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Advances in Treatments for Aortic Valve and Root Diseases pp 137–143Cite as

4D Flow Imaging in Aortic Disease

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Abstract

The flow hemodynamics in the aorta plays a critical role in the formation and development of aortic disease. 4D flow imaging using phase-contrast magnetic resonance (4D PC-MRI) has been developed and performed in both research and clinical care to study the blood flow in the heart and the great vessels. Compared to 2D flow imaging, 4D PC-MRI allows retrospective visualization and quantification of the time-varying 3D blood flow pattern in the 3D volume of the aorta, and provides more comprehensive visual and quantitative tools to study the complex relationship between flow hemodynamics and aortic pathophysiology in the development of aortic disease. In this chapter, we will describe the image acquisition technique, the image pre-processing method, the data visualization technique, and the quantitative hemodynamic markers of the 4D flow PC-MRI in the aorta. This chapter will also give an overview of the potential clinical applications of the flow visualization and the flow quantifications derived from 4D flow imaging for aortic disease.

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Authors and Affiliations

  1. Department of Cardiovascular Imaging, Piedmont Heart Institute, Atlanta, GA, USA

    Zhen Qian Ph.D. & Mani Vannan M.B.B.S.

  2. Department of Cardiology, Chinese PLA General Hospital, Beijing, China

    Xiao Zhou M.D. Ph.D.

Authors
  1. Zhen Qian Ph.D.
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  2. Xiao Zhou M.D. Ph.D.
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  3. Mani Vannan M.B.B.S.
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Corresponding author

Correspondence to Zhen Qian Ph.D. .

Editor information

Editors and Affiliations

  1. Department of Cardiothoracic and Vascular Surgery, GVM Care and Research, MEH, University of Palermo, Palermo, Italy

    Khalil Fattouch

  2. Department of Cardiology, University of Liège, Liège, Belgium

    Patrizio Lancellotti

  3. Marcus Heart Valve Center, Piedmont Heart Institute, Atlanta, GA, USA

    Mani A. Vannan

  4. Cardiovascular Surgery Department, GVM Care & Research, Anthea Hospital, Bari, Italy

    Giuseppe Speziale

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Qian, Z., Zhou, X., Vannan, M. (2018). 4D Flow Imaging in Aortic Disease. In: Fattouch, K., Lancellotti, P., Vannan, M., Speziale, G. (eds) Advances in Treatments for Aortic Valve and Root Diseases. Springer, Cham. https://doi.org/10.1007/978-3-319-66483-5_9

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  • DOI: https://doi.org/10.1007/978-3-319-66483-5_9

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-66482-8

  • Online ISBN: 978-3-319-66483-5

  • eBook Packages: MedicineMedicine (R0)

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