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Neonatal Infections pp 207–215Cite as

Zika Virus

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Abstract

Zika virus (ZIKV) arrived in the Americas in 2015 and reached the United States in July, 2016. Although infection is often asymptomatic or produces a self-limited illness, viremia in pregnant women allows transplacental passage of virus, with the potential to result in congenital infection. Several major outbreaks have been reported, with the proportion of affected newborns ranging from 6 to 46%. Congenital Zika syndrome is comprised of a wide range of manifestations, although the main viral tropism is for the central nervous system, resulting in microcephaly and other neurologic abnormalities. Pregnant women with ZIKV exposure who display symptoms of Zika virus disease (ZVD) should be tested with nucleic acid amplification tests and IgM serology to diagnose the cause of their symptoms. For people living in endemic areas, preventing mosquito bites is key to avoid infection, as no specific and effective antiviral treatment is available.

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Author information

Authors and Affiliations

  1. Department of Pediatrics, Universidad del Quindío, Armenia, Colombia

    Juan P. Calle MD

  2. Department of Pediatrics, Universidad del Valle, Cali, Colombia

    Juan P. Calle MD & Eduardo López-Medina MD

  3. Centro de Estudios en Infectología Pediátrica, Cali, Colombia

    Eduardo López-Medina MD

Authors
  1. Juan P. Calle MD
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  2. Eduardo López-Medina MD
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Corresponding author

Correspondence to Eduardo López-Medina MD .

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Editors and Affiliations

  1. University of Texas Health Science Center San Antonio, San Antonio, Texas, USA

    Joseph B. Cantey

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Calle, J.P., López-Medina, E. (2018). Zika Virus. In: Cantey, J. (eds) Neonatal Infections. Springer, Cham. https://doi.org/10.1007/978-3-319-90038-4_24

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  • DOI: https://doi.org/10.1007/978-3-319-90038-4_24

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-90037-7

  • Online ISBN: 978-3-319-90038-4

  • eBook Packages: MedicineMedicine (R0)

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