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The Role of 18FDG-PET/CT in Malignant Lymphomas: Clinical Implications

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Imaging in Clinical Oncology

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Abstract

PET/CT has a key role in final response assessment after treatment in most types of malignant lymphomas, as well as in baseline staging and interim (mid-treatment) evaluation. Its application is widely established in Hodgkin lymphoma (HL) and aggressive B-cell lymphomas, including diffuse large B-cell lymphoma (DLBCL), primary mediastinal large B-cell lymphoma (PMLBCL), and other related subtypes. Although recent recommendations suggest the use of PET/CT for baseline staging and response assessment in follicular lymphomas, mantle cell lymphoma (MCL), Burkitt lymphoma, and “nodal” T-cell lymphomas [anaplastic large cell (ALCL), peripheral T-cell (PTCL), and angioimmunoblastic T-cell lymphoma (AITL)], the accumulated clinical experience with these subtypes is considerably less. The role of PET/CT is much more controversial in non-follicular low-grade lymphomas and primary extranodal lymphomas other than DLBCL.

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Authors and Affiliations

  1. Department of Haematology, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece

    Theodoros P. Vassilakopoulos

  2. Departments of Nuclear Medicine and PET/CT, Hygeia Hospital, Athens, Greece

    Vassilios K. Prassopoulos

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  1. Theodoros P. Vassilakopoulos
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Editors and Affiliations

  1. School of Medicine, National and Kapodistrian, University of Athens, Athens, Greece

    Athanasios D. Gouliamos

  2. Imaging Department, Hygeia and Mitera Hospitals, Athens, Greece

    John A. Andreou

  3. Medical Oncologist, Head, Medical Oncology Department, Hygeia Hospital, Athens, Greece

    Paris A. Kosmidis

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Vassilakopoulos, T.P., Prassopoulos, V.K. (2018). The Role of 18FDG-PET/CT in Malignant Lymphomas: Clinical Implications. In: Gouliamos, A., Andreou, J., Kosmidis, P. (eds) Imaging in Clinical Oncology. Springer, Cham. https://doi.org/10.1007/978-3-319-68873-2_94

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