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Hypertension and Heart Failure pp 335–348Cite as

Heart Failure with Preserved Ejection Fraction: Current Management and Future Strategies

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Part of the book series: Updates in Hypertension and Cardiovascular Protection ((UHCP))

Abstract

Hypertension (HTN) represents the most important attributable risk factor for heart failure (HF). The measurement of left ventricular (LV) ejection fraction (EF) is the basis for the description of HF in different patients, from those with normal EF (above 50% HF with preserved EF (HFpEF)) to those with reduced EF (below 40%, HF with reduced EF (HFrEF)) [1]. Recent ESC guidelines have identified patients with an LVEF in the range 40–49%, defined as HFmrEF, which in different studies have been considered in the group with HFpEF [2]. HFpEF accounts for about 50% of HF cases, but its prevalence relative to HFrEF continues to rise. HFpEF carries similar risk of morbidity/mortality as HFrEF. Patients with HFpEF are frequently old women with HTN, usually also with diabetes and obesity, characterized by concentric LV hypertrophy (LVH), increased left atrial (LA) size, diastolic dysfunction, pulmonary hypertension, and elevated levels of natriuretic peptides.

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Authors and Affiliations

  1. Clinica Medica, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy

    Enrico Agabiti Rosei & Damiano Rizzoni

Authors
  1. Enrico Agabiti Rosei
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  2. Damiano Rizzoni
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Correspondence to Enrico Agabiti Rosei .

Editor information

Editors and Affiliations

  1. Carol Davila University of Medicine and Pharmacy Bucharest and Cardiology Department, Emergency Clinical Hospital, Bucharest, Romania

    Maria Dorobantu

  2. University of Milano-Bicocca, Milano, Italy

    Giuseppe Mancia  & Guido Grassi  & 

  3. Department of Pharmacology, Toxicology and Clinical Psychopharmacology Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania

    Victor Voicu

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Rosei, E.A., Rizzoni, D. (2019). Heart Failure with Preserved Ejection Fraction: Current Management and Future Strategies. In: Dorobantu, M., Mancia, G., Grassi, G., Voicu, V. (eds) Hypertension and Heart Failure. Updates in Hypertension and Cardiovascular Protection. Springer, Cham. https://doi.org/10.1007/978-3-319-93320-7_21

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  • DOI: https://doi.org/10.1007/978-3-319-93320-7_21

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-93319-1

  • Online ISBN: 978-3-319-93320-7

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