Abstract
The main causes of liver disease in an acutely unwell older child are viral infection, drug injury or metabolic liver disease (Table 5.1). A thorough history may help distinguish from drug or toxin induced liver injury.
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Further Reading
Alonso E, Squires R. Acute liver failure. In: Kelly DA, editor. Diseases of the liver and biliary system in children, vol. 2017. 4th ed. Hoboken: Wiley. p. 271–90.
Devarbhavi H, Singh R, Adarsh CK, Sheth K, Kiran R, Patil M. Factors that predict mortality in children with Wilson disease associated acute liver failure and comparison of Wilson disease specific prognostic indices. J Gastroenterol Hepatol. 2014;29:380–6.
Lu BR, Zhang S, Narkewicz MR, et al. Evaluation of the liver injury unit scoring system to predict survival in a multinational study of pediatric acute liver failure. J Pediatr. 2013;162:1010-6.e1–4.
Squires RH Jr, Shneider BL, Bucuvalas J, et al. Acute liver failure in children: the first 348 patients in the pediatric acute liver failure study group. J Pediatr. 2006;148:652–8.
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Kelly, D. (2018). The Acutely Ill Child. In: Kelly, D., Sharif, K., Hartley, J. (eds) Atlas of Pediatric Hepatology. Springer, Cham. https://doi.org/10.1007/978-3-319-69529-7_5
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DOI: https://doi.org/10.1007/978-3-319-69529-7_5
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