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Mixed Vitiligo

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Abstract

By definition, mixed vitiligo (MV) is the association of a characteristic segmental involvement associated usually in a second step with the onset of bilateral vitiligo patches. The association of segmental vitiligo (SV) to vitiligo/nonsegmental vitiligo (vitiligo/NSV) suggests a continuum between the two subsets which were formerly opposed. A common mode of revelation is a segment resistant to phototherapy in a patient diagnosed previously as vitiligo/NSV. Halo nevi and leukotrichia at first consultation in segmental vitiligo are risk factors for the progression of SV to MV. In addition, this progression of SV to MV carries a stronger link if the segment is initially situated on the trunk. Combined somatic mosaicism and immune dysregulation may explain the continuum SV-vitiligo/NSV in the case of MV.

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Author information

Authors and Affiliations

  1. Service de Dermatologie, Hôpital Saint-André, CHU de Bordeaux, Bordeaux, France

    Alain Taïeb

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  1. Alain Taïeb
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Correspondence to Alain Taïeb .

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Editors and Affiliations

  1. Cutaneous Physiopathology & CIRM, San Gallicano Dermatological Institute, Rome, Italy

    Mauro Picardo

  2. Hôpital Saint André, Service de Dermatologie Adulte et Pédiatrique, INSERM U 1035, Université de Bordeaux, Bordeaux, France

    Alain Taïeb

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Taïeb, A. (2019). Mixed Vitiligo. In: Picardo, M., Taïeb, A. (eds) Vitiligo. Springer, Cham. https://doi.org/10.1007/978-3-319-62960-5_7

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  • DOI: https://doi.org/10.1007/978-3-319-62960-5_7

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-62958-2

  • Online ISBN: 978-3-319-62960-5

  • eBook Packages: MedicineMedicine (R0)

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