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Cancer of Other Origin

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Book cover Serous Effusions

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Abstract

The peritoneal, pleural, and pericardial cavities may be the site of metastasis from practically any malignant tumor, including carcinomas, sarcomas, melanoma, hematological tumors, and pediatric cancers other than the aforementioned entities. The differential diagnosis is critically dependent on the age and gender of the patient, which are in turn likely to impact the choice of immunohistochemistry panels and molecular analyses performed. In adults, carcinomas predominate, and those not originating from the lung, ovary, or breast (discussed in other chapters) are discussed in this chapter, with the main focus on gastrointestinal primaries. Additionally discussed are carcinomas of other origin, including non-ovarian female genital tract cancers and carcinomas of the urothelial tract and the head and neck region. Non-epithelial cancers, including melanoma, sarcomas, and childhood cancers, are additionally discussed. The combination of morphology, immunohistochemistry, and, when mandated, molecular analysis allows for a conclusive diagnosis in the majority of cases.

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Authors and Affiliations

  1. Department of Pathology, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway

    Ben Davidson M.D., Ph.D.

  2. Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway

    Ben Davidson M.D., Ph.D.

  3. UH Cleveland Medical Center, Case Western Reserve University, Cleveland, OH, USA

    Claire Michael M.D.

  4. Department of Pathology, School of Medicine, Koc University, Istanbul, Turkey

    Pınar Fırat

  5. [Previously] Department of Pathology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey

    Pınar Fırat

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  1. Ben Davidson M.D., Ph.D.
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  2. Claire Michael M.D.
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  3. Pınar Fırat
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Correspondence to Ben Davidson M.D., Ph.D. .

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  1. Department of Pathology, The Norwegian Radium Hospital Oslo University Hospital , Oslo, Norway

    Ben Davidson

  2. Department of Pathology, School of Medicine, Koç University, Istanbul, Turkey

    Pinar Firat

  3. UH Cleveland Medical Center, Case Western Reserve University, UH Clevel and Medical Center, Cleveland, Ohio, USA

    Claire W. Michael

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Davidson, B., Michael, C., Fırat, P. (2018). Cancer of Other Origin. In: Davidson, B., Firat, P., Michael, C. (eds) Serous Effusions. Springer, Cham. https://doi.org/10.1007/978-3-319-76478-8_7

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