Abstract
During the past decade, Onyx® HD-500 (Medtronic Neurovascular, USA), a high-viscosity liquid embolic agent, has been used extensively to treat intracranial aneurysms. Preliminary experience using this relatively novel agent was rewarding in terms of high-occlusion rates and low-recanalization rates of large and wide-necked aneurysms [1, 2]. Use of Onyx HD-500 has since decreased dramatically with the increasing popularity of flow diverters as first-line treatment for complex intracranial aneurysms. Nevertheless, it remains a useful endovascular tool for select patients who are not good candidates for flow diversion because of recurrent stent-embolized aneurysms or nickel allergy.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Mawad ME, Cekirge S, Ciceri E, Saatci I. Endovascular treatment of giant and large intracranial aneurysms by using a combination of stent placement and liquid polymer injection. J Neurosurg. 2002;96:474–82.
Tevah J, Senf R, Cruz J, Fava M. Endovascular treatment of complex cerebral aneurysms with Onyx HD-500(®) in 38 patients. J Neuroradiol. 2011;38:283–90.
Molyneux AJ, Cekirge S, Saatci I, Gál G. Cerebral Aneurysm Multicenter European Onyx (CAMEO) trial: results of a prospective observational study in 20 European centers. AJNR Am J Neuroradiol. 2004;25:39–51.
Simon SD, Eskioglu E, Reig A, Mericle RA. Endovascular treatment of side wall aneurysms using a liquid embolic agent: a US single-center prospective trial. Neurosurgery. 2010;67:855–60.
Cekirge HS, Saatci I, Ozturk MH, Cil B, Arat A, Mawad M, et al. Late angiographic and clinical follow-up results of 100 consecutive aneurysms treated with Onyx reconstruction: largest single-center experience. Neuroradiology. 2006;48:113–26.
ev3 Inc. Onyx® HD-500. http://www.ev3.net/neuro/us/liquid-embolics/onyx-hd500-liquid-embolic-system.htm. Accessed 31 Oct 2011.
Weber W, Siekmann R, Kis B, Kuehne D. Treatment and follow-up of 22 unruptured wide-necked intracranial aneurysms of the internal carotid artery with Onyx HD 500. AJNR Am J Neuroradiol. 2005;26:1909–15.
Piske RL, Kanashiro LH, Paschoal E, Agner C, Lima SS, Aguiar PH. Evaluation of Onyx HD-500 embolic system in the treatment of 84 wide-neck intracranial aneurysms. Neurosurgery. 2009;64:E865–75.
Rahme R, Ringer AJ, Abruzzo TA, Grande AW, Jimenez L. Predicting parent vessel patency and treatment durability: a proposed grading scheme for the immediate angiographic results following Onyx HD-500 embolization of intracranial aneurysms. J Neurointerv Surg. 2014;6(10):754–60.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer International Publishing AG, part of Springer Nature
About this chapter
Cite this chapter
Ringer, A.J., Rahme, R. (2018). Aneurysm Treatment with Liquid Embolics. In: Gandhi, C., Prestigiacomo, C. (eds) Cerebrovascular and Endovascular Neurosurgery. Springer, Cham. https://doi.org/10.1007/978-3-319-65206-1_27
Download citation
DOI: https://doi.org/10.1007/978-3-319-65206-1_27
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-65204-7
Online ISBN: 978-3-319-65206-1
eBook Packages: MedicineMedicine (R0)