Abstract
The insular cortex is implied in a great variety of cognitive functions and, for this reason, is probably one of the most studied brain regions in neuroscience. A consistent and increasing number of evidence are defining the role of the insula in meditation, which in recent years has become a hot topic of research in psychology, neuroscience, and medicine. In this chapter we intend to illustrate how the insula is involved in meditation. To this aim, we discuss the well-known and pivotal role of this brain region in attention, salience, and self-awareness, which are key cognitive processes for meditation practice. In virtue of these important functions, the insular cortex proves itself to be a key component of the neural correlates of meditation.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Gogolla N. The insular cortex. Curr Biol. 2017;27:R580–r586.
Craig AD. Significance of the insula for the evolution of human awareness of feelings from the body. Ann N Y Acad Sci. 2011;1225:72–82.
Wiebking C, Duncan NW, Tiret B, Hayes DJ, Marjanska M, Doyon J, Bajbouj M, Northoff G. GABA in the insula—a predictor of the neural response to interoceptive awareness. NeuroImage. 2014;86:10–8.
Gasquoine PG. Contributions of the insula to cognition and emotion. Neuropsychol Rev. 2014;24:77–87.
Garcia-Larrea L, Peyron R. Pain matrices and neuropathic pain matrices: a review. Pain. 2013;154(Suppl 1):S29–43.
Menon V, Uddin LQ. Saliency, switching, attention and control: a network model of insula function. Brain Struct Funct. 2010;214:655–67.
Droutman V, Read SJ, Bechara A. Revisiting the role of the insula in addiction. Trends Cogn Sci. 2015;19:414–20.
Small DM. Taste representation in the human insula. Brain Struct Funct. 2010;214:551–61.
Bamiou DE, Musiek FE, Luxon LM. The insula (island of Reil) and its role in auditory processing. Literature review. Brain Res Brain Res Rev. 2003;42:143–54.
Craig AD. Emotional moments across time: a possible neural basis for time perception in the anterior insula. Philos Trans R Soc Lond Ser B Biol Sci. 2009a;364:1933–42.
Cauda F, D’Agata F, Sacco K, Duca S, Geminiani G, Vercelli A. Functional connectivity of the insula in the resting brain. NeuroImage. 2011;55:8–23.
Cauda F, Costa T, Torta DM, Sacco K, D’Agata F, Duca S, Geminiani G, Fox PT, Vercelli A. Meta-analytic clustering of the insular cortex: characterizing the meta-analytic connectivity of the insula when involved in active tasks. NeuroImage. 2012a;62:343–55.
Manuello J, Vercelli U, Nani A, Costa T, Cauda F. Mindfulness meditation and consciousness: an integrative neuroscientific perspective. Conscious Cogn. 2016;40:67–78.
Kabat-Zinn J. Mindfulness-based interventions in context: past, present, and future. Clin Psychol Sci Pract. 2003;10:144–56.
Awasthi B. Issues and perspectives in meditation research: in search for a definition. Front Psychol. 2012;3:613.
Siegel RD, Germer CK, Olendzki A. Mindfulness: what is it? Where did it come from? In: Didonna F, editor. Clinical handbook of mindfulness. New York: Springer; 2008.
Thera N. Heart of Buddhist meditation. Kandy: Buddhist Publication Society; 1962.
Hölzel BK, Lazar SW, Gard T, Schuman-Olivier Z, Vago DR, Ott U. How does mindfulness meditation work? Proposing mechanisms of action from a conceptual and neural perspective. Perspect Psychol Sci. 2011;6:22.
James W. The principles of psychology. New York: Dover Publications; 1890.
Knudsen EI. Fundamental components of attention. Annu Rev Neurosci. 2007;30:57–78.
Naghavi HR, Nyberg L. Common fronto-parietal activity in attention, memory, and consciousness: shared demands on integration? Conscious Cogn. 2005;14:390–425.
Touroutoglou A, Hollenbeck M, Dickerson BC, Feldman Barrett L. Dissociable large-scale networks anchored in the right anterior insula subserve affective experience and attention. NeuroImage. 2012;60:1947–58.
Reitan RM. Validity of the trail making test as an indicator of organic brain damage. Percept Mot Skills. 1958;8:271–6.
Veldhuizen MG, Small DM. Modality-specific neural effects of selective attention to taste and odor. Chem Senses. 2011;36:747–60.
Taylor PCJ, Rushworth MFS, Nobre AC. Choosing where to attend and the medial frontal cortex: an fMRI study. J Neurophysiol. 2008;100:1397–406.
Bengson JJ, Kelley TA, Mangun GR. The neural correlates of volitional attention: a combined fMRI and ERP study. Hum Brain Mapp. 2015;36:2443–54.
Boehme S, Miltner WH, Straube T. Neural correlates of self-focused attention in social anxiety. Soc Cogn Affect Neurosci. 2015;10:856–62.
Odriozola P, Uddin LQ, Lynch CJ, Kochalka J, Chen T, Menon V. Insula response and connectivity during social and non-social attention in children with autism. Soc Cogn Affect Neurosci. 2016;11:433–44.
Lopez-Larson MP, King JB, Terry J, McGlade EC, Yurgelun-Todd D. Reduced insular volume in attention deficit hyperactivity disorder. Psychiatry Res. 2012;204:32–9.
Morin A. Levels of consciousness and self-awareness: a comparison and integration of various neurocognitive views. Conscious Cogn. 2006;15:358–71.
Ham TE, Bonnelle V, Hellyer P, Jilka S, Robertson IH, Leech R, Sharp DJ. The neural basis of impaired self-awareness after traumatic brain injury. Brain. 2014;137:586–97.
Craig AD. How do you feel—now? The anterior insula and human awareness. Nat Rev Neurosci. 2009b;10:59–70.
Cauda F, Torta DME, Sacco K, Geda E, D’Agata F, Costa T, Duca S, Geminiani G, Amanzio M. Shared “core” areas between the pain and other task-related networks. PLoS One. 2012b;7:e41929.
Craig AD. How do you feel? Interoception: the sense of the physiological condition of the body. Nat Rev Neurosci. 2002;3:655–66.
Farb NAS, Segal ZV, Anderson AK. Mindfulness meditation training alters cortical representations of interoceptive attention. Soc Cogn Affect Neurosci. 2013;8:15–26.
Cauda F, Torta DE, Sacco K, D’Agata F, Geda E, Duca S, Geminiani G, Vercelli A. Functional anatomy of cortical areas characterized by Von Economo neurons. Brain Struct Funct. 2013;218:1–20.
Flynn FG. Anatomy of the insula functional and clinical correlates. Aphasiology. 1999;13:55–78.
Ernst J, Boker H, Hattenschwiler J, Schupbach D, Northoff G, Seifritz E, Grimm S. The association of interoceptive awareness and alexithymia with neurotransmitter concentrations in insula and anterior cingulate. Soc Cogn Affect Neurosci. 2014;9:857–63.
Uddin LQ. Salience processing and insular cortical function and dysfunction. Nat Rev Neurosci. 2015;16:55–61.
Seeley WW, Menon V, Schatzberg AF, Keller J, Glover GH, Kenna H, Reiss AL, Greicius MD. Dissociable intrinsic connectivity networks for salience processing and executive control. J Neurosci. 2007;27:2349–56.
Litt A, Plassmann H, Shiv B, Rangel A. Dissociating valuation and saliency signals during decision-making. Cereb Cortex. 2011;21:95–102.
Palaniyappan L, Liddle PF. Does the salience network play a cardinal role in psychosis? An emerging hypothesis of insular dysfunction. J Psychiatry Neurosci. 2012;37:17–27.
Chen MC, Chang C, Glover GH, Gotlib IH. Increased insula coactivation with salience networks in insomnia. Biol Psychol. 2014;97:1–8.
Hairston IS, Talbot LS, Eidelman P, Gruber J, Harvey AG. Sensory gating in primary insomnia. Eur J Neurosci. 2010;31:2112–21.
Hendrick OM, Luo X, Zhang S, Li CS. Saliency processing and obesity: a preliminary imaging study of the stop signal task. Obesity (Silver Spring). 2012;20:1796–802.
Zhang JT, Yao YW, Li CS, Zang YF, Shen ZJ, Liu L, Wang LJ, Liu B, Fang XY. Altered resting-state functional connectivity of the insula in young adults with Internet gaming disorder. Addict Biol. 2016;21:743–51.
Janes AC, Farmer S, Peechatka AL, Frederick Bde B, Lukas SE. Insula-dorsal anterior cingulate cortex coupling is associated with enhanced brain reactivity to smoking cues. Neuropsychopharmacology. 2015;40:1561–8.
Koob GF, Volkow ND. Neurobiology of addiction: a neurocircuitry analysis. Lancet Psychiatry. 2016;3:760–73.
Sterzer P, Kleinschmidt A. Anterior insula activations in perceptual paradigms: often observed but barely understood. Brain Struct Funct. 2010;214:611–22.
Sridharan D, Levitin DJ, Menon V. A critical role for the right fronto-insular cortex in switching between central-executive and default-mode networks. Proc Natl Acad Sci U S A. 2008;105:12569–74.
Tsai MH, Chou WL. Attentional orienting and executive control are affected by different types of meditation practice. Conscious Cogn. 2016;46:110–26.
Jo HG, Schmidt S, Inacker E, Markowiak M, Hinterberger T. Meditation and attention: a controlled study on long-term meditators in behavioral performance and event-related potentials of attentional control. Int J Psychophysiol. 2016;99:33–9.
Farb N, Mehling WE. Editorial: interoception, contemplative practice, and health. Front Psychol. 2016;7:1898.
Daubenmier J, Sze J, Kerr CE, Kemeny ME, Mehling W. Follow your breath: respiratory interoceptive accuracy in experienced meditators. Psychophysiology. 2013;50:777–89.
Mirams L, Poliakoff E, Brown RJ, Lloyd DM. Brief body-scan meditation practice improves somatosensory perceptual decision making. Conscious Cogn. 2013;22:348–59.
Fox KC, Dixon ML, Nijeboer S, Girn M, Floman JL, Lifshitz M, Ellamil M, Sedlmeier P, Christoff K. Functional neuroanatomy of meditation: a review and meta-analysis of 78 functional neuroimaging investigations. Neurosci Biobehav Rev. 2016;65:208–28.
Lazar SW, Kerr CE, Wasserman RH, Gray JR, Greve DN, Treadway MT, McGarvey M, Quinn BT, Dusek JA, Benson H, et al. Meditation experience is associated with increased cortical thickness. Neuroreport. 2005;16:1893–7.
Holzel BK, Ott U, Gard T, Hempel H, Weygandt M, Morgen K, Vaitl D. Investigation of mindfulness meditation practitioners with voxel-based morphometry. Soc Cogn Affect Neurosci. 2008;3:55–61.
Luders E, Kurth F, Mayer EA, Toga AW, Narr KL, Gaser C. The unique brain anatomy of meditation practitioners: alterations in cortical gyrification. Front Hum Neurosci. 2012;6:34.
Santarnecchi E, D'Arista S, Egiziano E, Gardi C, Petrosino R, Vatti G, Reda M, Rossi A. Interaction between neuroanatomical and psychological changes after mindfulness-based training. PLoS One. 2014;9:e108359.
Fox KC, Nijeboer S, Dixon ML, Floman JL, Ellamil M, Rumak SP, Sedlmeier P, Christoff K. Is meditation associated with altered brain structure? A systematic review and meta-analysis of morphometric neuroimaging in meditation practitioners. Neurosci Biobehav Rev. 2014;43:48–73.
Sato JR, Kozasa EH, Russell TA, Radvany J, Mello LE, Lacerda SS, Amaro E Jr. Brain imaging analysis can identify participants under regular mental training. PLoS One. 2012;7:e39832.
Laneri D, Schuster V, Dietsche B, Jansen A, Ott U, Sommer J. Effects of long-term mindfulness meditation on brain’s white matter microstructure and its aging. Front Aging Neurosci. 2015;7:254.
Tomasino B, Fabbro F. Increases in the right dorsolateral prefrontal cortex and decreases the rostral prefrontal cortex activation after 8 weeks of focused attention based mindfulness meditation. Brain Cogn. 2016;102:46–54.
Tang YY, Tang Y, Tang R, Lewis-Peacock JA. Brief mental training reorganizes large-scale brain networks. Front Syst Neurosci. 2017;11:6.
Tang YY, Ma Y, Fan Y, Feng H, Wang J, Feng S, Lu Q, Hu B, Lin Y, Li J, et al. Central and autonomic nervous system interaction is altered by short-term meditation. Proc Natl Acad Sci U S A. 2009;106:8865–70.
Mascaro JS, Rilling JK, Negi LT, Raison CL. Pre-existing brain function predicts subsequent practice of mindfulness and compassion meditation. NeuroImage. 2013;69:35–42.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer International Publishing AG, part of Springer Nature
About this chapter
Cite this chapter
Manuello, J., Nani, A., Cauda, F. (2018). Attention, Salience, and Self-Awareness: The Role of Insula in Meditation. In: Turgut, M., Yurttaş , C., Tubbs, R. (eds) Island of Reil (Insula) in the Human Brain. Springer, Cham. https://doi.org/10.1007/978-3-319-75468-0_25
Download citation
DOI: https://doi.org/10.1007/978-3-319-75468-0_25
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-75467-3
Online ISBN: 978-3-319-75468-0
eBook Packages: MedicineMedicine (R0)