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Childhood Growth Hormone Deficiency and Hypopituitarism

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Pediatric Endocrinology

Abstract

Hypopituitarism is the deficiency in varying degrees of one or multiple pituitary hormones. In this chapter, deficiency of growth hormone (GH) will be discussed, while other hormonal deficiencies are presented elsewhere in this book. To understand GH deficiency (GHD), the mechanisms of GH production and its secretion are first presented. There are multiple etiologies of GHD, and an ever-increasing number of genetic causes have been uncovered. However, the ability to make the diagnosis of GHD still remains difficult, and interpretation of laboratory studies remains controversial.

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Authors and Affiliations

  1. Division of Endocrinology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA

    Carmen L. Soto-Rivera MD & Laurie E. Cohen MD

  2. Division of Pediatric Endocrinology and Diabetes, Icahn School of Medicine at Mount Sinai, New York, NY, USA

    Christopher J. Romero MD

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  1. Carmen L. Soto-Rivera MD
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  2. Christopher J. Romero MD
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  3. Laurie E. Cohen MD
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Correspondence to Laurie E. Cohen MD .

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Editors and Affiliations

  1. Department of Pediatrics, Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA

    Sally Radovick

  2. Pediatric Endocrinology, Massachusetts General Hospital for Children, Boston, Massachusetts, USA

    Madhusmita Misra

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Soto-Rivera, C.L., Romero, C.J., Cohen, L.E. (2018). Childhood Growth Hormone Deficiency and Hypopituitarism. In: Radovick, S., Misra, M. (eds) Pediatric Endocrinology. Springer, Cham. https://doi.org/10.1007/978-3-319-73782-9_1

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