahmed, A., Sciubba, D.M., Boriani, S. (2019). Lumbar En Bloc Resection. In: Sciubba, D. (eds) Spinal Tumor Surgery. Springer, Cham. https://doi.org/10.1007/978-3-319-98422-3_21

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  • DOI: https://doi.org/10.1007/978-3-319-98422-3_21

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