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Comparison of T1 Mapping by Cardiac MRI to Non-cardiac MRI Methods to Evaluate Cardiac Fibrosis

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T1-Mapping in Myocardial Disease

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Abstract

The detection of possible underlying myocardial fibrosis is a common indication for cardiac MRI. In recent years the development of late gadolinium enhancement cardiac MRI (LGE-CMR) and T1 and T2 mapping techniques have revolutionized detection methods, previously predominantly performed by obtaining pathological specimens. Both focal fibrosis (scar) and diffuse fibrosis can be detected noninvasively by other cardiovascular imaging techniques, including nuclear cardiology techniques, echocardiography, and cardiac CT. In this chapter, these techniques are discussed in detail to explore how MRI compares to non-CMR methods of detecting cardiac fibrosis.

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Authors and Affiliations

  1. Non-invasive Cardiovascular Imaging, Cardiovascular Division, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

    Róisín B. Morgan & Raymond Y. Kwong

  2. Department of Radiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

    Michael Jerosch-Herold

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  1. School of Medicine, Stanford University School of Medicine, Stanford, CA, USA

    Phillip C. Yang

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Morgan, R.B., Jerosch-Herold, M., Kwong, R.Y. (2018). Comparison of T1 Mapping by Cardiac MRI to Non-cardiac MRI Methods to Evaluate Cardiac Fibrosis. In: Yang, P. (eds) T1-Mapping in Myocardial Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-91110-6_4

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