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Transfusion Management of the Obstetrical Patient pp 23–37Cite as

Component Therapy in Obstetric Hemorrhage

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Abstract

Postpartum hemorrhage (PPH) remains one of the leading causes of maternal mortality worldwide. Epidemiologic studies have shown a worldwide increase in PPH, extending to developed countries including the United States (US). Although the overall prevalence is low, the rate of PPH in the US has increased from 1.5% in 1999 to 4.1% in 2009 [1]. Numerous national and international societies have invested a great deal of effort in designing Patient Blood Management (PBM) guidelines in an effort to reduce the overall mortality rate associated with PPH. To date, there is no definitive consensus between the various societies’ PBM recommendations. This chapter will highlight a case of life-threatening PPH, detailing blood component therapy in the setting of massive obstetric bleeding. The discussion will include antepartum risk factors for PPH, severity of bleeding assessment, massive transfusion protocols (MTP), lab-directed product replacement, and the use of antifibrinolytic agents. This case and its accompanying information are intended to support the development of an institutional protocol to aggressively manage PPH to reduce the likelihood of hemorrhage-related morbidity and mortality.

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Author information

Authors and Affiliations

  1. Department of Pathology, University of New Mexico, Albuquerque, NM, USA

    Joseph Griggs D.O.

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  1. Joseph Griggs D.O.
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Correspondence to Joseph Griggs D.O. .

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Editors and Affiliations

  1. University of Washington Medical Center, Bloodworks Northwest, Seattle, Washington, USA

    Theresa Nester

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Griggs, J. (2018). Component Therapy in Obstetric Hemorrhage. In: Nester, T. (eds) Transfusion Management of the Obstetrical Patient. Springer, Cham. https://doi.org/10.1007/978-3-319-77140-3_3

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  • DOI: https://doi.org/10.1007/978-3-319-77140-3_3

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-77139-7

  • Online ISBN: 978-3-319-77140-3

  • eBook Packages: MedicineMedicine (R0)

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