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Tumors in Pigmented Skin

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Abstract

Skin cancer is worldwide the most common malignancy; non-melanoma skin cancer and malignant melanoma together represent 40% of all neoplasms in white Caucasians [1]. The worldwide incidence for basal cell carcinoma varies widely with highest rates in Australia >1000/100,000/person-year and lowest in parts of Africa <1/100,000/person-year. In the UK the average incidence rates were 76/100,000/person-year and 22/100,000 person-year for basal cell and squamous cell carcinoma, respectively [2]. In individuals with pigmented ethnic skin, the incidence of skin cancer is clearly lower as compared with white-skinned individuals, possibly as a result of the photoprotective effects of melanin [3], but skin cancer is often associated with greater mortality and morbidity in pigmented skin. This may be associated either with late diagnosis of the neoplasms in an advanced stage or with different tumor characteristics in populations with pigmented ethnic skin. It is important to further assess any differences of skin cancer between Caucasian and non-Caucasian populations and evaluate the etiology and risk factors in skin of color for developing cancer.

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Assaf, C., Amani, A.U., Yildiz, E., Hwang, S.T. (2018). Tumors in Pigmented Skin. In: Orfanos, C., Zouboulis, C., Assaf, C. (eds) Pigmented Ethnic Skin and Imported Dermatoses. Springer, Cham. https://doi.org/10.1007/978-3-319-69422-1_36

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