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Anatomic Abnormalities and Recurrent Implantation Failure

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Abstract

Intrauterine abnormalities such as myomas, polyps, adhesions, and congenital septa have been shown to adversely affect embryo implantation and pregnancy outcomes. Treating these conditions improves pregnancy rates and outcomes. Hydrosalpinges reduce IVF pregnancy rates by ~50% by impeding embryo implantation. Treating them prior to IVF by salpingectomy, salpingostomy, or tubal ligation restores the success rates back to normal. This chapter reviews the pathophysiology of these abnormalities, therapeutic options, and treatment results.

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Goldberg, J.M., Gingold, J., Llarena, N. (2018). Anatomic Abnormalities and Recurrent Implantation Failure. In: Franasiak, J., Scott Jr., R. (eds) Recurrent Implantation Failure. Springer, Cham. https://doi.org/10.1007/978-3-319-71967-2_10

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