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Cell Culture Bioprocess Technology: Biologics and Beyond

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Cell Culture Technology

Part of the book series: Learning Materials in Biosciences ((LMB))

Abstract

Scientists have been growing vertebrate cells in culture for over a century. Initially, this cell culture involved placing tissues isolated from animals in a nutrient solution for observation. Eventually, some cells grew out from the tissue explant and began to form cell layers. Over the years, scientists developed a better understanding of the nutritional requirements of cells, established methods to isolate them from tissues and to propagate them, and acquired the ability to use them as tools for conducting research to develop new knowledge on cells and organisms. Ultimately, we learned ways to use them to produce vaccines and medicines.

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Authors and Affiliations

  1. Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN, USA

    Sofie O’Brien, Yonsil Park, Samira Azarin & Wei-Shou Hu

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  1. Department of Biotechnology, University of Natural Resources & Life Sciences, Vienna, Austria

    Cornelia Kasper

  2. Department of Biotechnology, University of Natural Resources & Life Sciences, Vienna, Austria

    Verena Charwat

  3. Institute for Technical Chemistry, Gottfried Wilhelm Leibniz Universität, Hannover, Germany

    Antonina Lavrentieva

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O’Brien, S., Park, Y., Azarin, S., Hu, WS. (2018). Cell Culture Bioprocess Technology: Biologics and Beyond. In: Kasper, C., Charwat, V., Lavrentieva, A. (eds) Cell Culture Technology. Learning Materials in Biosciences. Springer, Cham. https://doi.org/10.1007/978-3-319-74854-2_1

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