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Standard Operating Procedures for Common Laboratory Animal Ocular Procedures

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Abstract

In this chapter, we provide a basis for researchers, contract research laboratories, or other investigators to develop harmonized protocols for commonly performed ophthalmic procedures in laboratory animals and to assist in development of institutional standard operating procedure (SOP) documentation. Having similar protocols and SOPs among researchers and institutions will allow better comparison between studies and more efficient use of animals and enhance the quality of ocular research overall. The chapter is organized by procedure and animal species, including techniques such as intracameral, intravitreal, subconjunctival, retrobulbar, and subretinal injections.

Endorsed by the American College of Veterinary Ophthalmologists (ACVO).

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Acknowledgments

The authors thank Justin Prater and David Culp of Powered Research for their assistance.

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Authors and Affiliations

  1. Department of Clinical Sciences, North Carolina State University, Raleigh, NC, USA

    Brian C. Gilger

  2. MPI Research, Mattawan, MI, USA

    Joshua T. Bartoe & Ryan Boyd

  3. Ocular Services On Demand (OSOD), LLC, Madison, WI, USA

    J. Seth Eaton

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  1. Brian C. Gilger
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  2. Joshua T. Bartoe
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  3. J. Seth Eaton
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  4. Ryan Boyd
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Corresponding author

Correspondence to Brian C. Gilger .

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Editors and Affiliations

  1. Department of Clinical Sciences, North Carolina State University, Raleigh, NC, USA

    Brian C. Gilger

  2. Veterinary Vision, San Francisco, CA, USA

    Cynthia S. Cook

  3. Veterinary Ophthalmology Services, Inc., Little Falls, NJ, USA

    Michael H. Brown

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Gilger, B.C., Bartoe, J.T., Eaton, J.S., Boyd, R. (2018). Standard Operating Procedures for Common Laboratory Animal Ocular Procedures. In: Gilger, B., Cook, C., Brown, M. (eds) Standards for Ocular Toxicology and Inflammation. Springer, Cham. https://doi.org/10.1007/978-3-319-78364-2_2

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