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Myocardial Revascularization in Patients with Left Ventricular Dysfunction

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Heart Failure

Part of the book series: Cardiovascular Medicine ((CVM))

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Abstract

Do patients with ischemic cardiomyopathy benefit from surgical revascularization? This question has been studied extensively over the last 20–30 years and needs to be analyzed from different viewpoints. What is the evidence concerning surgical revascularization of patients with an ejection fraction of 35%? What is the role of percutaneous coronary interventions (PCI) and optimal medical therapy (OMT). What do the guidelines tell us? And are current strategies still timely in view of new developments in the field of end-stage heart failure?

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References

  1. Velazquez E, Lee L, Jones R, Al-Khalidi H, Hill J, Panza J, et al. Coronary-artery bypass surgery in patients with ischemic cardiomyopathy. N Engl J Med. 2016;374(16):1511–20.

    Article  CAS  Google Scholar 

  2. Aldermann EL, Fisher LD, Litwin P, et al. Results of coronary artery surgery in patients with poor left ventricular function (CASS). Circulation. 1983;68:785–95.

    Article  Google Scholar 

  3. The Veterans Administration Coronary Artery Bypass Surgery Cooperative Study Group. Eleven-year survival in the veterans administration randomized trial of coronary bypass surgery for stable angina. N Engl J Med. 1984;311:1333–9.

    Article  Google Scholar 

  4. Varnauskas E, the European Coronary Surgery Study Group. Twelve-year follow-up of survival in the randomized European Coronary Surgery Study. N Engl J Med. 1988;319:332–7.

    Article  CAS  Google Scholar 

  5. Velazquez E, Lee K, Deja M, et al. Coronary-artery bypass surgery in patients with left ventricular dysfunction. N Engl J Med. 2011;364(17):1607–16.

    Article  CAS  Google Scholar 

  6. Elamm C, Fang J. The world post-STITCH: is this a “game changer?” A non-invasive cardiologist’s perspective – revascularisation is the treatment of choice only in patients who fail medical therapy. Prog Cardiovasc Dis. 2013;55:466–9.

    Article  Google Scholar 

  7. Hochman J, Lamas G, Buller C, et al. Coronary intervention for persistent occlusion after myocardial infarction. N Engl J Med. 2006;355:2395–407.

    Article  CAS  Google Scholar 

  8. Boden WE, O’Rourke RA, Teo KK, et al. Optimal medical therapy with or without PCI for stable coronary disease. N Engl J Med. 2007;356:1503–16.

    Article  CAS  Google Scholar 

  9. Hochmann J, Reynolds H, Dzavik V, et al. Long-term effects of percutaneous coronary intervention of the totally occluded infarct-related artery in the subacute phase after myocardial infarction. Circulation. 2011;124(21):2320–8.

    Article  Google Scholar 

  10. Sedlis S, Hartigan P, Teo K, et al. Effect of PCI on long-term survival in patients with stable ischemic heart disease. N Engl J Med. 2015;373(20):1937–46.

    Article  CAS  Google Scholar 

  11. Cleland JG, Calvert M, Freemantle N, et al. The heart failure revascularization trial (HEART). Eur J Heart Fail. 2011;13:227–33.

    Article  Google Scholar 

  12. Cleland JG, Pennell DJ, Ray SG, Coats AJ, Macfarlane PW, Murray GD, et al. Myocardial viability as a determinant of the ejection fraction response to carvedilol in patients with heart failure (CHRISTMAS trial): randomized controlled trial. Lancet. 2003;362:14–21.

    Article  CAS  Google Scholar 

  13. Kunadian V, Pugh A, Zaman AG, Qiu W. Percutaneous coronary intervention among patients with left ventricular systolic dysfunction: a review and meta-analysis of 19 clinical studies. Coron Artery Dis. 2012;23:469–79.

    Article  Google Scholar 

  14. Marui A, Kimura T, Nishiwaki N, et al. Comparison of five-year outcomes of coronary artery bypass grafting versus percutaneous coronary intervention in patients with left ventricular ejection fractions≤50% versus >50% (from the CREDO-Kyoto PCI/CABG Registry Cohort-2). Am J Cardiol. 2014;114:988–96.

    Article  Google Scholar 

  15. Hannan EL, Wu C, Walford G, Culliford AT, Gold JP, Smith CR, Higgins RS, Carlson RE, Jones RH. Drug-eluting stents vs. coronary artery bypass grafting in multivessel coronary disease. N Engl J Med. 2008;358:331–41.

    Article  CAS  Google Scholar 

  16. Hlatky MA, Boothroyd DB, Baker L, Kazi DS, Solomon MD, Chang TI, Shilane D, Go AS. Comparative effectiveness of multivessel coronary bypass surgery and multivessel percutaneous coronary intervention a cohort study. Ann Intern Med. 2013;158:727–35.

    Article  Google Scholar 

  17. Nagendran J, Norris CM, Graham MM, Ross DB, Macarthur RG, Kieser TM, Maitland AM, Southern D, Meyer SR. Coronary revascularization for patients with severe left ventricular dysfunction. Ann Thorac Surg. 2013;96:2038–44.

    Article  Google Scholar 

  18. Hlatky M, Boothroyd D, Bravata D, et al. Coronary artery bypass surgery compared with percutaneous coronary interventions for multivessel disease: a collaborative analysis of individual patient data from ten randomised trials. Lancet. 2009;373:1190–7.

    Article  Google Scholar 

  19. Yang JH, Choi SH, Song YB, Hahn JY, Choi JH, Jeong DS, Sung K, Kim WS, Lee YT, Gwon HC. Long-term outcomes of drug-eluting stent implantation versus coronary artery bypass grafting for patients with coronary artery disease and chronic left ventricular systolic dysfunction. Am J Cardiol. 2013;112:623–9.

    Article  CAS  Google Scholar 

  20. Hillis LD, Smith PK, Anderson JL, et al. 2011 ACCF/AHA guideline for coronary artery bypass graft surgery: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines. Circulation. 2011;124(23):e652–735.

    PubMed  Google Scholar 

  21. Windecker S, Kolh P, Alfonso F, et al. 2014 ESC/EACTS guidelines on myocardial revascularization: the Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J. 2014;35:2541–619.

    Article  Google Scholar 

  22. Yancy CW, Jessup M, Bozkurt B, et al. 2013ACCF/AHAguideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines. Circulation. 2013;128(16):e240–327.

    PubMed  Google Scholar 

  23. Ponikowski P, Voors AA, Anker SD, et al. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart J. 2016;37:2129–200.

    Article  Google Scholar 

  24. Estep J, Starling R, Horstmanshof D. Risk assessment and comparative effectiveness of left ventricular assist device and medical management in ambulatory heart failure patients: results from the ROADMAP study. J Am Coll Cardiol. 2015;66:1747–61.

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of Cardiovascular Surgery, University Hospital Bern, Bern, Switzerland

    D. Reineke & T. Carrel

Authors
  1. D. Reineke
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  2. T. Carrel
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Correspondence to D. Reineke .

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Editors and Affiliations

  1. Division of Cardiology, Department of Medicine, University of Cincinnati, Cincinnati, OH, USA

    David S. Feldman

  2. Clinic im Park, Cardiovascular Center Zürich, Hirslanden Zurich, Switzerland

    Paul Mohacsi

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Reineke, D., Carrel, T. (2019). Myocardial Revascularization in Patients with Left Ventricular Dysfunction. In: Feldman, D., Mohacsi, P. (eds) Heart Failure. Cardiovascular Medicine. Springer, Cham. https://doi.org/10.1007/978-3-319-98184-0_15

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  • DOI: https://doi.org/10.1007/978-3-319-98184-0_15

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-98182-6

  • Online ISBN: 978-3-319-98184-0

  • eBook Packages: MedicineMedicine (R0)

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