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Biopsy and Oral Squamous Cell Carcinoma Histopathology

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Oral Cancer Detection

Abstract

Oral cancer is a fairly common disease, which is unfortunately often diagnosed when it has reached an advanced stage. Early diagnosis is crucial for better prognosis and survival. In addition to better survival figures, early diagnosis also provides sufferers with a better quality of life. Biopsy is widely accepted as the “gold standard” diagnostic method for lesions raising suspicion of malignancy. There are several types of biopsy including incisional biopsy, excisional biopsy, fine needle aspiration, punch biopsy, and brush biopsy, each with specific indications, special methodology, advantages, and disadvantages. The use of biopsy and analyzing the results under the microscope is the gold standard for confirming a diagnosis of oral squamous cell carcinoma diagnosis. Biopsy is indicated in mucosal lesions (especially ulcers), and it is of critical importance to reveal oral dysplasia, to confirm the clinical suspicion for an early invasive cancer, or to establish the grade of differentiation of oral squamous cell carcinoma for accurate therapeutic procedure and in the determination of prognosis.

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Author information

Authors and Affiliations

  1. Department of Oral Medicine/Pathology, School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece

    Dimitrios A. Andreadis DDS, PhD & Achilleia-Maria Pavlou DDS, MSc

  2. Department of Oral Medicine and Radiology, MNR Dental College and Hospital, Sangareddy, Telangana, India

    Prashanth Panta MDS

Authors
  1. Dimitrios A. Andreadis DDS, PhD
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  2. Achilleia-Maria Pavlou DDS, MSc
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  3. Prashanth Panta MDS
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Corresponding author

Correspondence to Dimitrios A. Andreadis DDS, PhD .

Editor information

Editors and Affiliations

  1. Depatment of Oral Medicine and Radiology, MNR Dental College Oral Medicine and Radiology, Hyderabad, India

    Prashanth Panta

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Andreadis, D.A., Pavlou, AM., Panta, P. (2019). Biopsy and Oral Squamous Cell Carcinoma Histopathology. In: Panta, P. (eds) Oral Cancer Detection. Springer, Cham. https://doi.org/10.1007/978-3-319-61255-3_6

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  • DOI: https://doi.org/10.1007/978-3-319-61255-3_6

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-61254-6

  • Online ISBN: 978-3-319-61255-3

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