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WNT Signaling and Cardiac Fibrosis

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Fibrosis in Disease

Part of the book series: Molecular and Translational Medicine ((MOLEMED))

Abstract

Wnt signaling plays multiple significant roles in cardiac development, injury, repair, and fibrosis. A good understanding of the signaling pathways involved in these processes is a necessary prerequisite in developing therapeutic approaches for different cardiovascular conditions. Our current understanding of these signaling pathways is described in this chapter.

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Authors and Affiliations

  1. Department of Medicine, Division of Cardiology, University of California–Los Angeles, Los Angeles, CA, USA

    Gentian Lluri & Arjun Deb

  2. Department of Molecular, Cell, and Developmental Biology, Broad Stem Cell Research Center, University of California–Los Angeles, Los Angeles, CA, USA

    Arjun Deb

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  1. Gentian Lluri
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Correspondence to Gentian Lluri .

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Editors and Affiliations

  1. Department of Pathology and Laboratory Medicine, Krannert Institute of Cardiology, Indiana University School of Medicine, Indiana Center for Musculoskeletal Health, Indianapolis, IN, USA

    Monte S. Willis

  2. Department of Health Promotion and Development, McGowan Institute for Regenerative Medicine, University of Pittsburgh School of Nursing, Pittsburgh, PA, USA

    Cecelia C. Yates

  3. Department of Pharmacology and Department of Pathology and Lab Medicine, McAllister Heart Institute, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

    Jonathan C. Schisler

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Lluri, G., Deb, A. (2019). WNT Signaling and Cardiac Fibrosis. In: Willis, M., Yates, C., Schisler, J. (eds) Fibrosis in Disease . Molecular and Translational Medicine. Humana Press, Cham. https://doi.org/10.1007/978-3-319-98143-7_11

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  • DOI: https://doi.org/10.1007/978-3-319-98143-7_11

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