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Disorders of Thyroid Hormone Transporters and Receptors

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The Thyroid and Its Diseases

Abstract

Thyroid hormone transporters and receptors are crucial factors that determine the biological effects of thyroid hormone. This chapter deals with disorders that result from abnormal function of the thyroid hormone transporter MCT8 and of either the thyroid hormone receptor isoforms (resistance to thyroid hormone, RTH). The clinical and biochemical phenotypes, imaging modalities, underlying mechanisms, and treatment options are discussed for MCT8 deficiency, RTH-alpha, and RTH-beta.

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Author information

Authors and Affiliations

  1. Department of Internal Medicine, Erasmus Medical Centre, Rotterdam, The Netherlands

    W. Edward Visser

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  1. W. Edward Visser
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Correspondence to W. Edward Visser .

Editor information

Editors and Affiliations

  1. Department of Nuclear Medicine, Philipps University Marburg, Marburg, Germany

    Markus Luster

  2. Unit of Endocrinology Diabetes and Metabolism, Evgenidion Hospital, National and Kapodistrian University of Athens, Athens, Greece

    Leonidas H. Duntas

  3. Georgetown University School of Medicine, Washington, DC, USA

    Leonard Wartofsky

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Visser, W.E. (2019). Disorders of Thyroid Hormone Transporters and Receptors. In: Luster, M., Duntas, L., Wartofsky, L. (eds) The Thyroid and Its Diseases. Springer, Cham. https://doi.org/10.1007/978-3-319-72102-6_4

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  • DOI: https://doi.org/10.1007/978-3-319-72102-6_4

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-72100-2

  • Online ISBN: 978-3-319-72102-6

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