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Hepatitis B in the Perinatal Period

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Neonatal Infections

Abstract

Chronic hepatitis B virus (HBV) is a significant threat to public health, with an estimated 240 million people living with the disease worldwide (http://www.who.int/mediacentre/factsheets/fs204/en/). HBV and the associated complications, such as cirrhosis and hepatocellular carcinoma, cause >600,000 deaths yearly (GBD 2013 Mortality and Causes of Death Collaborators, Lancet 385:117–71, 2015). Since the development of the HBV vaccine in the 1980s, new cases have decreased, yet the disease remains a global health concern, especially due to high rates of mother-to-child transmission (MTCT) in many countries (http://www.who.int/mediacentre/factsheets/fs204/en/). The focus of this chapter is to explore the current management of hepatitis B in pregnancy, with an emphasis on treatment and prevention of transmission to the neonate.

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Correspondence to Jeanne S. Sheffield MD .

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Pierce-Williams, R.A.M., Sheffield, J.S. (2018). Hepatitis B in the Perinatal Period. In: Cantey, J. (eds) Neonatal Infections. Springer, Cham. https://doi.org/10.1007/978-3-319-90038-4_11

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  • DOI: https://doi.org/10.1007/978-3-319-90038-4_11

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-90037-7

  • Online ISBN: 978-3-319-90038-4

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