Abstract
The vision of the vascular system has undergone many changes during history (Table 2.1). Galen, a native of Pergamon (131–201 bc), was the personal physician of Emperor Marcus Aurelius (Fig. 2.1). He described the circulatory system as a one-way system in which the veins and arteries are only distinguished by the quality of the blood they conveyed [3, 4]. He based his theory on those of predecessors including Erasistratus (304–250 bc), who postulated that veins conveyed blood and arteries only air. In this scheme, veins were connected to the right heart (atrium and right ventricle) and arteries, containing only air, to the left heart (atrium and left ventricle). Galen, in contrast, showed that arteries and veins both contained blood but of different qualities. For Galen, blood had its origin in the liver, passed from the right to the left heart to reach the major blood vessels to be transported to the various tissues, and finally was transformed into flesh. A fraction of the blood was also transported to the lungs, but only to nourish it, and another portion was transported from the right to the left heart through pores located in the septum. The air had the role of cooling blood and conveyed what was called “pneuma.” In the heart, it was transformed into the vital spirit. The arteries conveyed the pneuma and veins and, in addition to blood, several humors (yellow and black bile).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Galen MM (1968) Galen on the usefulness of the parts of the body. Peri chreias morion [romanized form] De usu partium. Cornell University Press, Ithaca, NY
Aird WC (2011) Discovery of the cardiovascular system: from Galen to William Harvey. J Thromb Haemostasis 9(Suppl 1):118–129. https://doi.org/10.1111/j.1538-7836.2011.04312.x
Keele KPC (1979) Leonardo da Vinci. Corpus of anatomical studies in the collection of her majesty the queen at Windsor Castle. Harcourt Brace Jovanovich, New York
Keele K (1972) Leonardo da Vinci’s views on arteriosclerosis. XXIII International Congress of the History of Medicine, London, pp 304–308
Gharib M, Kremers D, Koochesfahani MM, Kemp M (2002) Leonardo’s vision of flow visualization. Exp Fluids 33:219–223
Meyerhof M (1935) Ibn al-Nefis (XII century) and his theory of the lesser circulation. Isis 23:100–120
Akmal M, Zulkifle M, Ansari AH (2010) IBN Nafis – a forgotten genius in the discovery of pulmonary blood circulation. Heart Views 11:26–30
Takrouri MS, Khalaf M (2003) Ibn al-Nafis contributions to science. Middle East J Anaesthesiol 17(2):163–176
Servetus M (1553) CHRISTIANISMI RESTITUTIO: Restoration of Christianity. An English translation of Christianismi Restitutio. Marian Hillar (Traduction), Christopher A. Hoffman (Traduction) Edwin Mellen Press Ltd, 2006
Hofman C, Hillar M (2007/2008) The restauration of Christianity: an English translation of Christianismi restitutio. The Edwin Mellen Press, Lewinston, NY
Columbo MR (1559) De re anatomica libri XV. Nicolò Bevilacqua, Venice
Carlino A (1999) Books of the body: anatomical ritual and renaissance learning. University of Chicago Press, Chicago
Mackall L (1924) A manuscript of the “Christianismi Restitutio” of Servetus, placing the discovery of the pulmonary circulation anterior to 1546. Proc R Soc Med 17(Sect Hist Med):35–38
Chereau A (1879) Histoire du Livre, Michael Servet. Bull Acad de Med de Paris 8:30
Cesalpino A (1571) Peripateticarum quaestiorturn lihri quirtqire. Guinta, Venice
Fye WB (1996) Andrea Cesalpino. Clin Cardiol 19(12):969–970
Giugni F (1959) Further details on the priority in discovery of the circulation of the blood: Andrea Cesalpino or William Harvey? Il Policlinico Sezione pratica 66(Comunicazioni):1294–1297
Aquapendente HF (1603) De Venarum Ostiolis (Trans: Franklin KJ). Published by Charles C Thomas (1933)
Scultetus AH, Villavicencio JL, Rich NM (2001) Facts and fiction surrounding the discovery of the venous valves. J Vasc Surg 33(2):435–441. https://doi.org/10.1067/mva.2001.109772
Wright T (2012) Circulation: William Harvey’s revolutionary idea. Random House, New York
Harvey W (1628) Exercitatio anatomica de motu cordis et sanguini in animalibus. Sumptibus Guiliemi Fitzeri, Frankfurt
D’Arcy Power FSA (1897) William Harvey. T. FISHER UNWIN, London
Franklin KJ (1961) King Charles I and William Harvey. Proc Roy Soc Med 54:85–91
Schwann T (1847) Microscopical researches into the accordance in the structure and growth of animals and plants. Sydenham Society, London
Malpighi M (1663) De pulmonibus observationibus anatomicæ. De pulmonum substantia & Motu diatribæ. Mathhiæ Godicchii, sumptibus Petri Hauboldi, Copenhagen
Bailly M (1771) Nouvelles Litteraires: Vie de Malpighi. In: Observation sur la Physique, sur l’Histoire Naturelle et sur les Arts, Tome Premier, vol Hotel de Thou, Rue des Piotevins. Paris, pp 73–79
Van Leeuwenhoek A (1674) Microscopical observations concerning blood, milk, bones, the brain, spittle, and cuticula. Philos Trans 9:121–128
Ruysch F (1691) Observationum anatomico-chirurgicarum centuria. Amsterdam 2. Aufl. 1721: 3. Aufl. 1737
Earle JW (1835) On the nature of inflammation. Lond Med Gaz 16:6–12
Döllinger I (1821) Vom Kreislauf des Blutes. München
Dollinger I (1805) Naturlehre des Menschlichen Organismus. Jos. Anton Goebhardt, Bamberg und Würzburg
Society R (1831) Dr Marshall Hall on the capillary circulation. Lond Med Gaz 8
Müller J (1833) Handbuch der Physiologie des Menschen für Vorlesungen. J. Hölscher Coblenz
His W (1865) Die Häute und Höhlen des Körpers. Schwighauser, Basel
Koelliker A (1879) Entwicklungsgeschichte des Menschen und der höheren Tiere. Bremen University Press (July 2, 2014), Paperback Edition. Publisher Language: German. ISBN-10:3955626423, Leipzig
Müller J, Baly W, Bell J (1843) Elements of physiology. Lea and Blanchard, Philadelphia, PA
Müller J (1844) Handbuch der Physiologie des Menschen für Vorlesungen, vol Vierte verbesserte Auflage. Verlag von J. Hölscher, Coblenz
Dowler B (1849) Researches, critical and experimental, upon the capillary circulation. New Orleans Med Surg J V:447–477
Rouget CBM (1847) Note sur le développement de la tunique contractile des vaisseaux. Comptes rendus hebdomadaires des séances de l’ Académie des sciences 79:559–562
Zimmermann KW (1923) Der feinere Bau der Blutkapillaren. Z Anat Entwicklungsgesch 68:29–109
Mayer S (1902) Die Muskularisierung der capillaren Blutgefässe. Anat Anz 21:442–455
Hwa C, Aird WC (2007) The history of the capillary wall: doctors, discoveries, and debates. Am J Phys Heart Circ Phys 293(5):H2667–H2679. https://doi.org/10.1152/ajpheart.00704.2007
Slack CB (1843) On abnormal nutrition and on the mode in which its different products are developed. In: Improvements and discoveries in the medical sciences: medical pathology and therapeutics and pratical medicine. Am J Med Sci:441–443
Addison W (1843) Experimental research with the microscope, in physiology and pathology. First Series: On the Blood, Inflammation &c. John Churchill, London
Rather LJ (1972) Addison and the white corpuscles: an aspect of nineteenth-century biology. University of California Press, Berkley, CA
Cohnheim J (1867) Ueber Entzündung und Eiterung. Archiv für pathologische Anatomie und Physiologie und für klinische Medicin 40(1–2):1–79
Heidland A, Klassen A, Sebekova K, Bahner U (2009) Beginning of modern concept of inflammation: the work of Friedrich Daniel von Recklinghausen and Julius Friedrich Cohnheim. J Nephrol 22(Suppl 14):71–79
Clark ER, Clark EI (1935) Observations on changes in blood vascular endothelium in the living animal. Am J Anat 57:388–438
Otteley D (1839) John Hunter F.R.S. Haswell, Barrington, and Haswell, Philadelphia, PA
Schechter DC, Bergan JJ (1986) Popliteal aneurysm: a celebration of the bicentennial of John Hunter’s operation. Ann Vasc Surg 1(1):118–126. https://doi.org/10.1016/S0890-5096(06)60712-7
Hunter J (1794) A treatise on the blood, inflammation, and gunshot wounds. Gryphon Editions Ltd., Birmingham
Bennett JH (1849) On cancerous and cancroid growths. Prov Med Surg J 13(12):324–326
Thiersch C (1869) Der Epithelialkrebs, namentlich der Haut mit Atlas: Eine Anatomisch-Klinische Untersuchung. Verlag von Wilhelm Engelmann, Leipzig
Tremain Hertig A (1935) Angiogenesis in the early human chorion and in the primary placenta of the macaque monkey, Contributions to embryology, vol 25. Carnegie Institution of Washington Publication, Washington, DC
Clark ER, Hitschler WJ, Kirby-Smith HT, Rex RO, Smith JH (1931) General observations on the ingrowth of new blood vessels into standardized chambers in the rabbit’s ear, and the subsequent changes in the newly grown vessels over a period of months. Anat Rec 50:129–167
Broca P (1849) Quelques propositions sur les tumeurs dites cancéreuses. Thèse pour le doctorat en Médecine, Paris
Broca P (1866) Traité des Tumeurs, vol 1. P Asselin, Paris
Goldmann E (1907) The growth of malignant disease in man and the lower animals, with special reference to the vascular system. Lancet 2:1236–1240
Goldmann E (1908) The growth of malignant disease in man and the lower animals, with special reference to the vascular system. Proc Roy Soc Med 1(Surg Sect):1–13
Greene HS (1941) Heterologous transplantation of mammalian tumors: I. The transfer of rabbit tumors to alien species. J Exp Med 73(4):461–474
Greene HS (1941) Heterologous transplantation of mammalian tumors: II. The transfer of human tumors to alien species. J Exp Med 73(4):475–486
Greene HS (1938) Heterologous transplantation of human and other mammalian tumors. Science 88(2285):357–358. https://doi.org/10.1126/science.88.2285.357
Clark ER, Clark EI (1939) Microscopic observations on the growth of blood capillaries in the living mammals. Am J Anat 64:251–301
Algire GH, Chalkley HW (1945) Vascular reactions of normal and malignant tissue in vivo. J Natl Cancer Inst 6:73–85
Algire GH, Legallais FY (1948) Growth and vascularization of transplanted mouse melanomas. Ann N Y Acad Sci 4:159–170
Merwin RM, Algire GH (1956) The role of graft and host vessels in the vascularization of grafts of normal and neoplastic tissue. J Natl Cancer Inst 17(1):23–33
Ide AG, Baker NH, Warren SL (1939) Vascularization of the Brown-Pearce rabbit epithelioma transplant as seen in the transparent ear chambers. AJR 32:891–899
Greenblatt M, Shubi P (1968) Tumor angiogenesis: transfilter diffusion studies in the hamster by the transparent chamber technique. J Natl Cancer Inst 41(1):111–124
Ehrmann RL, Knoth M (1968) Choriocarcinoma. Transfilter stimulation of vasoproliferation in the hamster cheek pouch. Studied by light and electron microscopy. J Natl Cancer Inst 41(6):1329–1341
Huang X, Molema G, King S, Watkins L, Edgington TS, Thorpe PE (1997) Tumor infarction in mice by antibody-directed targeting of tissue factor to tumor vasculature. Science 275(5299):547–550
Aselli G (1627) De lactibus sive lacteis venis quarto vasorum mesaraicorum genere, novo invento Gaspariis Asellii Cremonensis anatomici Ticinensis dissertatio, qua sententiae anatomicae multae, vel perperam receptae conuelluntur, vel parum perceptae illustrantur. apud Jo. Baptistam Bidellium, Mediolani
Pecquet J (1651) Experimenta nova anatomica, quibus incognitum chyli receptaculum, et ab eo per thoracem in ramosusque subclavis vasa lactea deteguntur. Apud Sebastianum Cramoisy et Gabrielem Cramoisy, Paris
Bartholin T (1653) Vasa Lymphaticia, Nuper Hafniae in Animantibus Inventa, et Hepatis Exsequiae Holst, Copenhague
Rudbeck O (1653) Nova Exercitatio Anatomica Exhibens Ductus Hepaticos Aquosus et Vasa Glandularum Serosa. Lauringer, Vasteras
Palmer JF (1837) The works of John Hunter with notes, vol IV. Longman, Rees, Orme, Brown, Green and Longman, London
Hewson W (1774) The lymphatic systems in the human subject, and in other animals. J Johnson, London
Ludwig C (1852–1856) Lehrbuch der Physiologie des Menschen, vol 2. Akademische Verlagshandlung CF Winter, Heidelberg
Fye WB (1986) Carl Ludwig and the Leipzig Physiological Institute: ‘a factory of new knowledge’. Circulation 74(5):920–928
von Recklinghausen F (1860) Eine methode, mikroskopische hohle und solide gebilde voneinander zu unterscheiden. Virchows Arch 19
Sabin FR (1902) On the origin of the lymphatic system from the veins and the development of the lymph hearts and thoracic duct in the pig. Am J Anat 1:367–389
Sabin FR (1916) The method of growth of the lymphatic system. Science 44(1127):145–158. https://doi.org/10.1126/science.44.1127.145
Clark ER (1909) Observations on living growing lymphatics in the tail of the frog larva. Anat Rec 6(261)
Clark ER, Clark EL (1933) Further observations on living lymphatic vessels in the transparent chamber in the rabbit’s ear-their relation to the tissue spaces. Am J Anat 52:273
Clark ER, Clark EL (1937) Observations on living mammalian lymphatic capillaries-their relation to the blood vessels. Am J Anat 60:253
Clark ER, Clark EL (1938) Observations of isolated lymphatic capillaries in the living mammal. Am J Anat 62(1):59–92
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer International Publishing AG, part of Springer Nature
About this chapter
Cite this chapter
Bikfalvi, A. (2017). History of the Vascular System. In: A Brief History of Blood and Lymphatic Vessels. Springer, Cham. https://doi.org/10.1007/978-3-319-74376-9_2
Download citation
DOI: https://doi.org/10.1007/978-3-319-74376-9_2
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-74375-2
Online ISBN: 978-3-319-74376-9
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)