Skip to main content
SpringerLink
Log in

Oral Allergy Syndrome: Rethinking Concepts

  • Chapter
  • First Online:
Contact Urticaria Syndrome

Part of the book series: Updates in Clinical Dermatology ((UCD))

  • 387 Accesses

Abstract

This chapter reviews current concepts in our understanding of oral allergy syndrome. As allergen-detecting technology has improved, a much more accurate profiling of individuals with food allergy is now possible to achieve, resulting in more precise diagnosis and leading to the question whether the term “oral allergy syndrome” is still valid.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 139.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Hauser M, Roulias A, Ferreira F, Egger M. Panallergens and their impact on the allergic patient. Allergy Asthma Clin Immunol. 2010;6(1):1.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Webber CM, England RW. Oral allergy syndrome: a clinical, diagnostic, and therapeutic challenge. Ann Allergy Asthma Immunol. 2010;104(2):101–8; quiz 9-10, 17.

    Article  PubMed  Google Scholar 

  3. Sánchez J, Amaya E, Acevedo A, Celis A, Caraballo D, Cardona R. Prevalence of inducible urticaria in patients with chronic spontaneous urticaria: associated risk factors. J Allergy Clin Immunol Pract. 2017;5:464–70.

    Article  PubMed  Google Scholar 

  4. Amlot PL, Kemeny DM, Zachary C, Parkes P, Lessof MH. Oral allergy syndrome (OAS): symptoms of IgE-mediated hypersensitivity to foods. Clin Allergy. 1987;17(1):33–42.

    Article  CAS  PubMed  Google Scholar 

  5. Kondo Y, Urisu A. Oral allergy syndrome. Allergol Int. 2009;58(4):485–91.

    Article  PubMed  Google Scholar 

  6. Konstantinou GN, Grattan CE. Food contact hypersensitivity syndrome: the mucosal contact urticaria paradigm. Clin Exp Dermatol. 2008;33(4):383–9.

    Article  CAS  PubMed  Google Scholar 

  7. Detjen P. Oral allergy syndrome or anaphylaxis? Ann Allergy Asthma Immunol. 1996;77(3):254.

    Article  CAS  PubMed  Google Scholar 

  8. Kelso JM. Oral allergy syndrome? J Allergy Clin Immunol. 1995;96(2):275.

    Article  CAS  PubMed  Google Scholar 

  9. Valenta R, Kraft D. Type 1 allergic reactions to plant-derived food: a consequence of primary sensitization to pollen allergens. J Allergy Clin Immunol. 1996;97(4):893–5.

    Article  CAS  PubMed  Google Scholar 

  10. Ma S, Sicherer SH, Nowak-Wegrzyn A. A survey on the management of pollen-food allergy syndrome in allergy practices. J Allergy Clin Immunol. 2003;112(4):784–8.

    Article  PubMed  Google Scholar 

  11. Ortolani C, Pastorello EA, Farioli L, Ispano M, Pravettoni V, Berti C, et al. IgE-mediated allergy from vegetable allergens. Ann Allergy. 1993;71(5):470–6.

    PubMed  CAS  Google Scholar 

  12. Dreborg S, Foucard T. Allergy to apple, carrot and potato in children with birch pollen allergy. Allergy. 1983;38(3):167–72.

    Article  CAS  PubMed  Google Scholar 

  13. Cuesta-Herranz J, Lázaro M, Figueredo E, Igea JM, Umpiérrez A, De-Las-Heras M. Allergy to plant-derived fresh foods in a birch- and ragweed-free area. Clin Exp Allergy. 2000;30(10):1411–6.

    Article  CAS  PubMed  Google Scholar 

  14. Asero R, Antonicelli L, Arena A, Bommarito L, Caruso B, Crivellaro M, et al. EpidemAAITO: features of food allergy in Italian adults attending allergy clinics: a multi-centre study. Clin Exp Allergy. 2009;39(4):547–55.

    Article  CAS  PubMed  Google Scholar 

  15. Sánchez J, Sánchez A. Epidemiology of food allergy in Latin America. Allergol Immunopathol (Madr). 2015;43(2):185–95.

    Article  PubMed  Google Scholar 

  16. Breiteneder H, Molecular EC. biochemical classification of plant-derived food allergens. J Allergy Clin Immunol. 2000;106(1 Pt 1):27–36.

    Article  CAS  PubMed  Google Scholar 

  17. Valenta R, Duchene M, Ebner C, Valent P, Sillaber C, Deviller P, et al. Profilins constitute a novel family of functional plant pan-allergens. J Exp Med. 1992;175(2):377–85.

    Article  CAS  PubMed  Google Scholar 

  18. Valenta R, Duchêne M, Pettenburger K, Sillaber C, Valent P, Bettelheim P, et al. Identification of profilin as a novel pollen allergen; IgE autoreactivity in sensitized individuals. Science. 1991;253(5019):557–60.

    Article  CAS  PubMed  Google Scholar 

  19. Klinglmayr E, Hauser M, Zimmermann F, Dissertori O, Lackner P, Wopfner N, et al. Identification of B-cell epitopes of Bet v 1 involved in cross-reactivity with food allergens. Allergy. 2009;64(4):647–51.

    Article  CAS  PubMed  Google Scholar 

  20. Hofmann A, Burks AW. Pollen food syndrome: update on the allergens. Curr Allergy Asthma Rep. 2008;8(5):413–7.

    Article  PubMed  Google Scholar 

  21. Ebner C, Hoffmann-Sommergruber K, Breiteneder H. Plant food allergens homologous to pathogenesis-related proteins. Allergy. 2001;56(Suppl 67):43.

    Article  PubMed  Google Scholar 

  22. Ortolani C, Ispano M, Pastorello E, Bigi A, Ansaloni R. The oral allergy syndrome. Ann Allergy. 1988;61(6 t 2):47–52.

    PubMed  CAS  Google Scholar 

  23. Kleine-Tebbe J, Vogel L, Crowell DN, Haustein UF, Vieths S. Severe oral allergy syndrome and anaphylactic reactions caused by a Bet v 1- related PR-10 protein in soybean, SAM22. J Allergy Clin Immunol. 2002;110(5):797–804.

    Article  CAS  PubMed  Google Scholar 

  24. Fernández-Rivas M, Benito C, González-Mancebo E, de Durana DA. Allergies to fruits and vegetables. Pediatr Allergy Immunol. 2008;19(8):675–81.

    Article  PubMed  Google Scholar 

  25. Bohle B, Zwölfer B, Heratizadeh A, Jahn-Schmid B, Antonia YD, Alter M, et al. Cooking birch pollen-related food: divergent consequences for IgE- and T cell-mediated reactivity in vitro and in vivo. J Allergy Clin Immunol. 2006;118(1):242–9.

    Article  CAS  PubMed  Google Scholar 

  26. Tuft L, Blumstein G. Studies in food allergysensitization to fresh fruits: clinical and experimental observations. Journal of Allergy. 1942;13:574–8.

    Article  Google Scholar 

  27. Ortolani C, Ispano M, Pastorello EA, Ansaloni R, Magri GC. Comparison of results of skin prick tests (with fresh foods and commercial food extracts) and RAST in 100 patients with oral allergy syndrome. J Allergy Clin Immunol. 1989;83(3):683–90.

    Article  CAS  PubMed  Google Scholar 

  28. Asero R, Monsalve R, Barber D. Profilin sensitization detected in the office by skin prick test: a study of prevalence and clinical relevance of profilin as a plant food allergen. Clin Exp Allergy. 2008;38(6):1033–7.

    Article  CAS  PubMed  Google Scholar 

  29. Gamboa PM, Sanz ML, Lombardero M, Barber D, Sánchez-Monje R, Goikoetxea MJ, et al. Component-resolved in vitro diagnosis in peach-allergic patients. J Investig Allergol Clin Immunol. 2009;19(1):13–20.

    PubMed  CAS  Google Scholar 

  30. Ballmer-Weber BK, Weber JM, Vieths S, Wüthrich B. Predictive value of the sulfidoleukotriene release assay in oral allergy syndrome to celery, hazelnut, and carrot. J Investig Allergol Clin Immunol. 2008;18(2):93–9.

    PubMed  CAS  Google Scholar 

  31. American College of Allergy At, & Immunology. Food allergy: a practice parameter. Ann Allergy Asthma Immunol. 2006;96(3 Suppl 2):S1–68.

    Google Scholar 

  32. Ballmer-Weber BK, Holzhauser T, Scibilia J, Mittag D, Zisa G, Ortolani C, et al. Clinical characteristics of soybean allergy in Europe: a double-blind, placebo-controlled food challenge study. J Allergy Clin Immunol. 2007;119(6):1489–96.

    Article  PubMed  Google Scholar 

  33. Rodriguez J, Crespo JF, Burks W, Rivas-Plata C, Fernandez-Anaya S, Vives R, et al. Randomized, double-blind, crossover challenge study in 53 subjects reporting adverse reactions to melon (Cucumis melo). J Allergy Clin Immunol. 2000;106(5):968–72.

    Article  CAS  PubMed  Google Scholar 

  34. Anhoej C, Backer V, Nolte H. Diagnostic evaluation of grass- and birch-allergic patients with oral allergy syndrome. Allergy. 2001;56(6):548–52.

    Article  CAS  PubMed  Google Scholar 

  35. Cadot P, Kochuyt AM, van Ree R, Ceuppens JL. Oral allergy syndrome to chicory associated with birch pollen allergy. Int Arch Allergy Immunol. 2003;131(1):19–24.

    Article  CAS  PubMed  Google Scholar 

  36. Asero R. Effects of birch pollen-specific immunotherapy on apple allergy in birch pollen-hypersensitive patients. Clin Exp Allergy. 1998;28(11):1368–73.

    Article  CAS  PubMed  Google Scholar 

  37. Asero R. How long does the effect of birch pollen injection SIT on apple allergy last? Allergy. 2003;58(5):435–8.

    Article  CAS  PubMed  Google Scholar 

  38. Bucher X, Pichler WJ, Dahinden CA, Helbling A. Effect of tree pollen specific, subcutaneous immunotherapy on the oral allergy syndrome to apple and hazelnut. Allergy. 2004;59(12):1272–6.

    Article  CAS  PubMed  Google Scholar 

  39. Kinaciyan T, Jahn-Schmid B, Radakovics A, Zwölfer B, Schreiber C, Francis JN, et al. Successful sublingual immunotherapy with birch pollen has limited effects on concomitant food allergy to apple and the immune response to the Bet v 1 homolog Mal d 1. J Allergy Clin Immunol. 2007;119(4):937–43.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Group of Clinical and Experimental Allergy (GACE), IPS Universitaria, University of Antioquia, Medellín, Colombia

    Jorge Sánchez & Ricardo Cardona

  2. Foundation for the Development of Medical and Biological Sciences (FUNDEMEB), Cartagena, Colombia

    Jorge Sánchez

Authors
  1. Jorge Sánchez
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Ricardo Cardona
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Hospital del Mar - Institut Mar d’Investigacions Mediques, Universitat Autònoma de Barcelona (UAB), Department of Dermatology, Barcelona, Spain

    Ana M. Giménez-Arnau

  2. Department of Dermatology, University of California San Francisco, San Francisco, California, USA

    Howard I. Maibach

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG, part of Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Sánchez, J., Cardona, R. (2018). Oral Allergy Syndrome: Rethinking Concepts. In: Giménez-Arnau, A., Maibach, H. (eds) Contact Urticaria Syndrome. Updates in Clinical Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-319-89764-6_5

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-89764-6_5

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-89763-9

  • Online ISBN: 978-3-319-89764-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation