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Stent Thrombosis

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Abstract

Coronary stents constitute the default strategy during percutaneous coronary intervention (PCI) as they provide improved safety and efficacy compared with balloon angioplasty alone. Stents reduce restenosis rates compared to balloon angioplasty predominantly as a result of a larger acute gain that translates into a greater minimal lumen diameter at follow-up. Although neointimal proliferation is increased after bare metal stent (BMS) implantation, eventually the net lumen gain at follow-up is larger than that obtained with balloon angioplasty. Drug-eluting stents (DES) significantly reduced neointimal proliferation and the need for reinterventions as compared with BMS. In addition, the safety of PCI improved after the introduction of coronary stents that drastically reduced the incidence of abrupt vessel closure. However, stent thrombosis still remains an important and feared complication. This entity has a wide chronological spectrum encompassing anywhere from intra-procedural to many years after implantation.

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Author information

Authors and Affiliations

  1. Department of Cardiology, Hospital Universitario de La Princesa, Universidad Autónoma de Madrid, Madrid, Spain

    Javier Cuesta, Marcos García-Guimaraes, Fernando Rivero, Teresa Bastante & Fernando Alfonso

Authors
  1. Javier Cuesta
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  2. Marcos García-Guimaraes
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  3. Fernando Rivero
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  4. Teresa Bastante
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  5. Fernando Alfonso
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Editor information

Editors and Affiliations

  1. Brighton and Sussex Medical School and the Sussex Cardiac Centre, Brighton and Sussex University Hospitals NHS Trust, Brighton, UK

    Aung Myat

  2. Royal Papworth Hospital NHS Foundation Trust, Papworth Everard, Cambridge, UK

    Sarah Clarke

  3. Wessex Cardiothoracic Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK

    Nick Curzen

  4. Department of Cardiology, Bern University Hospital, Bern, Switzerland

    Stephan Windecker

  5. Inova Center for Thrombosis Research and Drug Development, Inova Heart and Vascular Institute, Falls Church, VA, USA

    Paul A. Gurbel

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Cuesta, J., García-Guimaraes, M., Rivero, F., Bastante, T., Alfonso, F. (2018). Stent Thrombosis. In: Myat, A., Clarke, S., Curzen, N., Windecker, S., Gurbel, P.A. (eds) The Interventional Cardiology Training Manual. Springer, Cham. https://doi.org/10.1007/978-3-319-71635-0_22

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  • DOI: https://doi.org/10.1007/978-3-319-71635-0_22

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-71633-6

  • Online ISBN: 978-3-319-71635-0

  • eBook Packages: MedicineMedicine (R0)

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