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Endocrine Disruption in the Siberian Sturgeon Acipenser baerii Fed with a Soy-Containing Diet

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The Siberian Sturgeon (Acipenser baerii, Brandt, 1869) Volume 2 - Farming

Abstract

Under the South-West climate conditions, the fish reproductive maturity was reached within 6–8 years allowing the development of a local caviar production. While studying the reproductive physiology of this fish, an estrogenic endocrine disruption was discovered. We managed showing that it was mainly due to soy-based diet containing estrogenic isoflavones. Because the rainbow trout reared in the same conditions did not exhibit such a disruption, we studied the effects of soy isoflavones at different steps of the estrogen endocrine pathways in both species. We managed to show that sturgeon was 50 times more sensitive to estrogenic soy isoflavones than trout. We also showed that this difference of sensitivity was not linked to differences at the estradiol synthesis step nor at the estradiol blood transport step. It was neither due to differences at the estradiol receptor levels nor at the liver cell level. The 50 times difference of sensitivity between the two species was linked to a difference in isoflavone bioavailability due to different xenobiotics detoxifying efficiency of the liver. Genistein, the main soy estrogenic compound, was shown to exhibit deleterious effect on trout reproduction. Until now the effect of this compound and of others from soy is still unknown on sturgeon reproduction due to the late reproductive maturity of this species. Studies are required to check for better reproductive efficiency of this species in the French fish-farm conditions.

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Notes

  1. 1.

    Dpm: disintegrations per minutes applied to the transformation of radioactive compounds.

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Authors and Affiliations

  1. University of Bordeaux, 351, Cours de la Libération, 33 405, Talence Cedex, France

    Catherine Bennetau-Pelissero

  2. Bordeaux Sciences Agro, Cours du Général de Gaulle, 33 175, Gradignan, France

    Catherine Bennetau-Pelissero

  3. 26, rue Gustave Flaubert, 33 600, Pessac, France

    Françoise Le Menn

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  1. Catherine Bennetau-Pelissero
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  2. Françoise Le Menn
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Correspondence to Catherine Bennetau-Pelissero .

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Editors and Affiliations

  1. Audenge, France

    Patrick Williot

  2. La Teste de Buch, France

    Guy Nonnotte

  3. State Center for Sturgeon Gene Pool Conservation “Kubanbioresursi”, Kuban State University, Krasnodar, Russia

    Mikhail Chebanov

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Bennetau-Pelissero, C., Le Menn, F. (2018). Endocrine Disruption in the Siberian Sturgeon Acipenser baerii Fed with a Soy-Containing Diet. In: Williot, P., Nonnotte, G., Chebanov, M. (eds) The Siberian Sturgeon (Acipenser baerii, Brandt, 1869) Volume 2 - Farming. Springer, Cham. https://doi.org/10.1007/978-3-319-61676-6_7

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